Sulfonamides

ABSTRACT

Sulfonamides of the general formula I ##STR1## where R 1  is hydrogen of C 1  -C 4  -alkyl, 
     R 2  is hydrogen or substituted or unsubstituted C 1  -C 6  -alkyl; C 3  -C 4  -alkenyl; C 3  -C 4  -alkynyl or substituted or unsubstituted saturated or singly unsaturated 5- to 7- membered heteroaryl; 
     R 3  and R 4  are halogen; substituted or unsubstituted C 1  -C 4  -alkoxy C 1  -C 4  -alkylthio, C 2  -C 6  -alkenyl, C 2  -C 6  -alkenyloxy, C 2  -C 6  -alkenylthio, C 2  -C 6  -alkynyl, C 2  -C 6  -alkynyloxy, C 2  -C 6  -alkynylthio, C 3  -C 6  -cycloalkyl, C 3  -C 6  -cycloalkylthio, C 5  -C 6  -cycloalkenyl, C 3  -C 6  -cycloalkoxy, C 5  -C 6  -cycloalkenyloxy, C 5  -C 6  -cycloalkenylthio, phenyl, phenoxy, phenylthio, benzyl, benzyloxy or benzylthio; 
     the group given for R 2 , or NR 7  R 8 , where R 7  and R 8  are hydrogen, C 1  -C 6  -alkyl, C 3  -C 6  -alkenyl, C 3  -C 6  -alkynyl, C 3  -C 6  -cycloalkyl, C 5  -C 6  -cycloalkenyl, substituted or unsubstituted phenyl and/or benzyl bedeuten, or is 
     substituted or unsubstituted C 4  -C 6  -alkylene which may be interrupted or oxygen, sulfur or nitrogen; 
     X is nitrogen or ═CR 5  14 , 
     where R 5  is one of the radicals R 3 , 
     n is 0 or 1 and 
     A is substituted or unsubstituted mono- or dinuclear aryl containing one or two nitrogen, oxygen and/or sulfur atoms, 
     and their agriculturally useful salts, and herbicidal and growth-regulating agents containing them.

The present invention relates to sulfonamides of the general formula I ##STR2## where R¹ is hydrogen or C₁ -C₄ -alkyl,

R² is hydrogen,

a C₁ -C₆ -alkyl which can be substituted by one to five halogens and/or one of the following: C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy, C₁ -C₄ -alkylthio, C₁ -C₄ -haloalkylthio, phenyl, phenoxy or phenylthio;

a C₃ -C₄ -alkenyl, a C₃ -C₄ -alkynyl;

a saturated or singly unsaturated 5- to 7-membered heterocycle which contains one or two nitrogen, oxygen and/or sulfur atoms and which can have one to three of the following substituents: halogen, C₁ -C₄ -alkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkyl, C₁ -C₄ -haloalkoxy, C₁ -C₄ -alkylthio, C₁ -C₄ -haloalkylthio and/or phenyl, phenoxy and/or phenylthio;

R³ and R⁴ are halogen;

C₁ -C₄ -alkoxy, C₁ -C₄ -alkylthio, C₂ -C₆ -alkenyl, C₂ -C₆ -alkenyloxy, C₂ -C₆ -alkenylthio, C₂ -C₆ -alkynyl, C₂ -C₆ -alkynyloxy and/or C₂ -C₆ -alkynylthio, it being possible for these radicals to be substituted by one to five halogens and/or by one of the following groups: C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy, C₁ -C₄ -alkylthio, C₁ -C₄ -haloalkylthio, phenyl, phenoxy or phenylthio;

C₃ -C₆ -cycloalkyl, C₃ -C₆ -cycloalkylthio, C₅ -C₆ -cycloalkenyl, C₃ -C₆ -cycloalkoxy, C₅ -C₆ -cycloalkenyloxy, C₅ -C₆ -cycloalkenylthio, phenyl, phenoxy, phenylthio, benzyl, benzyloxy or benzylthio, it being possible for these cyclic groups to be substituted by one to five halogens and/or one to three of the following:

C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy, C₁ -C₄ -alkylthio, C₁ -C₄ -haloalkylthio, phenyl, phenoxy, phenylthio, benzyl, benzyloxy and/or benzylthio; the groups mentioned under R² or

NR⁷ R⁸ where

R⁷ and R⁸ are hydrogen, C₁ -C₆ -alkyl, C₃ -C₆ -alkenyl, C₃ -C₆ -alkynyl, C₃ -C₆ -cycloalkyl, C₅ -C₆ -cycloalkenyl, phenyl and/or benzyl, it being possible for the aromatic rings in turn to be substituted once to five times by halogen and/or once to three times by C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy and/or C₁ -C₄ -haloalkoxy or together are a C₄ -C₆ -alkylene bridge which can be interrupted by an oxygen, sulfur or a nitrogen atom, it being possible for these bridges in turn to carry one to three C₁ -C₄ -alkyl groups;

X is nitrogen or ═CR⁵ -- where R⁵ is one of the radicals R³,

n is 0 or 1 and

A is a mono- or dinuclear aromatic radical which can contain one or two nitrogen, oxygen and/or sulfur atoms and can carry one to five halogens and/or one to three of the following: cyano, nitro, thiocyanato, the radicals R³, COR⁶ where R⁶ is hydroxyl, amino or one of the radicals R³ and SO_(m) R⁶ where m is 1 or 2,

and the salts thereof which can be used in agriculture.

The present invention also relates to a process for the preparation of these compounds and to the use thereof for controlling undesired plant growth and for influencing plant growth.

EP-A-150,974 describes sulfonamides which have a herbicidal action. However, they do not meet all requirements, e.g. with regard to selectivity and specific action.

Hence the object of the present invention was to find and synthesize substances with satisfactory properties.

In accordance with this object, we have found the sulfonamides I defined in the first paragraph.

The present invention also relates to processes for the preparation of these compounds I, herbicides and agents for influencing plant growth, which contain the novel compounds as active ingredients, and a process for influencing and controlling plant growth with these compounds.

The compounds I according to the invention can be obtained in a variety of ways similar to known conversion methods. As Examples, seven processes (A to G) are explained below.

Process A

The compounds I are obtained in a conventional manner (J. Med. Chem. 9 (1966), 373) by reacting an appropriate sulfonamide II in an inert organic solvent in the presence of a base with a heteroaryl halide III as shown below. ##STR3## Hal in formula III is a halogen such as fluorine, chlorine, bromine and iodine, and particularly suitable compounds III are those in which Hal is chlorine or bromine.

Solvents expediently used for these reactions are halohydrocarbons, e.g. tetrachloroethane, methylene chloride, chloroform, dichloroethane, chlorobenzene and 1,2-dichlorobenzene; ethers, e.g. diethyl ether, methyl tert-butyl ether, dimethoxyethane, diethylene glycol dimethyl ether, tetrahydrofuran and dioxane; dipolar aprotic solvents, e.g. acetonitrile, dimethylformamide, dimethylacetamide, dimethyl sulfoxide, N-methylpyrrolidone, 1,3-dimethyltetrahydro-2(1H)-pyrimidinone and 1,3-dimethylimidazolidin-2-one; aromatics, e.g. benzene, toluene, xylene, pyridine and quinoline; ketones, e.g. acetone, methyl ethyl ketone; alcohols, e.g. methanol, ethanol, isopropanol and t-butanol, or mixtures thereof.

The reaction can be carried out at from 25° C. to the reflux temperature of the particular solvent or mixture thereof.

Bases used as catalysts in this reaction are aromatic nitrogen bases such as pyridine, 4-dimethylaminopyridine and quinoline; tertiary aliphatic amines such as triethylamine, ethyldiisopropylamine and N-methylmorpholine; bi- and tricyclic amines such as diazabicycloundecene (DBU) or diazabicyclooctane (DABCO), and hydroxides, hydrides, alkoxides, carbonates and bicarbonates of alkali metals and alkaline earth metals, in particular NaOH, KOH, NaH, KH, CaH₂, LiH, NaOMe, NaOEt, KOtBu, Na₂ CO₃, K₂ CO₃, NaHCO₃, KHCO₃. It is also sometimes useful to employ combinations of these bases.

The molar ratios of the starting compounds used in the reaction are generally from 1:1 to 1:3 for the ratio of sulfonamide II to heteroaryl halide III and from 1:1 to 1:3 for the ratio of sulfonamide II to catalytic base.

The concentration of the precursors in the solvent is generally from 0.1 to 5 mol/l, preferably from 0.2 to 2 mol/l.

The reaction is particularly preferably carried out in aprotic dipolar solvents such as acetonitrile, dimethylformamide, dimethyl sulfoxide, N-methylpyrrolidone, 1,3-dimethyltetrahydro-2(1H)-pyrimidinone, 1,3-dimethylimidazolidin-2-one or ethers such as 1,2-dimethoxyethane, diethylene glycol dimethyl ether, tetrahydrofuran or dioxane, at from 80° C. to 150° C., using sodium hydride, sodium methylate, sodium ethylate or potassium tert-butylate as bases. It has proven particularly advantageous initially to convert the sulfonamide II, by reaction with the base, into its salt and then to react the latter with the heteroaryl halide III. It is possible to isolate the sulfonamide salt, but it is unnecessary and, in fact, it is extremely expedient merely to generate the sulfonamide salt in situ and react it further with the heteroaryl halide III in the same reaction medium.

Many of the sulfonamides of the general formula II which are required are commercially available. Novel sulfonamides of the formula II can be prepared by conventional methods (Pawlenko, Houben-Weyl, Methoden der organischen Chemie, volume E 11, Organic Sulfur Compounds, G. Thieme Verlag, Stuttgart (1985), pp. 1098 et seq.).

The heteroaryl halides of the general formula III which are required can also be obtained by conventional methods (Shaw; Comprehensive Heterocyclic Chemistry (The Structure, Reaction, Synthesis and Uses of Heterocyclic Compounds), Vol. 5, 1st ed. (1984), Chapter 4.09, pp. 499 et seq.; Montgomery, J. A. Secrist III in Comprehensive Heterocyclic Chemistry, Vol. 5, 1st ed. (1984), Chapter 4.10, pp. 615 et seq., and pp. 635 et seq.; Lister, The Chemistry of Heterocyclic Compounds, Fused Pyrimidines, Part II, Purines (1971) and Robins, Heterocyclic Compounds, Vol. 8, pp. 162 et seq. (1967)).

Process B

The compounds I with R² ≠H are also obtained by reacting an appropriate sulfonyl halide IV in a conventional manner in an inert organic solvent in the presence of a base with a heteroarylamine V where R² is not hydrogen, as shown below: ##STR4## Hal in formula IV is a halogen such as fluorine, chlorine and bromine, especially chlorine.

It is possible in principle to use for this reaction the solvents and bases, and combinations thereof, mentioned for process A, at from 25° C. to the reflux temperature of the particular solvent or mixture thereof. Addition of a base is unnecessary with basic solvents such as pyridine.

The molar ratio of the starting compounds is generally from 1:1 to 1:3 for the ratio of heteroarylamine V to catalytic base. However, it is also possible for the sulfonyl halides IV and the reaction-accelerating bases to be employed in less than the stoichiometric amount in each case.

The concentration of the precursors in the solvent is generally from 0.1 to 5 mol/l, preferably from 0.2 to 2 mol/l.

The sulfonyl halides of the general formula IV which are required are commercially available or can be prepared by conventional methods (Clarke et al., Org. Synth. Coll. Vol. I, 2nd ed., 1941, pp. 85 et seq.; Hoffmann, Org, Synth., Vol. 60, pp. 121 et seq.). The heteroarylamines of the general formula V required for the reaction can be prepared by conventional methods. These methods are described in the literature cited in connection with the heteroaryl halides of the general formula II in process A.

Process C

Compounds I where R¹ is hydrogen are obtained, for example, by reacting a sulfonyl isocyanide derivative of the formula VI in a conventional manner (Synthesis 11 (1982), 984; Chem. Ber. 99 (1966), 2885) with a diaminoheteroaryl derivative of the formula VIIa or VIIb, in the presence or absence of a base, as shown below. ##STR5## Z in formula VI is a halogen such as chlorine or bromine, or C₁ -C₄ -alkylthio or benzylthio, with chlorine and methylthio being preferred.

These reactions are carried out in one of the chlorohydrocarbons, ethers, aromatic or aprotic dipolar solvents or mixtures thereof mentioned in process A, at from 25° C. to the boiling point of the solvent or mixture.

The reactions in this process are particularly preferably carried out in halohydrocarbons such as chlorobenzene, 1,2-dichlorobenzene; aromatics such as toluene, xylene; ethers such as 1,2-dimethoxyethane, diethylene glycol dimethyl ether, dioxane or aprotic dipolar solvents such as acetonitrile, dimethylformamide, dimethylacetamide, dimethyl sulfoxide, N-methylpyrrolidone, 1,3-dimethyltetrahydro-2(1H)-pyrimidinone and 1,3-dimethylimidazolidin-2-one at from 80° C. to 150° C. The molar ratio of the starting compounds used in the reaction is generally from 1:1 to 1:5 for the ratio of derivatives of the general formula VI to diaminoheteroaryl compounds of the general formula VIIa or VIIb, with the concentration of the precursors in the solvent being from 0.1 to 5 mol/l, preferably from 0.2 to 2 mol/l.

It is advantageous, particularly in reactions of sulfonyl isocyanide dihalides of the general formula VI where Z is halogen, to carry out the reaction in the presence of at least 2 mol-equivalents of a base to bind the hydrogen halide produced in the reaction.

Preferred bases are aromatic nitrogen bases such as pyridine, 4-dimethylaminopyridine or quinoline, tertiary aliphatic amines such as triethylamine, ethyldiisopropylamine or N-methylmorpholine, bi- and tricyclic amines such as diazabicycloundecene (DBU) or diazabicyclooctane (DABCO) or, particularly advantageously, diaminoheteroaryl derivatives of the general formula VIIa or VIIb.

The sulfonyl isocyanide derivatives of the general formula VI which are required can be prepared by conventional methods (Kuhler, Houben-Weyl, Methoden der Organischen Chemie, Volume E4, Carbonic acid derivatives, G. Thieme Verlag, Stuttgart (1983), pp. 540 et seq., 584 et seq.). The diaminoheteroaryl derivatives of the general formula VIIa or VIIb required for the reaction can be prepared by conventional methods (J. Brown, Comprehensive Heterocyclic Chemistry, Vol. 3, 1st ed. (1984), Chapter 2.13, pp. 57 et seq.; Jones, Comprehensive Chemistry, vol. 2, 1st ed. (1984), Chapter 2.08, pp. 395 et seq.).

Process D

In a modification of the process described under C, the compounds I where R¹ is hydrogen are also obtained by reacting a suitable N-sulfonylhalothioformimidic alkyl or benzyl ester VIa with a diaminoheteroaryl derivative VIIa or VIIb and subsequently cyclizing the isothiourea VIIIa or VIIIb to give the desired sulfonamide I (J. Org. Chem. 42 (1977), 3065). ##STR6## Hal in formula VIa is chlorine or bromine, and R is C₁ -C₄ -alkyl or benzyl, with chlorine and methyl being preferred.

It is possible in principle to employ for the reactions shown in the diagram to give the isothiourea derivatives of the general formula VIIIa or VIIIb the solvents mentioned in process A, in combination with the bases listed in process C, preferably at from 0° C. to 50° C.

The subsequent cyclization of the isothioureas VIIIa or VIIIb to give the sulfonamides I is carried out in all cases using the diluents and bases mentioned in process C, similar to Rapoport et al. (Journal of Organic Chemistry, 42 (1977), 2065) in the presence of at least one mol-equivalent of a silver salt, with silver nitrate being preferred. The precursors of the general formula VIa required for the reaction are obtained by conventional methods (e.g. Kuhle, Houbey-Weyl, Methoden der organische Chemie, Volume E4, Carbonic acid derivatives, G. Thieme Verlag, Stuttgart (1983), p. 551 and literature cited therein).

Process E

Compounds I where neither R¹ nor R² is hydrogen are also obtained, for example, by reacting an appropriate sulfonamide IX in a conventional manner in an organic solvent in the presence of a base with an alkylating reagent X where Nu is a nucleophilic leaving group and R¹ is not hydrogen, as shown below. ##STR7## It is expedient to use for this reaction inert solvents and mixtures thereof, as detailed in process A.

These reactions can be carried out at from 25° C. to the reflux temperature of the solvent or mixture thereof.

The bases used are those detailed in process A. It is possible to use the base as solvent, in which case no additional solvent is necessary.

The molar ratio of the starting compounds is generally from 1:1 to 1:3 (compound IX to electrophile X) or 1:1 to 1:5 (compound IX to base). The concentration of the precursors in the solvent is generally from 0.1 to 5 mol/l, preferably from 0.2 to 2 mol/l.

The alkylating reagents X used are, in particular, C₁ -C₄ -alkyl chlorides, bromides, iodides, benzenesulfonates, p-bromobenzenesulfonates, p-methylbenzenesulfonates, di-C₁ -C₄ -alkyl sulfates and tri-C₁ -C₄ -alkyloxonium tetrafluoroborates. The compounds X are generally commercially available or can be prepared by conventional methods.

The sulfonamides of the general formula IX with R² ≠H can be obtained by processes A-D described above.

Process F

Compounds of the general formula I where R³ and/or R⁴ is alkoxy, alkylthio, phenoxy or a substituted amino, and X is nitrogen, are obtained particularly advantageously by reacting a sulfonamide derivative XIa or XIb where Hal is halogen such as fluorine, chlorine, bromine, especially chlorine, and R³ in the formula XIb is not halogen or phenoxy, with an appropriate alcohol, thiol, phenol or amine XIIa or XIIb in a conventional manner in an organic solvent in the presence of a base as shown below. ##STR8## It is possible in principle to use for these reactions the solvents and bases, and the combinations thereof, mentioned in process A. The ratio of the reagent of the formula XIIa or XIIb to the sulfonamide XIa or XIb is preferably from 1:1 to 5:1, especially 3:1 to 5:1, and the reaction is carried out in a solvent such as an alcohol, e.g. methanol, ethanol, propanol, iso-propanol, n-butanol, iso-butanol, tert-butanol, ether, e.g. diethyl ether, methyl tert-butyl ether, 1,2-dimethoxyethane, tetrahydrofuran, dioxane, or aprotic dipolar solvent, e.g. acetonitrile, dimethylformamide or dimethyl sulfoxide, at from room temperature to 130° C.

Process G

In a modification of the process described under F, compounds of the general formula I where R³ and R⁴ are identical alkoxy, alkylthio, phenoxy, alkylamino, dialkylamino or alkyleneamino groups, and X is nitrogen, are obtained by reacting an appropriate sulfonamide derivative XIc with the derivative XIIa or XII in an organic solvent in the presence of a base as shown below. ##STR9## Hal in the formula XIc is fluorine, chlorine or bromine, especially chlorine.

The reaction is carried out under conditions similar to those described in process F.

The nucleophiles of the general formula XIIa or XIIb are generally commercially available or can be prepared from known precursors in a straightforward and conventional manner. The sulfonamides XIa, XIb and XIc can be obtained by processes A-E described above.

Suitable and preferred substituents having regard to the intended use of the compounds I are the following:

R¹ is hydrogen or C₁ -C₄ -alkyl such as methyl, ethyl, n-propyl, iso-propyl, n-butyl, sec-butyl, iso-butyl and tert-butyl, especially methyl, ethyl, propyl and iso-propyl

R² is hydrogen, allyl; propargyl; alkyl as mentioned for R¹, and pentyl, 1-methylbutyl, 2-methylbutyl, 3-methylbutyl, 1,1-dimethylpropyl, 1,2-dimethylpropyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl, 1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 4-methylpentyl, 1,1-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2,2-dimethylbutyl, 2,3-dimethylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl, 2-ethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl, 1-ethyl-1-methylpropyl and 1-ethyl-2-methylpropyl, especially methyl, ethyl, propyl and iso-propyl, which can be substituted by one to five halogens, especially fluorine and/or chlorine, or one of the following: alkoxy such as methoxy, ethoxy, n-propoxy, 2-methylethoxy, n-butoxy, 1-methylpropoxy, 2-methylpropoxy and 1,1-dimethylethoxy, especially methoxy, ethoxy, 1-methylethoxy and 1,1-dimethylethoxy;

haloalkoxy such as difluoromethoxy, trifluoromethoxy, chlorodifluoromethoxy, dichlorofluoromethoxy, 1-fluoroethoxy, 2-fluoroethoxy, 2,2-difluoroethoxy, 1,1,2,2-tetrafluoroethoxy, 2,2,2-trifluoroethoxy, 2-chloro-1,1,2-trifluoroethoxy and pentafluoroethoxy, especially trifluoromethoxy and pentafluoroethoxy;

alkylthio such as methylthio, ethylthio, propylthio, 1-methylethylthio, butylthio, 1-methylpropylthio, 2-methylpropylthio and 1,1-dimethylethylthio, especially methylthio and ethylthio;

haloalkylthio such as difluoromethylthio, trifluoromethylthio, chlorodifluoromethylthio, 1-fluoroethylthio, 2-fluoroethylthio, 2,2-difluoroethylthio, 2,2,2-trifluoroethylthio, 2-chloro-2,2-difluoroethylthio, 2,2-dichloro-2-fluoroethylthio, 2,2,2-trichloroethylthio and pentafluoroethylthio, especially difluoromethylthio and pentafluoroethylthio; phenyl or phenylthio;

a 5- to 7-membered saturated or singly unsaturated heterocycle such as tetrahydrofuryl, tetrahydrothienyl, dioxolanyl, dithiolanyl, oxathiolanyl, pyrazolidinyl, dihydropyrazolyl, imidazolidinyl, dihydroimidazolyl, isoxazolidinyl, dihydroisoxazolyl, oxazolidinyl, dihydrooxazolyl, isothioazolidinyl, dihydroisothiazolyl, thiazolidinyl, dihydrothiazolyl, tetrahydropyran-3-yl, dihydropyran-3-yl, tetrahydropyran-4-yl, tetrahydropyran-2-yl, dihydropyran-4-yl, tetrahydrothiopyran-3-yl, dihydrothiopyran-3-yl, tetrahydrothiopyran-4-yl, dihydrothiopyran-4-yl and dioxepan-5-yl, piperidinyl, tetrahydro-1,3-oxazinyl, tetrahydro-1,4-oxazinyl, tetrahydro-1,3-thiazinyl, tetrahydro-1,4-thiazinyl, perhydro-1,3-oxazepinyl, perhydro-1,4-oxazepinyl, perhydro-1,3-thiazepinyl, perhydro-1,4-thiazepinyl and perhydroazepinyl, it being possible for this ring to carry one to three of the following substituents:

halogen, such as fluorine, chlorine, bromine and iodine, especially fluorine and chlorine; alkyl as mentioned for R¹, especially methyl, ethyl, propyl and iso-propyl;

alkoxy as mentioned above, especially methoxy, ethoxy, 1-methylethoxy and 1,1-dimethylethoxy; haloalkyl such as fluoromethyl, difluoromethyl, trifluoromethyl, chlorodifluoromethyl, dichlorofluoromethyl, trichloromethyl, 1-fluoroethyl, 2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl, 2-chloro-2,2-difluoroethyl, 2,2-dichloro-2-fluoroethyl, 2,2,2-trichloroethyl and pentafluoroethyl, especially trifluoromethyl;

haloalkoxy as mentioned above, especially trifluoromethoxy, trifluoroethoxy and chloroethoxy;

alkylthio as mentioned above, especially methylthio and ethylthio;

haloalkylthio as mentioned above, especially difluoromethylthio and pentafluoroethylthio and/or phenyl, phenoxy or phenylthio;

R³ and R⁴ are, independently of one another, halogen as mentioned for R², especially fluorine and chlorine; alkoxy as mentioned for R², especially methoxy, ethoxy, 1-methylethoxy and 1,1-dimethylethoxy; alkylthio as mentioned for R², especially methylthio and ethylthio;

alkenyl such as ethenyl, 1-propenyl, 2-propenyl, 1-methylethenyl, 1-butenyl, 2-butenyl, 3-butenyl, 1-methyl-1-propenyl, 1-methyl-2-propenyl, 2-methyl-1-propenyl, 2-methyl-2-propenyl, 1-pentenyl, 2-pentenyl, 3-pentenyl, 4-pentenyl, 1-methyl-1-butenyl, 2-methyl-1-butenyl, 3-methyl-2-butenyl, 1-methyl-2-butenyl, 2-methyl-2-butenyl, 3-methyl-2-butenyl, 1-methyl-3-butenyl, 2-methyl-3-butenyl, 3-methyl-3-butenyl, 1,1-dimethyl-2-propenyl, 1,1-dimethyl-1-propenyl, 1,2-dimethyl-2-propenyl, 1-ethyl-1-propenyl, 1-ethyl-2-propenyl, 1-hexenyl, 2-hexenyl, 3-hexenyl, 4-hexenyl, 5-hexenyl, 1-methyl-1-pentenyl, 2-methyl-1-pentenyl, 3-methyl-1-pentenyl, 4-methyl-1-pentenyl, 1-methyl-2-pentenyl, 2-methyl-2-pentenyl, 3-methyl-2-pentenyl, 4-methyl-2-pentenyl, 1-methyl-3-pentenyl, 2-methyl-3-pentenyl, 3-methyl-3-pentenyl, 4-methyl-3-pentenyl, 1-methyl-4-pentenyl, 2-methyl-4-pentenyl, 3-methyl-4-pentenyl, 4-methyl-4-pentenyl, 1,1-dimethyl-2-butenyl, 1,1-dimethyl-3-butenyl, 1,2-dimethyl-1-butenyl, 1,2-dimethyl-2-butenyl, 1,2-dimethyl-3-butenyl, 1,3-dimethyl-1-butenyl, 1,3-dimethyl-2-butenyl, 1,3-dimethyl-3-butenyl, 2,2-dimethyl-3-butenyl, 2,3-dimethyl-1-butenyl, 2,3-dimethyl-2-butenyl, 2,3-dimethyl-3-butenyl, 3,3-dimethyl-1-butenyl, 1-ethyl-1-butenyl, 1-ethyl-2-butenyl, 1-ethyl-3-butenyl, 2-ethyl-1 -butenyl, 2-ethyl-2-butenyl, 2-ethyl-3-butenyl, 1,1,2-trimethyl-2-propenyl, 1-ethyl-1-methyl-2-propenyl, 1-ethyl-2-methyl-1-propenyl and 1-ethyl-2-methyl-2-propenyl, especially allyl and, in general and in particular, corresponding alkenyloxy and/or alkenylthio;

alkynyl such as ethynyl, 1-propynyl, propargyl, 1-butynyl, 2-butynyl, 3-butynyl, 1-methyl-2-propynyl, 1-pentynyl, 2-pentynyl, 3-pentynyl, 4-pentynyl, 1-methyl-3-butynyl, 2-methyl-3-butynyl, 1-methyl-2-butynyl, 3-methyl-1-butynyl, 1,1-dimethyl-2-propynyl, 1-ethyl-2-propynyl, 1-hexynyl, 2-hexynyl, 3-hexynyl, 4-hexynyl, 5-hexynyl, 1-methyl-2-pentynyl, 1-methyl-3-pentynyl, 1-methyl-4-pentynyl, 2-methyl-3-pentynyl, 2-methyl-4-pentynyl, 3-methyl-1-pentynyl, 3-methyl-4-pentynyl, 4-methyl-1-pentynyl, 4-methyl-2-pentynyl, 1,1-dimethyl-2-butynyl, 1,1-dimethyl-3-butynyl, 1,2-dimethyl-3-butynyl, 2,2-dimethyl-3-butynyl, 3,3-dimethyl-1-butynyl, 1-ethyl-2-butynyl, 1-ethyl-3-butynyl, 2-ethyl-3-butynyl and 1-ethyl-1-methyl-2-propynyl, especially propargyl and, in general and in particular, corresponding alkynyloxy and/or alkynylthio;

it being possible for these radicals to be substituted by one to five halogens and/or by one of the following: alkoxy, haloalkoxy, alkylthio and haloalkylthio as mentioned for R², especially fluorine, chlorine, methoxy, ethoxy, 1-methylethoxy, 1,1-dimethylethoxy, trifluoromethoxy, pentafluoroethoxy, methylthio, ethylthio, difluoromethylthio and pentafluoroethylthio, and phenyl, phenoxy or phenylthio;

cycloalkyl such as cyclopropyl, cyclobutyl, cyclopentyl and cyclohexyl, especially cyclopropyl, cyclopentyl and cyclohexyl, and corresponding cycloalkoxy and/or cycloalkylthio, especially cyclopentyloxy, cyclohexyloxy, cyclopentylthio, cyclohexylthio;

cycloalkenyl such as cyclopentenyl, cyclohexenyl, cyclohexadienyl, especially cyclopentenyl and cyclohexenyl, and corresponding cycloalkenyloxy and/or cycloalkenylthio, especially cyclopentenyloxy, cyclohexenyloxy, cyclopentenylthio and cyclohexenylthio;

phenyl, phenoxy, phenylthio, benzyl, benzyloxy and/or benzylthio, it being possible for these cyclic radicals to carry one to five halogens as mentioned for R², especially fluorine and chlorine, and/or one to three of the following: alkyl as mentioned for R¹, especially methyl, ethyl, propyl, iso-propyl;

haloalkyl as mentioned for R², especially trifluoromethyl, alkoxy as mentioned for R², especially methoxy, ethoxy, 1-methylethoxy and 1,1-dimethylethoxy;

haloalkoxy as mentioned for R², especially trifluoromethoxy and trifluoroethoxy and chloroethoxy; alkylthio as mentioned for R², especially methylthio and ethylthio; haloalkylthio as mentioned for R², especially difluoromethylthio and pentafluoroethylthio; phenyl, phenoxy, phenylthio, benzyl, benzyloxy and/or benzylthio;

in general and in particular the groups mentioned for R², or

NR⁷ R⁸ where

R⁷ and R⁸ are hydrogen; alkyl as mentioned for R², especially as mentioned in general for R¹ ; alkenyl, alkynyl or cycloalkyl of 3 to 6 carbons in each case, as mentioned in general and in particular for R³ ;

cycloalkenyl as mentioned in general and in particular for R³ ;

phenyl and/or benzyl, it being possible for the aromatic rings in turn to be substituted once to five times by the halogens mentioned for R³ and/or once to three times by alkyl, haloalkyl, alkoxy and/or haloalkoxy of 1 to 4 carbons in each case, as mentioned in general and in particular for R², or

R⁷ and R⁸ together are C₄ -C₆ -alkylene which can be interrupted by a hetero atom such as oxygen, sulfur or nitrogen, such as --(CH₂)₄ --, --(CH₂)₅ --, --(CH₂)₆ --, --(CH₂)₂ --O--(CH₂)₂ --, --(CH₂)₂ --S--(CH₂)₂ -- and --(CH₂)₂ --NH--(CH₂)₂ --, it being possible for these bridges in turn to carry one to three of the alkyl groups mentioned in general and in particular for R¹ ;

X is nitrogen or ═CR⁵ -- where R⁵ is in general and in particular one of the groups mentioned for R³,

n is 0 or 1 and

A is aryl or heteroaryl such as phenyl, naphthyl, six-membered heterocycles with one or more hetero atoms such as pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl, 1,3,5-triazinyl, 1,2,4-triazinyl, 1,2,3-triazinyl, tetrazinyl, five-membered heterocycles with one or more hetero atoms such as pyrrolyl, furyl, thienyl, pyrazolyl, imidazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, 1,2,3-triazolyl, 1,2,4-triazolyl, tetrazolyl, thiadiazolyl, fused heteroaryls such as indolyl, isoindolyl, thionaphthyl, quinolyl, isoquinolyl, cinnolinyl, phthalazinyl, quinazolyl, quinoxalyl, indazolyl, naphthyridinyl, benzothiazolyl, benzimidazolyl, benzofuryl, benzoxazolyl and benzotriazolyl, especially phenyl, naphthyl, thienyl, pyridyl, pyrazolyl, quinolyl, it being possible for these aromatic rings to carry one to five halogens, especially fluorine, chlorine and bromine, and/or one to three of the following: cyano, nitro, thiocyanato, --COR⁶ where R⁶ is hydroxyl, amino or one of the radicals R³, --SO_(m) R⁶ where m is 1 or 2, and/or the radicals mentioned for R³.

Particularly preferred sulfonamides are compounds of the general formula Ia ##STR10## where the substituents have the following meanings, in particular: R¹ is hydrogen or methyl;

R² is hydrogen or methyl, it being impossible, as a consequence of tautomerism, in the cases where R² is hydrogen to specify on which of the two nitrogens (N-7 or N-9) the hydrogen is located;

R³ and R⁴ are hydrogen, fluorine, chlorine, methyl, ethyl, n-propyl, iso-propyl, trifluoromethyl, methoxy, ethoxy, propoxy, 1-methylethoxy, methylthio, ethylthio, allyl, propargyl, allyloxy, allylthio, propargyloxy, propargylthio, trifluoromethoxy, methylamino, phenylamino, dimethylamino, pyrrolidino, piperidino, morpholino, 3,5-dimethylmorpholino, phenoxy, benzyloxy, phenylthio, benzylthio and/or phenyl;

A is phenyl, pyridyl, naphthyl, quinolyl, thienyl or pyrazolyl, it being possible for these aromatic radicals to carry one to three of the following, in particular: nitro, cyano, fluorine, chlorine, ethyl, propyl, isopropyl, trifluoromethyl, methoxy, ethoxy, 1-methylethoxy, 1,1-dimethylethoxy, trifluoromethoxy, trifluoroethoxy, chloroethoxy, methoxymethyl, ethoxymethyl, methoxyethyl, ethoxyethyl, methoxyethoxy, ethoxyethoxy, methylthio, ethylthio, methyl- and ethylsulfonyl, methoxycarbonyl, ethoxycarbonyl, iso-propoxycarbonyl, methyl- and ethylcarbonyl, N,N-dimethylsulfamoyl and N,N-dimethylcarbamoyl and the salts thereof.

The compounds Ib are additionally preferred, ##STR11## where R¹, R², R³ and R⁴ have the meaning stated for formula Ia, and the salts thereof.

Additional preferred compounds are sulfonamides of the general formula Ic ##STR12## where R¹, R², R³, R⁴ and A have the meaning stated for formula Ia, and R⁵ is hydrogen, methyl, fluorine or chlorine, and the salts thereof.

Additionally preferred are sulfonamides of the formula Id ##STR13## where R¹, R², R³, R⁴, R⁵ and A have the meaning given for formula Ic, and the salts thereof.

Examples of very active compounds of the formulae Ia, Ib, Ic and Id are listed in Tables I, II, III and IV which follow.

                                      TABLE I                                      __________________________________________________________________________      ##STR14##                         Ia                                          A               R.sup.1                                                                            R.sup.2                                                                           Pos.                                                                               R.sup.3                                                                             R.sup.4                                        __________________________________________________________________________     phenyl          H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       phenyl          H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       phenyl          H   H  7/9 Cl   CH.sub.3                                       phenyl          H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       phenyl          H   H  7/9 CH.sub.3                                                                            Cl                                             phenyl          H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             phenyl          H   H  7/9 Cl   Cl                                             phenyl          H   CH.sub.3                                                                          7   Cl   Cl                                             phenyl          H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      phenyl          H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      phenyl          H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      phenyl          H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      phenyl          H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       phenyl          H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       phenyl          H   H  7/9 Cl   OCH.sub.3                                      phenyl          H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      phenyl          H   H  7/9 OCH.sub.3                                                                           Cl                                             phenyl          H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-Cl-phenyl     H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-Cl-phenyl     H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-Cl-phenyl     H   H  7/9 Cl   CH.sub.3                                       2-Cl-phenyl     H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-Cl-phenyl     H   H  7/9 CH.sub.3                                                                            Cl                                             2-Cl-phenyl     H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-Cl-phenyl     H   H  7/9 Cl   Cl                                             2-Cl-phenyl     H   CH.sub.3                                                                          7   Cl   Cl                                             2-Cl-phenyl     H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-Cl-phenyl     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-Cl-phenyl     H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-Cl-phenyl     H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-Cl-phenyl     H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-Cl-phenyl     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-Cl-phenyl     H   H  7/9 Cl   OCH.sub.3                                      2-Cl-phenyl     H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-Cl-phenyl     H   H  7/9 OCH.sub.3                                                                           Cl                                             2-Cl-phenyl     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-Cl-phenyl     CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-Cl-phenyl     CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-Cl-phenyl     CH.sub.3                                                                           H  7/9 Cl   CH.sub.3                                       2-Cl-phenyl     CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-Cl-phenyl     CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            Cl                                             2-Cl-phenyl     CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-Cl-phenyl     CH.sub.3                                                                           H  7/9 Cl   Cl                                             2-Cl-phenyl     CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   Cl                                             2-Cl-phenyl     CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-Cl-phenyl     CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-Cl-phenyl     CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-Cl-phenyl     CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-Cl-phenyl     CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-Cl-phenyl     CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-Cl-phenyl     CH.sub.3                                                                           H  7/9 Cl   OCH.sub.3                                      2-Cl-phenyl     CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-Cl-phenyl     CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           Cl                                             2-Cl-phenyl     CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-Cl-phenyl     H   H  7/9 CF.sub.3                                                                            CF.sub.3                                       2-Cl-phenyl     H   CH.sub.3                                                                          7   CF.sub.3                                                                            CF.sub.3                                       2-Cl-phenyl     H   H  7/9 Cl   CF.sub.3                                       2-Cl-phenyl     H   CH.sub.3                                                                          7   Cl   CF.sub.3                                       2-Cl-phenyl     H   H  7/9 CF.sub.3                                                                            Cl                                             2-Cl-phenyl     H   CH.sub.3                                                                          7   CF.sub.3                                                                            Cl                                             2-Cl-phenyl     H   H  7/9 F    CF.sub.3                                       2-Cl-phenyl     H   CH.sub.3                                                                          7   F    CF.sub.3                                       2-Cl-phenyl     H   H  7/9 CF.sub.3                                                                            F                                              2-Cl-phenyl     H   CH.sub.3                                                                          7   CF.sub.3                                                                            F                                              2-Cl-phenyl     H   H  7/9 CH.sub.3                                                                            CF.sub.3                                       2-Cl-phenyl     H   CH.sub.3                                                                          7   CH.sub.3                                                                            CF.sub.3                                       2-Cl-phenyl     H   H  7/9 CF.sub.3                                                                            CH.sub.3                                       2-Cl-phenyl     H   CH.sub.3                                                                          7   CF.sub.3                                                                            CH.sub.3                                       2-Cl-phenyl     H   H  7/9 OCH.sub.3                                                                           CF.sub.3                                       2-Cl-phenyl     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CF.sub.3                                       2-Cl-phenyl     H   H  7/9 CF.sub.3                                                                            OCH.sub.3                                      2-Cl-phenyl     H   CH.sub.3                                                                          7   CF.sub.3                                                                            OCH.sub.3                                      2-Cl-phenyl     H   H  7/9 F    F                                              2-Cl-phenyl     H   CH.sub.3                                                                          7   F    F                                              2-Cl-phenyl     H   H  7/9 F    Cl                                             2-Cl-phenyl     H   CH.sub.3                                                                          7   F    Cl                                             2-Cl-phenyl     H   H  7/9 Cl   F                                              2-Cl-phenyl     H   CH.sub.3                                                                          7   Cl   F                                              2-Cl-phenyl     H   H  7/9 F    CH.sub.3                                       2-Cl-phenyl     H   CH.sub.3                                                                          7   F    CH.sub.3                                       2-Cl-phenyl     H   H  7/9 CH.sub.3                                                                            F                                              2-Cl-phenyl     H   CH.sub.3                                                                          7   CH.sub.3                                                                            F                                              2-Cl-phenyl     H   H  7/9 F    OCH.sub.3                                      2-Cl-phenyl     H   CH.sub.3                                                                          7   F    OCH.sub.3                                      2-Cl-phenyl     H   H  7/9 OCH.sub.3                                                                           F                                              2-Cl-phenyl     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           F                                              2-Cl-phenyl     H   H  7/9 N(CH.sub.3).sub.2                                                                   Cl                                             2-Cl-phenyl     H   CH.sub.3                                                                          7   N(CH.sub.3).sub.2                                                                   Cl                                             2-Cl-phenyl     H   H  7/9 SCH.sub. 3                                                                          Cl                                             2-Cl-phenyl     H   CH.sub.3                                                                          7   SCH.sub.3                                                                           Cl                                             2-F-phenyl      H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-F-phenyl      H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-F-phenyl      H   H  7/9 Cl   CH.sub.3                                       2-F-phenyl      H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-F-phenyl      H   H  7/9 CH.sub.3                                                                            Cl                                             2-F-phenyl      H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-F-phenyl      H   H  7/9 Cl   Cl                                             2-F-phenyl      H   CH.sub.3                                                                          7   Cl   Cl                                             2-F-phenyl      H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-F-phenyl      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-F-phenyl      H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-F-phenyl      H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-F-phenyl      H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-F-phenyl      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-F-phenyl      H   H  7/9 Cl   OCH.sub.3                                      2-F-phenyl      H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-F-phenyl      H   H  7/9 OCH.sub.3                                                                           Cl                                             2-F-phenyl      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-Br-phenyl     H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-Br-phenyl     H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-Br-phenyl     H   H  7/9 Cl   CH.sub.3                                       2-Br-phenyl     H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-Br-phenyl     H   H  7/9 CH.sub.3                                                                            Cl                                             2-Br-phenyl     H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-Br-phenyl     H   H  7/9 Cl   Cl                                             2-Br-phenyl     H   CH.sub.3                                                                          7   Cl   Cl                                             2-Br-phenyl     H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-Br-phenyl     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-Br-phenyl     H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-Br-phenyl     H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-Br-phenyl     H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-Br-phenyl     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-Br-phenyl     H   H  7/9 Cl   OCH.sub.3                                      2-Br-phenyl     H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-Br-phenyl     H   H  7/9 OCH.sub.3                                                                           Cl                                             2-Br-phenyl     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CN-phenyl     H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CN-phenyl     H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CN-phenyl     H   H  7/9 Cl   CH.sub.3                                       2-CN-phenyl     H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CN-phenyl     H   H  7/9 CH.sub.3                                                                            Cl                                             2-CN-phenyl     H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CN-phenyl     H   H  7/9 Cl   Cl                                             2-CN-phenyl     H   CH.sub.3                                                                          7   Cl   Cl                                             2-CN-phenyl     H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CN-phenyl     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CN-phenyl     H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CN-phenyl     H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CN-phenyl     H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CN-phenyl     H   CH.sub.3                                                                          7   OCH.sub. 3                                                                          CH.sub.3                                       2-CN-phenyl     H   H  7/9 Cl   OCH.sub.3                                      2-CN-phenyl     H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CN-phenyl     H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CN-phenyl     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CF.sub.3 -phenyl                                                                             H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CF.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CF.sub.3 -phenyl                                                                             H   H  7/9 Cl   CH.sub.3                                       2-CF.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CF.sub.3 -phenyl                                                                             H   H  7/9 CH.sub.3                                                                            Cl                                             2-CF.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CF.sub.3 -phenyl                                                                             H   H  7/9 Cl   Cl                                             2-CF.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   Cl   Cl                                             2-CF.sub.3 -phenyl                                                                             H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CF.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CF.sub.3 -phenyl                                                                             H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CF.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CF.sub.3 -phenyl                                                                             H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CF.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CF.sub.3 -phenyl                                                                             H   H  7/9 Cl   OCH.sub.3                                      2-CF.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CF.sub.3 -phenyl                                                                             H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CF.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-NO.sub.2 -phenyl                                                                             H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-NO.sub.2 -phenyl                                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-NO.sub.2 -phenyl                                                                             H   H  7/9 Cl   CH.sub.3                                       2-NO.sub.2 -phenyl                                                                             H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-NO.sub.2 -phenyl                                                                             H   H  7/9 CH.sub.3                                                                            Cl                                             2-NO.sub.2 -phenyl                                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-NO.sub.2 -phenyl                                                                             H   H  7/9 Cl   Cl                                             2-NO.sub.2 -phenyl                                                                             H   CH.sub.3                                                                          7   Cl   Cl                                             2-NO.sub.2 -phenyl                                                                             H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-NO.sub.2 -phenyl                                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-NO.sub.2 -phenyl                                                                             H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-NO.sub.2 -phenyl                                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-NO.sub.2 -phenyl                                                                             H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-NO.sub.2 -phenyl                                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-NO.sub.2 -phenyl                                                                             H   H  7/9 Cl   OCH.sub.3                                      2-NO.sub.2 -phenyl                                                                             H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-NO.sub.2 -phenyl                                                                             H   H  7/9 OCH.sub.3                                                                           Cl                                             2-NO.sub.2 -phenyl                                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CH.sub.3 -phenyl                                                                             H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CH.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CH.sub.3 -phenyl                                                                             H   H  7/9 Cl   CH.sub.3                                       2-CH.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CH.sub.3 -phenyl                                                                             H   H  7/9 CH.sub.3                                                                            Cl                                             2-CH.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CH.sub.3 -phenyl                                                                             H   H  7/9 Cl   Cl                                             2-CH.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   Cl   Cl                                             2-CH.sub.3 -phenyl                                                                             H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CH.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CH.sub.3 -phenyl                                                                             H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CH.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CH.sub.3 -phenyl                                                                             H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CH.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CH.sub.3 -phenyl                                                                             H   H  7/9 Cl   OCH.sub.3                                      2-CH.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CH.sub.3 -phenyl                                                                             H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CH.sub.3 -phenyl                                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 Cl   Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   Cl   Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           H  7/9 Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           H  7/9 Cl   Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           H  7/9 Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 CF.sub.3                                                                            CF.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   CF.sub.3                                                                            CF.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 Cl   CF.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   Cl   CF.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 CF.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   CF.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 F    CF.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   F    CF.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 CF.sub.3                                                                            F                                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   CF.sub.3                                                                            F                                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 CH.sub.3                                                                            CF.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   CH.sub.3                                                                            CF.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 CF.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   CF.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 OCH.sub.3                                                                           CF.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CF.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 CF.sub.3                                                                            OCH.sub.3                                      2-CO.sub. 2 CH.sub.3 -phenyl                                                                   H   CH.sub.3                                                                          7   CF.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 F    F                                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   F    F                                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 F    Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   F    Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 Cl   F                                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   Cl   F                                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 F    CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   F    CH.sub.3                                       2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 CH.sub.3                                                                            F                                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   CH.sub.3                                                                            F                                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 F    OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   F    OCH.sub.3                                      2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 OCH.sub.3                                                                           F                                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   OCH.sub.3                                                                           F                                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 N(CH.sub.3).sub.2                                                                   Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   N(CH.sub.3).sub.2                                                                   Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 SCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   SCH.sub.3                                                                           Cl                                             2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   H  7/9 Cl   CH.sub.3                                       2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   H  7/9 CH.sub.3                                                                            Cl                                             2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   H  7/9 Cl   Cl                                             2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   CH.sub.3                                                                          7   Cl   Cl                                             2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 C.sub. 2 H.sub.5 -phenyl                                                            H   H  7/9 Cl   OCH.sub.3                                      2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   H  7/9 Cl   CH.sub.3                                       2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   H  7/9 CH.sub.3                                                                            Cl                                             2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   H  7/9 Cl   Cl                                             2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   CH.sub.3                                                                          7   Cl   Cl                                             2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   H  7/9 Cl   OCH.sub.3                                      2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CON(CH.sub.3).sub.2 -phenyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-COCH.sub.3 -phenyl                                                                           H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-COCH.sub.3 -phenyl                                                                           H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-COCH.sub.3 -phenyl                                                                           H   H  7/9 Cl   CH.sub.3                                       2-COCH.sub.3 -phenyl                                                                           H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-COCH.sub.3 -phenyl                                                                           H   H  7/9 CH.sub.3                                                                            Cl                                             2-COCH.sub.3 -phenyl                                                                           H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-COCH.sub.3 -phenyl                                                                           H   H  7/9 Cl   Cl                                             2-COCH.sub.3 -phenyl                                                                           H   CH.sub.3                                                                          7   Cl   Cl                                             2-COCH.sub.3 -phenyl                                                                           H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-COCH.sub.3 -phenyl                                                                           H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-COCH.sub.3 -phenyl                                                                           H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-COCH.sub.3 -phenyl                                                                           H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-COCH.sub.3 -phenyl                                                                           H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-COCH.sub.3 -phenyl                                                                           H   CH.sub.3                                                                          7   OCH.sub. 3                                                                          CH.sub.3                                       2-COCH.sub.3 -phenyl                                                                           H   H  7/9 Cl   OCH.sub.3                                      2-COCH.sub.3 -phenyl                                                                           H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-COCH.sub.3 -phenyl                                                                           H   H  7/9 OCH.sub.3                                                                           Cl                                             2-COCH.sub.3 -phenyl                                                                           H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-OCH.sub.3 -phenyl                                                                            H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub.3 -phenyl                                                                            H   H  7/9 Cl   CH.sub.3                                       2-OCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-OCH.sub.3 -phenyl                                                                            H   H  7/9 CH.sub.3                                                                            Cl                                             2-OCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-OCH.sub.3 -phenyl                                                                            H   H  7/9 Cl   Cl                                             2-OCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   Cl   Cl                                             2-OCH.sub.3 -phenyl                                                                            H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.3 -phenyl                                                                            H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.3 -phenyl                                                                            H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.3 -phenyl                                                                            H   H  7/9 Cl   OCH.sub.3                                      2-OCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-OCH.sub. 3 -phenyl                                                                           H   H  7/9 OCH.sub.3                                                                           Cl                                             2-OCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   H  7/9 Cl   CH.sub.3                                       2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   H  7/9 CH.sub.3                                                                            Cl                                             2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   H  7/9 Cl   Cl                                             2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   Cl   Cl                                             2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   H  7/9 Cl   OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   H  7/9 OCH.sub.3                                                                           Cl                                             2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 Cl   CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 CH.sub.3                                                                            Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 Cl   Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   Cl   Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 Cl   OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 OCH.sub.3                                                                           Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           H  7/9 Cl   CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           H  7/9 Cl   Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           H  7/9 Cl   OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 CF.sub.3                                                                            CF.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   CF.sub.3                                                                            CF.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 Cl   CF.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   Cl   CF.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 CF.sub.3                                                                            Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   CF.sub.3                                                                            Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 F    CF.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub. 3                                                                         7   F    CF.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 CF.sub.3                                                                            F                                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   CF.sub.3                                                                            F                                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 CH.sub.3                                                                            CF.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            CF.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 CF.sub.3                                                                            CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   CF.sub.3                                                                            CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 OCH.sub.3                                                                           CF.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CF.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 CF.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   CF.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 F    F                                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   F    F                                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 F    Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   F    Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 Cl   F                                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   Cl   F                                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 F    CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   F    CH.sub.3                                       2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 CH.sub.3                                                                            F                                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            F                                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 F    OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   F    OCH.sub.3                                      2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 OCH.sub.3                                                                           F                                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           F                                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 N(CH.sub.3).sub.2                                                                   Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   N(CH.sub.3).sub.2                                                                   Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   H  7/9 SCH.sub.3                                                                           Cl                                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H   CH.sub.3                                                                          7   SCH.sub.3                                                                           Cl                                             2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   H  7/9 Cl   CH.sub.3                                       2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   H  7/9 CH.sub. 3                                                                           Cl                                             2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   H  7/9 Cl   Cl                                             2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   CH.sub.3                                                                          7   Cl   Cl                                             2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   H  7/9 Cl   OCH.sub.3                                      2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   H  7/9 OCH.sub.3                                                                           Cl                                             2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                          H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-SCH.sub.3 -phenyl                                                                            H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-SCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   CH.sub. 3                                                                           CH.sub.3                                       2-SCH.sub.3 -phenyl                                                                            H   H  7/9 Cl   CH.sub.3                                       2-SCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-SCH.sub.3 -phenyl                                                                            H   H  7/9 CH.sub.3                                                                            Cl                                             2-SCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-SCH.sub.3 -phenyl                                                                            H   H  7/9 Cl   Cl                                             2-SCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   Cl   Cl                                             2-SCH.sub.3 -phenyl                                                                            H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-SCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-SCH.sub.3 -phenyl                                                                            H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-SCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-SCH.sub.3 -phenyl                                                                            H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-SCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-SCH.sub.3 -phenyl                                                                            H   H  7/9 Cl   OCH.sub.3                                      2-SCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-SCH.sub.3 -phenyl                                                                            H   H  7/9 OCH.sub.3                                                                           Cl                                             2-SCH.sub.3 -phenyl                                                                            H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 Cl   CH.sub.3                                       2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 CH.sub.3                                                                            Cl                                             2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 Cl   Cl                                             2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   Cl   Cl                                             2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 Cl   OCH.sub.3                                      2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   H  7/9 OCH.sub.3                                                                           Cl                                             2-SO.sub.2 CH.sub.3 -phenyl                                                                    H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub. 3                                      2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   H  7/9 Cl   CH.sub.3                                       2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   H  7/9 CH.sub.3                                                                            Cl                                             2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   H  7/9 Cl   Cl                                             2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   CH.sub.3                                                                          7   Cl   Cl                                             2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   H  7/9 Cl   OCH.sub.3                                      2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   H  7/9 OCH.sub.3                                                                           Cl                                             2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                           H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2,6-Cl,Cl-phenyl                                                                               H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   H  7/9 Cl   CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   H  7/9 CH.sub.3                                                                            Cl                                             2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2,6-Cl,Cl-phenyl                                                                               H   H  7/9 Cl   Cl                                             2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   Cl   Cl                                             2,6-Cl,Cl-phenyl                                                                               H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   H  7/9 Cl   OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               H   H  7/9 OCH.sub.3                                                                           Cl                                             2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 Cl   CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               CH.sub. 3                                                                          H  7/9 CH.sub.3                                                                            Cl                                             2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 Cl   Cl                                             2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   Cl                                             2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 Cl   OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           Cl                                             2,6-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2,6-Cl,Cl-phenyl                                                                               H   H  7/9 CF.sub.3                                                                            CF.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CF.sub.3                                                                            CF.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   H  7/9 Cl   CF.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   Cl   CF.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   H  7/9 CF.sub.3                                                                            Cl                                             2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CF.sub.3                                                                            Cl                                             2,6-Cl,Cl-phenyl                                                                               H   H  7/9 F    CF.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   F    CF.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   H  7/9 CF.sub.3                                                                            F                                              2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CF.sub.3                                                                            F                                              2,6-Cl,Cl-phenyl                                                                               H   H  7/9 CH.sub.3                                                                            CF.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            CF.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   H  7/9 CF.sub.3                                                                            CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CF.sub.3                                                                            CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   H  7/9 OCH.sub.3                                                                           CF.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CF.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   H  7/9 CF.sub.3                                                                            OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CF.sub.3                                                                            OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               H   H  7/9 F    F                                              2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   F    F                                              2,6-Cl,Cl-phenyl                                                                               H   H  7/9 F    Cl                                             2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   F    Cl                                             2,6-Cl,Cl-phenyl                                                                               H   H  7/9 Cl   F                                              2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   Cl   F                                              2,6-Cl,Cl-phenyl                                                                               H   H  7/9 F    CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   F    CH.sub.3                                       2,6-Cl,Cl-phenyl                                                                               H   H  7/9 CH.sub.3                                                                            F                                              2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            F                                              2,6-Cl,Cl-phenyl                                                                               H   H  7/9 F    OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   F    OCH.sub.3                                      2,6-Cl,Cl-phenyl                                                                               H   H  7/9 OCH.sub.3                                                                           F                                              2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           F                                              2,6-Cl,Cl-phenyl                                                                               H   H  7/9 N(CH.sub.3).sub.2                                                                   Cl                                             2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   N(CH.sub.3).sub.2                                                                   Cl                                             2,6-Cl,Cl-phenyl                                                                               H   H  7/9 SCH.sub.3                                                                           Cl                                             2,6-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   SCH.sub.3                                                                           Cl                                             2-Cl,6-CH.sub. 3 -phenyl                                                                       H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 Cl   CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 CH.sub.3                                                                            Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 Cl   Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 Cl   OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           H  7/9 Cl   CH.sub.3                                       2-Cl,6-CH.sub. 3 -phenyl                                                                       CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           H  7/9 Cl   Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           H  7/9 Cl   OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 CF.sub.3                                                                            CF.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CF.sub.3                                                                            CF.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 Cl   CF.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   CF.sub. 3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 CF.sub.3                                                                            Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CF.sub.3                                                                            Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 F    CF.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   F    CF.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 CF.sub.3                                                                            F                                              2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CF.sub.3                                                                            F                                              2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 CH.sub.3                                                                            CF.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            CF.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 CF.sub.3                                                                            CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CF.sub.3                                                                            CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           CF.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CF.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 CF.sub.3                                                                            OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CF.sub.3                                                                            OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 F    F                                              2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   F    F                                              2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 F    Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   F    Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 Cl   F                                              2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   F                                              2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 F    CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   F    CH.sub.3                                       2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 CH.sub.3                                                                            F                                              2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            F                                              2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 F    OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   F    OCH.sub.3                                      2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           F                                              2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           F                                              2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 N(CH.sub.3).sub.2                                                                   Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   N(CH.sub.3).sub.2                                                                   Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        H   H  7/9 SCH.sub.3                                                                           Cl                                             2-Cl,6-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   SCH.sub.3                                                                           Cl                                             2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 Cl   CH.sub.3                                       2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 CH.sub.3                                                                            Cl                                             2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 Cl   Cl                                             2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   Cl   Cl                                             2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 Cl   OCH.sub.3                                      2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 OCH.sub.3                                                                           Cl                                             2-Cl,6-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-Cl,6-OCH.sub.3 -phenyl                                                                       H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-Cl,6-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-Cl,6-OCH.sub.3 -phenyl                                                                       H   H  7/9 Cl   CH.sub.3                                       2-Cl,6-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-Cl,6-OCH.sub.3 -phenyl                                                                       H   H  7/9 CH.sub.3                                                                            Cl                                             2-Cl,6-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-Cl,6-OCH.sub.3 -phenyl                                                                       H   H  7/9 Cl   Cl                                             2-Cl,6-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   Cl   Cl                                             2-Cl,6-OCH.sub.3 -phenyl                                                                       H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,6-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,6-OCH.sub.3 -phenyl                                                                       H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-Cl,6-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-Cl,6-OCH.sub.3 -phenyl                                                                       H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-Cl,6-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-Cl,6-OCH.sub.3 -phenyl                                                                       H   H  7/9 Cl   OCH.sub.3                                      2-Cl,6-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-Cl,6-OCH.sub.3 -phenyl                                                                       H   H  7/9 OCH.sub.3                                                                           Cl                                             2-Cl,6-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   H  7/9 Cl   CH.sub.3                                       2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   H  7/9 CH.sub.3                                                                            Cl                                             2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   H  7/9 Cl   Cl                                             2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   CH.sub.3                                                                          7   Cl   Cl                                             2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   H  7/9 Cl   OCH.sub.3                                      2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   H  7/9 OCH.sub.3                                                                           Cl                                             2-OCH.sub.3,6-CO.sub.2 CH.sub.3 -phenyl                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   H  7/9 Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   H  7/9 CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   H  7/9 Cl   Cl                                             2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   Cl   Cl                                             2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   H  7/9 Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,6-CH.sub.3 -phenyl                                                         H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2,5-Cl,Cl-phenyl                                                                               H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   H  7/9 Cl   CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   H  7/9 CH.sub.3                                                                            Cl                                             2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2,5-Cl,Cl-phenyl                                                                               H   H  7/9 Cl   Cl                                             2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   Cl   Cl                                             2,5-Cl,Cl-phenyl                                                                               H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   H  7/9 Cl   OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               H   H  7/9 OCH.sub.3                                                                           Cl                                             2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 Cl   CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            Cl                                             2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 Cl   Cl                                             2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   Cl                                             2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 Cl   OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           Cl                                             2,5-Cl,Cl-phenyl                                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2,5-Cl,Cl-phenyl                                                                               H   H  7/9 CF.sub.3                                                                            CF.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CF.sub.3                                                                            CF.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   H  7/9 Cl   CF.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   Cl   CF.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   H  7/9 CF.sub.3                                                                            Cl                                             2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CF.sub.3                                                                            Cl                                             2,5-Cl,Cl-phenyl                                                                               H   H  7/9 F    CF.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   F    CF.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   H  7/9 CF.sub.3                                                                            F                                              2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CF.sub.3                                                                            F                                              2,5-Cl,Cl-phenyl                                                                               H   H  7/9 CH.sub.3                                                                            CF.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            CF.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   H  7/9 CF.sub.3                                                                            CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CF.sub.3                                                                            CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   H  7/9 OCH.sub.3                                                                           CF.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CF.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   H  7/9 CF.sub.3                                                                            OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CF.sub.3                                                                            OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               H   H  7/9 F    F                                              2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   F    F                                              2,5-Cl,Cl-phenyl                                                                               H   H  7/9 F    Cl                                             2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   F    Cl                                             2,5-Cl,Cl-phenyl                                                                               H   H  7/9 Cl   F                                              2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   Cl   F                                              2,5-Cl,Cl-phenyl                                                                               H   H  7/9 F    CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   F    CH.sub.3                                       2,5-Cl,Cl-phenyl                                                                               H   H  7/9 CH.sub.3                                                                            F                                              2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            F                                              2,5-Cl,Cl-phenyl                                                                               H   H  7/9 F    OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   F    OCH.sub.3                                      2,5-Cl,Cl-phenyl                                                                               H   H  7/9 OCH.sub.3                                                                           F                                              2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           F                                              2,5-Cl,Cl-phenyl                                                                               H   H  7/9 N(CH.sub.3).sub.2                                                                   Cl                                             2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   N(CH.sub.3).sub.2                                                                   Cl                                             2,5-Cl,Cl-phenyl                                                                               H   H  7/9 SCH.sub.3                                                                           Cl                                             2,5-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   SCH.sub.3                                                                           Cl                                             2-OCH.sub.3,5-Br-phenyl                                                                        H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub.3,5-Br-phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-OCH.sub. 3,5-Br-phenyl                                                                       H   H  7/9 Cl   CH.sub.3                                       2-OCH.sub.3,5-Br-phenyl                                                                        H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-OCH.sub.3,5-Br-phenyl                                                                        H   H  7/9 CH.sub.3                                                                            Cl                                             2-OCH.sub.3,5-Br-phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-OCH.sub.3,5-Br-phenyl                                                                        H   H  7/9 Cl   Cl                                             2-OCH.sub.3,5-Br-phenyl                                                                        H   CH.sub.3                                                                          7   Cl   Cl                                             2-OCH.sub.3,5-Br-phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.3,5-Br-phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-OCH.sub.3,5-Br-phenyl                                                                        H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.3,5-Br-phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-OCH.sub.3,5-Br-phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.3,5-Br-phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-OCH.sub.3,5-Br-phenyl                                                                        H   H  7/9 Cl   OCH.sub.3                                      2-OCH.sub.3,5-Br-phenyl                                                                        H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-OCH.sub.3,5-Br-phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           Cl                                             2-OCH.sub.3,5-Br-phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   H  7/9 CH.sup.3                                                                            CH.sup.3                                       2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   CH.sup.3                                                                          7   CH.sup.3                                                                            CH.sup.3                                       2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   H  7/9 Cl   CH.sup.3                                       2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   CH.sup.3                                                                          7   Cl   CH.sup.3                                       2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   H  7/9 CH.sup.3                                                                            Cl                                             2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   CH.sup.3                                                                          7   CH.sup.3                                                                            Cl                                             2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   H  7/9 Cl   Cl                                             2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   CH.sup.3                                                                          7   Cl   Cl                                             2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   H  7/9 OCH.sup.3                                                                           OCH.sup.3                                      2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   CH.sup.3                                                                          7   OCH.sup.3                                                                           OCH.sup.3                                      2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   H  7/9 CH.sup.3                                                                            OCH.sup.3                                      2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   CH.sup.3                                                                          7   CH.sup.3                                                                            OCH.sup.3                                      2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   H  7/9 OCH.sup.3                                                                           CH.sup.3                                       2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   CH.sup.3                                                                          7   OCH.sup.3                                                                           CH.sup.3                                       2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   H  7/9 Cl   OCH.sup.3                                      2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   CH.sup.3                                                                          7   Cl   OCH.sup.3                                      2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   H  7/9 OCH.sup.3                                                                           Cl                                             2,5-Di-OCH.sub.2 CF.sub.3 -phenyl                                                              H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2,5-Di-OCH.sub.3 -phenyl                                                                       H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2,5-Di-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2,5-Di-OCH.sub.3 -phenyl                                                                       H   H  7/9 Cl   CH.sub.3                                       2,5-Di-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2,5-Di-OCH.sub.3 -phenyl                                                                       H   H  7/9 CH.sub.3                                                                            Cl                                             2,5-Di-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2,5-Di-OCH.sub.3 -phenyl                                                                       H   H  7/9 Cl   Cl                                             2,5-Di-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   Cl   Cl                                             2,5-Di-OCH.sub.3 -phenyl                                                                       H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2,5-Di-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2,5-Di-OCH.sub.3 -phenyl                                                                       H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2,5-Di-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2,5-Di-OCH.sub.3 -phenyl                                                                       H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2,5-Di-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2,5-Di-OCH.sub.3 -phenyl                                                                       H   H  7/9 Cl   OCH.sub.3                                      2,5-Di-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2,5-Di-OCH.sub.3 -phenyl                                                                       H   H  7/9 OCH.sub.3                                                                           Cl                                             2,5-Di-OCH.sub.3 -phenyl                                                                       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 Cl   CH.sub.3                                       2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 CH.sub.3                                                                            Cl                                             2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 Cl   Cl                                             2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   Cl   Cl                                             2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 Cl   OCH.sub.3                                      2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   H  7/9 OCH.sub.3                                                                           Cl                                             2-Cl,5-CO.sub.2 CH.sub.3 -phenyl                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   H  7/9 Cl   CH.sub.3                                       2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   H  7/9 CH.sub.3                                                                            Cl                                             2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   H  7/9 Cl   Cl                                             2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   CH.sub.3                                                                          7   Cl   Cl                                             2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   H  7/9 Cl   OCH.sub.3                                      2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CH.sub.3,5-OCH.sub.3 -phenyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-Cl,5-NO.sub.2 -phenyl                                                                        H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-Cl,5-NO.sub.2 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-Cl,5-NO.sub.2 -phenyl                                                                        H   H  7/9 Cl   CH.sub. 3                                      2-Cl,5-NO.sub.2 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-Cl,5-NO.sub.2 -phenyl                                                                        H   H  7/9 CH.sub.3                                                                            Cl                                             2-Cl,5-NO.sub.2 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-Cl,5-NO.sub.2 -phenyl                                                                        H   H  7/9 Cl   Cl                                             2-Cl,5-NO.sub.2 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   Cl                                             2-Cl,5-NO.sub.2 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,5-NO.sub.2 -phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,5-NO.sub.2 -phenyl                                                                        H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-Cl,5-NO.sub.2 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-Cl,5-NO.sub.2 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-Cl,5-NO.sub.2 -phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-Cl,5-NO.sub.2 -phenyl                                                                        H   H  7/9 Cl   OCH.sub.3                                      2-Cl,5-NO.sub.2 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-Cl,5-NO.sub.2 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           Cl                                             2-Cl,5-NO.sub.2 -phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-Cl,5-CH.sub.3 -phenyl                                                                        H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-Cl,5-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-Cl,5-CH.sub.3 -phenyl                                                                        H   H  7/9 Cl   CH.sub.3                                       2-Cl,5-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-Cl,5-CH.sub.3 -phenyl                                                                        H   H  7/9 CH.sub.3                                                                            Cl                                             2-Cl,5-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-Cl,5-CH.sub.3 -phenyl                                                                        H   H  7/9 Cl   Cl                                             2-Cl,5-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   Cl                                             2-Cl,5-CH.sub.3 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,5-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,5-CH.sub.3 -phenyl                                                                        H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-Cl,5-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-Cl,5-CH.sub.3 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-Cl,5-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-Cl,5-CH.sub.3 -phenyl                                                                        H   H  7/9 Cl   OCH.sub.3                                      2-Cl,5-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-Cl,5-CH.sub.3 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           Cl                                             2-Cl,5-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2,5-Di-CH.sub.3 -phenyl                                                                        H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2,5-Di-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2,5-Di-CH.sub.3 -phenyl                                                                        H   H  7/9 Cl   CH.sub.3                                       2,5-Di-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2,5-Di-CH.sub.3 -phenyl                                                                        H   H  7/9 CH.sub.3                                                                            Cl                                             2,5-Di-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2,5-Di-CH.sub.3 -phenyl                                                                        H   H  7/9 Cl   Cl                                             2,5-Di-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   Cl                                             2,5-Di-CH.sub.3 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2,5-Di-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2,5-Di-CH.sub.3 -phenyl                                                                        H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2,5-Di-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2,5-Di-CH.sub.3 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2,5-Di-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2,5-Di-CH.sub.3 -phenyl                                                                        H   H  7/9 Cl   OCH.sub.3                                      2,5-Di-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2,5-Di-CH.sub.3 -phenyl                                                                        H   H  7/9 OCH.sub.3                                                                           Cl                                             2,5-Di-CH.sub.3 -phenyl                                                                        H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2,3-Cl,Cl-phenyl                                                                               H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2,3-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2,3-Cl,Cl-phenyl                                                                               H   H  7/9 Cl   CH.sub.3                                       2,3-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2,3-Cl,Cl-phenyl                                                                               H   H  7/9 CH.sub.3                                                                            Cl                                             2,3-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2,3-Cl,Cl-phenyl                                                                               H   H  7/9 Cl   Cl                                             2,3-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   Cl   Cl                                             2,3-Cl,Cl-phenyl                                                                               H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2,3-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2,3-Cl,Cl-phenyl                                                                               H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2,3-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2,3-Cl,Cl-phenyl                                                                               H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2,3-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2,3-Cl,Cl-phenyl                                                                               H   H  7/9 Cl   OCH.sub.3                                      2,3-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2,3-Cl,Cl-phenyl                                                                               H   H  7/9 OCH.sub.3                                                                           Cl                                             2,3-Cl,Cl-phenyl                                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   H  7/9 Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   H  7/9 CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   H  7/9 Cl   Cl                                             2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   CH.sub.3                                                                          7   Cl   Cl                                             2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   H  7/9 Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-Cl-phenyl                                                                H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   H  7/9 Cl   CH.sub.3                                       2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   H  7/9 CH.sub.3                                                                            Cl                                             2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   H  7/9 Cl   Cl                                             2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   CH.sub.3                                                                          7   Cl   Cl                                             2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CON(CH.sub. 3).sub.2,3-Cl-phenyl                                                             H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   H  7/9 Cl   OCH.sub.3                                      2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CON(CH.sub.3).sub.2,3-Cl-phenyl                                                              H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 Cl   Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   Cl   Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub. 2 CH.sub.3,3-F-phenyl                                                                H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           H  7/9 Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           H  7/9 Cl   Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3 ,3-F-phenyl                                                                CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           H  7/9 Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 CF.sub.3                                                                            CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   CF.sub.3                                                                            CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 Cl   CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   Cl   CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 CF.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   CF.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 F    CF.sub.3                                       2-CO.sub.2 CH.sub.3 ,3-F-phenyl                                                                H   CH.sub.3                                                                          7   F    CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 CF.sub.3                                                                            F                                              2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   CF.sub.3                                                                            F                                              2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 CH.sub.3                                                                            CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 CF.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   CF.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 OCH.sub.3                                                                           CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 CF.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   CF.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 F    F                                              2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   F    F                                              2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 F    Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   F    Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 Cl   F                                              2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   Cl   F                                              2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 F    CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   F    CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 CH.sub.3                                                                            F                                              2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            F                                              2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 F    OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   F    OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 OCH.sub.3                                                                           F                                              2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           F                                              2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 N(CH.sub.3).sub.2                                                                   Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   N(CH.sub.3).sub.2                                                                   Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   H  7/9 SCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                 H   CH.sub.3                                                                          7   SCH.sub.3                                                                           Cl                                             2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   H  7/9 Cl   CH.sub.3                                       2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   H  7/9 CH.sub.3                                                                            Cl                                             2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   H  7/9 Cl   Cl                                             2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   CH.sub.3                                                                          7   Cl   Cl                                             2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   H  7/9 Cl   OCH.sub.3                                      2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CON(CH.sub.3).sub.2,3-F-phenyl                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            CH.sub.3                                       2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           H  7/9 Cl   CH.sub.3                                       2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   CH.sub.3                                       2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            Cl                                             2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub. 3                                                                           Cl                                             2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           H  7/9 Cl   Cl                                             2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   Cl                                             2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           H  7/9 Cl   OCH.sub.3                                      2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           Cl                                             2,5,6-Cl,Cl,Cl-phenyl                                                                          CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2,5,6-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2,5,6-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2,5,6-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 Cl   CH.sub.3                                       2,5,6-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2,5,6-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 CH.sub.3                                                                            Cl                                             2,5,6-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2,5,6-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 Cl   Cl                                             2,5,6-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   Cl   Cl                                             2,5,6-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2,5,6-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2,5,6-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2,5,6-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2,5,6-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2,5,6-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2,5,6-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 Cl   OCH.sub.3                                      2,5,6-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2,5,6-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 OCH.sub.3                                                                           Cl                                             2,5,6-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2,3,5-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2,3,5-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2,3,5-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 Cl   CH.sub.3                                       2,3,5-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2,3,5-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 CH.sub.3                                                                            Cl                                             2,3,5-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2,3,5-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 Cl   Cl                                             2,3,5-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   Cl   Cl                                             2,3,5-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2,3,5-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2,3,5-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2,3,5-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2,3,5-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2,3,5-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2,3,5-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 Cl   OCH.sub.3                                      2,3,5-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2,3,5-Cl,Cl,Cl-phenyl                                                                          H   H  7/9 OCH.sub.3                                                                           Cl                                             2,3,5-Cl,Cl,Cl-phenyl                                                                          H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             1-naphthyl      H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       1-naphthyl      H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       1-naphthyl      H   H  7/9 Cl   CH.sub.3                                       1-naphthyl      H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       1-naphthyl      H   H  7/9 CH.sub.3                                                                            Cl                                             1-naphthyl      H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             1-naphthyl      H   H  7/9 Cl   Cl                                             1-naphthyl      H   CH.sub.3                                                                          7   Cl   Cl                                             1-naphthyl      H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      1-naphthyl      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      1-naphthyl      H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      1-naphthyl      H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      1-naphthyl      H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       1-naphthyl      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       1-naphthyl      H   H  7/9 Cl   OCH.sub.3                                      1-naphthyl      H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      1-naphthyl      H   H  7/9 OCH.sub.3                                                                           Cl                                             1-naphthyl      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             8-Cl,1-naphthyl H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       8-Cl,1-naphthyl H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       8-Cl,1-naphthyl H   H  7/9 Cl   CH.sub.3                                       8-Cl,1-naphthyl H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       8-Cl,1-naphthyl H   H  7/9 CH.sub.3                                                                            Cl                                             8-Cl,1-naphthyl H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             8-Cl,1-naphthyl H   H  7/9 Cl   Cl                                             8-Cl,1-naphthyl H   CH.sub.3                                                                          7   Cl   Cl                                             8-Cl,1-naphthyl H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      8-Cl,1-naphthyl H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      8-Cl,1-naphthyl H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      8-Cl,1-naphthyl H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      8-Cl,1-naphthyl H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       8-Cl,1-naphthyl H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       8-Cl,1-naphthyl H   H  7/9 Cl   OCH.sub.3                                      8-Cl,1-naphthyl H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      8-Cl,1-naphthyl H   H  7/9 OCH.sub.3                                                                           Cl                                             8-Cl,1-naphthyl H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 Cl   CH.sub.3                                       8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 CH.sub.3                                                                            Cl                                             8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 Cl   Cl                                             8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   Cl   Cl                                             8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 CH.sub.3                                                                            OCH.sub. 3                                     8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 Cl   OCH.sub.3                                      8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 OCH.sub.3                                                                           Cl                                             8-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             8-OCH.sub.3,1-naphthyl                                                                         H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       8-OCH.sub.3,1-naphthyl                                                                         H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       8-OCH.sub.3,1-naphthyl                                                                         H   H  7/9 Cl   CH.sub.3                                       8-OCH.sub.3,1-naphthyl                                                                         H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       8-OCH.sub.3,1-naphthyl                                                                         H   H  7/9 CH.sub.3                                                                            Cl                                             8-OCH.sub.3,1-naphthyl                                                                         H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             8-OCH.sub.3,1-naphthyl                                                                         H   H  7/9 Cl   Cl                                             8-OCH.sub.3,1-naphthyl                                                                         H   CH.sub.3                                                                          7   Cl   Cl                                             8-OCH.sub.3,1-naphthyl                                                                         H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      8-OCH.sub.3,1-naphthyl                                                                         H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      8-OCH.sub.3,1-naphthyl                                                                         H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      8-OCH.sub.3,1-naphthyl                                                                         H   CH.sub.3                                                                          7   CH.sub. 3                                                                           OCH.sub.3                                      8-OCH.sub.3,1-naphthyl                                                                         H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       8-OCH.sub.3,1-naphthyl                                                                         H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       8-OCH.sub.3,1-naphthyl                                                                         H   H  7/9 Cl   OCH.sub.3                                      8-OCH.sub.3,1-naphthyl                                                                         H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      8-OCH.sub.3,1-naphthyl                                                                         H   H  7/9 OCH.sub.3                                                                           Cl                                             8-OCH.sub.3,1-naphthyl                                                                         H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   H  7/9 Cl   CH.sub.3                                       8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   H  7/9 CH.sub.3                                                                            Cl                                             8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   H  7/9 Cl   Cl                                             8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   CH.sub.3                                                                          7   Cl   Cl                                             8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      8-OCH.sub. 2 CH.sub.2 OCH.sub.3,1-naphthyl                                                     H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   H  7/9 Cl   OCH.sub.3                                      8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   H  7/9 OCH.sub.3                                                                           Cl                                             8-OCH.sub.2 CH.sub.2 OCH.sub.3,1-naphthyl                                                      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   H  7/9 Cl   CH.sub.3                                       8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   H  7/9 CH.sub.3                                                                            Cl                                             8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   H  7/9 Cl   Cl                                             8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   CH.sub.3                                                                          7   Cl   Cl                                             8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   H  7/9 Cl   OCH.sub.3                                      8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   H  7/9 OCH.sub.3                                                                           Cl                                             8-OCH.sub.2 CH.sub.2 Cl,1-naphthyl                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   H  7/9 Cl   CH.sub.3                                       8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   H  7/9 CH.sub.3                                                                            Cl                                             8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   H  7/9 Cl   Cl                                             8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   CH.sub.3                                                                          7   Cl   Cl                                             8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   H  7/9 Cl   OCH.sub.3                                      8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   H  7/9 OCH.sub.3                                                                           Cl                                             8-OCH.sub.2 CO.sub.2 CH.sub.3,1-naphthyl                                                       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-Cl,1-naphthyl H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-Cl,1-naphthyl H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-Cl,1-naphthyl H   H  7/9 Cl   CH.sub.3                                       2-Cl,1-naphthyl H   CH.sub. 3                                                                         7   Cl   CH.sub.3                                       2-Cl,1-naphthyl H   H  7/9 CH.sub.3                                                                            Cl                                             2-Cl,1-naphthyl H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-Cl,1-naphthyl H   H  7/9 Cl   Cl                                             2-Cl,1-naphthyl H   CH.sub.3                                                                          7   Cl   Cl                                             2-Cl,1-naphthyl H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,1-naphthyl H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,1-naphthyl H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-Cl,1-naphthyl H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-Cl,1-naphthyl H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-Cl,1-naphthyl H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-Cl,1-naphthyl H   H  7/9 Cl   OCH.sub.3                                      2-Cl,1-naphthyl H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-Cl,1-naphthyl H   H  7/9 OCH.sub.3                                                                           Cl                                             2-Cl,1-naphthyl H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 Cl   Cl                                             2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   Cl   Cl                                             2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,1-naphthyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-naphthyl      H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-naphthyl      H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-naphthyl      H   H  7/9 Cl   CH.sub.3                                       2-naphthyl      H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-naphthyl      H   H  7/9 CH.sub.3                                                                            Cl                                             2-naphthyl      H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-naphthyl      H   H  7/9 Cl   Cl                                             2-naphthyl      H   CH.sub.3                                                                          7   Cl   Cl                                             2-naphthyl      H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-naphthyl      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-naphthyl      H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-naphthyl      H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-naphthyl      H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-naphthyl      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-naphthyl      H   H  7/9 Cl   OCH.sub.3                                      2-naphthyl      H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-naphthyl      H   H  7/9 OCH.sub.3                                                                           Cl                                             2-naphthyl      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             1-Cl,2-napthyl  H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       1-Cl,2-napthyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       1-Cl,2-napthyl  H   H  7/9 Cl   CH.sub.3                                       1-Cl,2-napthyl  H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       1-Cl,2-napthyl  H   H  7/9 CH.sub.3                                                                            Cl                                             1-Cl,2-napthyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             1-Cl,2-napthyl  H   H  7/9 Cl   Cl                                             1-Cl,2-napthyl  H   CH.sub.3                                                                          7   Cl   Cl                                             1-Cl,2-napthyl  H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      1-Cl,2-napthyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      1-Cl,2-napthyl  H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      1-Cl,2-napthyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      1-Cl,2-napthyl  H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       1-Cl,2-napthyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       1-Cl,2-napthyl  H   H  7/9 Cl   OCH.sub.3                                      1-Cl,2-napthyl  H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      1-Cl,2-napthyl  H   H  7/9 OCH.sub.3                                                                           Cl                                             1-Cl,2-napthyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   H  7/9 Cl   CH.sub.3                                       1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   H  7/9 CH.sub.3                                                                            Cl                                             1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   H  7/9 Cl   Cl                                             1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   CH.sub.3                                                                          7   Cl   Cl                                             1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   H  7/9 Cl   OCH.sub.3                                      1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      1-CO.sub. 2 CH.sub.3,2-napthyl                                                                 H   H  7/9 OCH.sub.3                                                                           Cl                                             1-CO.sub.2 CH.sub.3,2-napthyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   H  7/9 Cl   CH.sub.3                                       1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   H  7/9 CH.sub.3                                                                            Cl                                             1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   H  7/9 Cl   Cl                                             1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   CH.sub.3                                                                          7   Cl   Cl                                             1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   H  7/9 Cl   OCH.sub.3                                      1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   H  7/9 OCH.sub.3                                                                           Cl                                             1-OCH.sub.2 CH.sub.2 OCH.sub.3,2-naphthyl                                                      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   H  7/9 Cl   CH.sub.3                                       1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   H  7/9 CH.sub.3                                                                            Cl                                             1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   H  7/9 Cl   Cl                                             1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   CH.sub.3                                                                          7   Cl   Cl                                             1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   H  7/9 Cl   OCH.sub.3                                      1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   H  7/9 OCH.sub.3                                                                           Cl                                             1-OCH.sub.2 CH.sub.2 Cl,2-naphthyl                                                             H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   H  7/9 Cl   CH.sub.3                                       1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   H  7/9 CH.sub.3                                                                            Cl                                             1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   H  7/9 Cl   Cl                                             1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   CH.sub.3                                                                          7   Cl   Cl                                             1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   H  7/9 Cl   OCH.sub.3                                      1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   H  7/9 OCH.sub.3                                                                           Cl                                             1-OCH.sub.2 CO.sub.2 CH.sub.3,2-naphthyl                                                       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-thienyl       H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-thienyl       H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-thienyl       H   H  7/9 Cl   CH.sub.3                                       2-thienyl       H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-thienyl       H   H  7/9 CH.sub.3                                                                            Cl                                             2-thienyl       H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-thienyl       H   H  7/9 Cl   Cl                                             2-thienyl       H   CH.sub.3                                                                          7   Cl   Cl                                             2-thienyl       H   H  7/9 OCH.sub.3                                                                           OCH.sub. 3                                     2-thienyl       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-thienyl       H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-thienyl       H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-thienyl       H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-thienyl       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-thienyl       H   H  7/9 Cl   OCH.sub.3                                      2-thienyl       H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-thienyl       H   H  7/9 OCH.sub.3                                                                           Cl                                             2-thienyl       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             3-Cl,2-thienyl  H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       3-Cl,2-thienyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       3-Cl,2-thienyl  H   H  7/9 Cl   CH.sub.3                                       3-Cl,2-thienyl  H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       3-Cl,2-thienyl  H   H  7/9 CH.sub.3                                                                            Cl                                             3-Cl,2-thienyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             3-Cl,2-thienyl  H   H  7/9 Cl   Cl                                             3-Cl,2-thienyl  H   CH.sub.3                                                                          7   Cl   Cl                                             3-Cl,2-thienyl  H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      3-Cl,2-thienyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      3-Cl,2-thienyl  H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      3-Cl,2-thienyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      3-Cl,2-thienyl  H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       3-Cl,2-thienyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       3-Cl,2-thienyl  H   H  7/9 Cl   OCH.sub.3                                      3-Cl,2-thienyl  H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      3-Cl,2-thienyl  H   H  7/9 OCH.sub.3                                                                           Cl                                             3-Cl,2-thienyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             3-Cl,2-thienyl  CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            CH.sub.3                                       3-Cl,2-thienyl  CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       3-Cl,2-thienyl  CH.sub.3                                                                           H  7/9 Cl   CH.sub.3                                       3-Cl,2-thienyl  CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   CH.sub.3                                       3-Cl,2-thienyl  CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            Cl                                             3-Cl,2-thienyl  CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             3-Cl,2-thienyl  CH.sub.3                                                                           H  7/9 Cl   Cl                                             3-Cl,2-thienyl  CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   Cl                                             3-Cl,2-thienyl  CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      3-Cl,2-thienyl  CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      3-Cl,2-thienyl  CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            OCH.sub.3                                      3-Cl,2-thienyl  CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      3-Cl,2-thienyl  CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           CH.sub.3                                       3-Cl,2-thienyl  CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       3-Cl,2-thienyl  CH.sub.3                                                                           H  7/9 Cl   OCH.sub.3                                      3-Cl,2-thienyl  CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   OCH.sub.3                                      3-Cl,2-thienyl  CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           Cl                                             3-Cl,2-thienyl  CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             3-Cl,2-thienyl  H   H  7/9 CF.sub.3                                                                            CF.sub.3                                       3-Cl,2-thienyl  H   CH.sub.3                                                                          7   CF.sub.3                                                                            CF.sub.3                                       3-Cl,2-thienyl  H   H  7/9 Cl   CF.sub.3                                       3-Cl,2-thienyl  H   CH.sub.3                                                                          7   Cl   CF.sub.3                                       3-Cl,2-thienyl  H   H  7/9 CF.sub.3                                                                            Cl                                             3-Cl,2-thienyl  H   CH.sub.3                                                                          7   CF.sub.3                                                                            Cl                                             3-Cl,2-thienyl  H   H  7/9 F    CF.sub.3                                       3-Cl,2-thienyl  H   CH.sub.3                                                                          7   F    CF.sub.3                                       3-Cl,2-thienyl  H   H  7/9 CF.sub.3                                                                            F                                              3-Cl,2-thienyl  H   CH.sub.3                                                                          7   CF.sub.3                                                                            F                                              3-Cl,2-thienyl  H   H  7/9 CH.sub.3                                                                            CF.sub.3                                       3-Cl,2-thienyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            CF.sub.3                                       3-Cl,2-thienyl  H   H  7/9 CF.sub.3                                                                            CH.sub.3                                       3-Cl,2-thienyl  H   CH.sub.3                                                                          7   CF.sub.3                                                                            CH.sub.3                                       3-Cl,2-thienyl  H   H  7/9 OCH.sub.3                                                                           CF.sub.3                                       3-Cl,2-thienyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CF.sub.3                                       3-Cl,2-thienyl  H   H  7/9 CF.sub.3                                                                            OCH.sub.3                                      3-Cl,2-thienyl  H   CH.sub.3                                                                          7   CF.sub.3                                                                            OCH.sub.3                                      3-Cl,2-thienyl  H   H  7/9 F    F                                              3-Cl,2-thienyl  H   CH.sub.3                                                                          7   F    F                                              3-Cl,2-thienyl  H   H  7/9 F    Cl                                             3-Cl,2-thienyl  H   CH.sub.3                                                                          7   F    Cl                                             3-Cl,2-thienyl  H   H  7/9 Cl   F                                              3-Cl,2-thienyl  H   CH.sub.3                                                                          7   Cl   F                                              3-Cl,2-thienyl  H   H  7/9 F    CH.sub.3                                       3-Cl,2-thienyl  H   CH.sub.3                                                                          7   F    CH.sub.3                                       3-Cl,2-thienyl  H   H  7/9 CH.sub.3                                                                            F                                              3-Cl,2-thienyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            F                                              3-Cl,2-thienyl  H   H  7/9 F    OCH.sub.3                                      3-Cl,2-thienyl  H   CH.sub.3                                                                          7   F    OCH.sub.3                                      3-Cl,2-thienyl  H   H  7/9 OCH.sub.3                                                                           F                                              3-Cl,2-thienyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           F                                              3-Cl,2-thienyl  H   H  7/9 N(CH.sub.3).sub.2                                                                   Cl                                             3-Cl,2-thienyl  H   CH.sub.3                                                                          7   N(CH.sub.3).sub.2                                                                   Cl                                             3-Cl,2-thienyl  H   H  7/9 SCH.sub.3                                                                           Cl                                             3-Cl,2-thienyl  H   CH.sub.3                                                                          7   SCH.sub.3                                                                           Cl                                             4-Cl,2-thienyl  H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       4-Cl,2-thienyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       4-Cl,2-thienyl  H   H  7/9 Cl   CH.sub.3                                       4-Cl,2-thienyl  H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       4-Cl,2-thienyl  H   H  7/9 CH.sub.3                                                                            Cl                                             4-Cl,2-thienyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             4-Cl,2-thienyl  H   H  7/9 Cl   Cl                                             4-Cl,2-thienyl  H   CH.sub.3                                                                          7   Cl   Cl                                             4-Cl,2-thienyl  H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      4-Cl,2-thienyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      4-Cl,2-thienyl  H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      4-Cl,2-thienyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      4-Cl,2-thienyl  H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       4-Cl,2-thienyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       4-Cl,2-thienyl  H   H  7/9 Cl   OCH.sub.3                                      4-Cl,2-thienyl  H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      4-Cl,2-thienyl  H   H  7/9 OCH.sub.3                                                                           Cl                                             4-Cl,2-thienyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             5-Cl,2-thienyl  H   H  7/9 CH.sub.3                                                                            CH.sub. 3                                      5-Cl,2-thienyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       5-Cl,2-thienyl  H   H  7/9 Cl   CH.sub.3                                       5-Cl,2-thienyl  H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       5-Cl,2-thienyl  H   H  7/9 CH.sub.3                                                                            Cl                                             5-Cl,2-thienyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             5-Cl,2-thienyl  H   H  7/9 Cl   Cl                                             5-Cl,2-thienyl  H   CH.sub.3                                                                          7   Cl   Cl                                             5-Cl,2-thienyl  H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      5-Cl,2-thienyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      5-Cl,2-thienyl  H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      5-Cl,2-thienyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      5-Cl,2-thienyl  H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       5-Cl,2-thienyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       5-Cl,2-thienyl  H   H  7/9 Cl   OCH.sub.3                                      5-Cl,2-thienyl  H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      5-Cl,2-thienyl  H   H  7/9 OCH.sub.3                                                                           Cl                                             5-Cl,2-thienyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   H  7/9 Cl   CH.sub.3                                       3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   H  7/9 CH.sub.3                                                                            Cl                                             3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   CH.sub. 3                                                                         7   CH.sub.3                                                                            Cl                                             3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   H  7/9 Cl   Cl                                             3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   CH.sub.3                                                                          7   Cl   Cl                                             3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   H  7/9 Cl   OCH.sub.3                                      3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   H  7/9 OCH.sub.3                                                                           Cl                                             3-CO.sub.2 CH.sub.3,2-thienyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 Cl   Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   Cl   Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           H  7/9 Cl   CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-CO.sub. 2 CH.sub.3,3-thienyl                                                                 CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           H  7/9 Cl   Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           H  7/9 Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 CF.sub.3                                                                            CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   CF.sub. 3                                                                           CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 Cl   CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   Cl   CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 CF.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   CF.sub.3                                                                            Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 F    CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   F    CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 CF.sub.3                                                                            F                                              2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   CF.sub.3                                                                            F                                              2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 CH.sub.3                                                                            CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 CF.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   CF.sub.3                                                                            CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 OCH.sub.3                                                                           CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CF.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 CF.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   CF.sub.3                                                                            OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 F    F                                              2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   F    F                                              2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 F    Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   F    Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 Cl   F                                              2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   Cl   F                                              2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 F    CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   F    CH.sub.3                                       2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 CH.sub.3                                                                            F                                              2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            F                                              2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 F    OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   F    OCH.sub.3                                      2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 OCH.sub.3                                                                           F                                              2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           F                                              2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 N(CH.sub.3).sub.2                                                                   Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   N(CH.sub.3).sub.2                                                                   Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 SCH.sub.3                                                                           Cl                                             2-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   SCH.sub.3                                                                           Cl                                             2-Cl,5-CH.sub.3,3-thienyl                                                                      H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-Cl,5-CH.sub.3,3-thienyl                                                                      H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-Cl,5-CH.sub.3,3-thienyl                                                                      H   H  7/9 Cl   CH.sub.3                                       2-Cl,5-CH.sub.3,3-thienyl                                                                      H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-Cl,5-CH.sub.3,3-thienyl                                                                      H   H  7/9 CH.sub.3                                                                            Cl                                             2-Cl,5-CH.sub.3,3-thienyl                                                                      H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-Cl,5-CH.sub.3,3-thienyl                                                                      H   H  7/9 Cl   Cl                                             2-Cl,5-CH.sub.3,3-thienyl                                                                      H   CH.sub.3                                                                          7   Cl   Cl                                             2-Cl,5-CH.sub.3,3-thienyl                                                                      H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,5-CH.sub.3,3-thienyl                                                                      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-Cl,5-CH.sub.3,3-thienyl                                                                      H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-Cl,5-CH.sub.3,3-thienyl                                                                      H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-Cl,5-CH.sub.3,3-thienyl                                                                      H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-Cl,5-CH.sub.3,3-thienyl                                                                      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-Cl,5-CH.sub.3,3-thienyl                                                                      H   H  7/9 Cl   OCH.sub.3                                      2-Cl,5-CH.sub.3,3-thienyl                                                                      H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-Cl,5-CH.sub.3,3-thienyl                                                                      H   H  7/9 OCH.sub.3                                                                           Cl                                             2-Cl,5-CH.sub.3,3-thienyl                                                                      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 Cl   CH.sub.3                                       4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 CH.sub.3                                                                            Cl                                             4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 Cl   Cl                                             4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   Cl   Cl                                             4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 Cl   OCH.sub.3                                      4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   H  7/9 OCH.sub.3                                                                           Cl                                             4-CO.sub.2 CH.sub.3,3-thienyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 Cl   CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 CH.sub.3                                                                            Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 Cl   Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   Cl   Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 Cl   OCH.sub.3                                      1-CH.sub.3 ,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 OCH.sub.3                                                                           Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           H  7/9 Cl   CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           H  7/9 Cl   Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            OCH.sub. 3                                     1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           H  7/9 Cl   OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 CF.sub.3                                                                            CF.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   CF.sub.3                                                                            CF.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 Cl   CF.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   Cl   CF.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 CF.sub.3                                                                            Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   CF.sub.3                                                                            Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 F    CF.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   F    CF.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 CF.sub.3                                                                            F                                              1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   CF.sub.3                                                                            F                                              1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 CH.sub.3                                                                            CF.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   CH.sub.3                                                                            CF.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 CF.sub.3                                                                            CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   CF.sub.3                                                                            CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 OCH.sub.3                                                                           CF.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CF.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 CF.sub.3                                                                            OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   CF.sub.3                                                                            OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 F    F                                              1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   F    F                                              1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 F    Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   F    Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 Cl   F                                              1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   Cl   F                                              1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 F    CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   F    CH.sub.3                                       1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 CH.sub.3                                                                            F                                              1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   CH.sub.3                                                                            F                                              1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 F    OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   F    OCH.sub.3                                      1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 OCH.sub.3                                                                           F                                              1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   OCH.sub.3                                                                           F                                              1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 N(CH.sub.3).sub.2                                                                   Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   N(CH.sub.3).sub.2                                                                   Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   H  7/9 SCH.sub.3                                                                           Cl                                             1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                     H   CH.sub.3                                                                          7   SCH.sub.3                                                                           Cl                                             2-pyridyl       H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       2-pyridyl       H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       2-pyridyl       H   H  7/9 Cl   CH.sub.3                                       2-pyridyl       H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       2-pyridyl       H   H  7/9 CH.sub.3                                                                            Cl                                             2-pyridyl       H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             2-pyridyl       H   H  7/9 Cl   Cl                                             2-pyridyl       H   CH.sub.3                                                                          7   Cl   Cl                                             2-pyridyl       H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      2-pyridyl       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      2-pyridyl       H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      2-pyridyl       H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      2-pyridyl       H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       2-pyridyl       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       2-pyridyl       H   H  7/9 Cl   OCH.sub.3                                      2-pyridyl       H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      2-pyridyl       H   H  7/9 OCH.sub.3                                                                           Cl                                             2-pyridyl       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             3-Cl,2-pyridyl  H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       3-Cl,2-pyridyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       3-Cl,2-pyridyl  H   H  7/9 Cl   CH.sub.3                                       3-Cl,2-pyridyl  H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       3-Cl,2-pyridyl  H   H  7/9 CH.sub.3                                                                            Cl                                             3-Cl,2-pyridyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             3-Cl,2-pyridyl  H   H  7/9 Cl   Cl                                             3-Cl,2-pyridyl  H   CH.sub.3                                                                          7   Cl   Cl                                             3-Cl,2-pyridyl  H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      3-Cl,2-pyridyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      3-Cl,2-pyridyl  H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      3-Cl,2-pyridyl  H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      3-Cl,2-pyridyl  H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       3-Cl,2-pyridyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       3-Cl,2-pyridyl  H   H  7/9 Cl   OCH.sub.3                                      3-Cl,2-pyridyl  H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      3-Cl,2-pyridyl  H   H  7/9 OCH.sub.3                                                                           Cl                                             3-Cl,2-pyridyl  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   H  7/9 Cl   CH.sub.3                                       3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   H  7/9 CH.sub.3                                                                            Cl                                             3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   H  7/9 Cl   Cl                                             3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   CH.sub.3                                                                          7   Cl   Cl                                             3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      3-CO.sub. 2 CH.sub.3,2-pyridyl                                                                 H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   H  7/9 Cl   OCH.sub.3                                      3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   H  7/9 OCH.sub.3                                                                           Cl                                             3-CO.sub.2 CH.sub.3,2-pyridyl                                                                  H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 Cl   CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 CH.sub.3                                                                            Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 Cl   Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   Cl   Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      3-CON(CH.sub. 3).sub.2,2-pyridyl                                                               H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 Cl   OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 OCH.sub.3                                                                           Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           H  7/9 Cl   CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           H  7/9 Cl   Cl                                             3-CON(CH.sub.3).sub.2 ,2-pyridyl                                                               CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           H  7/9 CH.sub.3                                                                            OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           H  7/9 Cl   OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           CH.sub.3                                                                          7   Cl   OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           H  7/9 OCH.sub.3                                                                           Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                CH.sub.3                                                                           CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 CF.sub.3                                                                            CF.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   CF.sub.3                                                                            CF.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 Cl   CF.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   Cl   CF.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 CF.sub.3                                                                            Cl                                             3-CON(CH.sub.3 ).sub.2,2-pyridyl                                                               H   CH.sub.3                                                                          7   CF.sub.3                                                                            Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 F    CF.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   F    CF.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 CF.sub.3                                                                            F                                              3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   CF.sub.3                                                                            F                                              3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 CH.sub.3                                                                            CF.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   CH.sub.3                                                                            CF.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 CF.sub.3                                                                            CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   CF.sub.3                                                                            CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 OCH.sub.3                                                                           CF.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CF.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 CF.sub.3                                                                            OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   CF.sub.3                                                                            OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 F    F                                              3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   F    F                                              3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 F    Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   F    Cl                                             3-CON(CH.sub.3 ).sub.2,2-pyridyl                                                               H   H  7/9 Cl   F                                              3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   Cl   F                                              3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 F    CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   F    CH.sub.3                                       3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 CH.sub.3                                                                            F                                              3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   CH.sub.3                                                                            F                                              3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 F    OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   F    OCH.sub.3                                      3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 OCH.sub.3                                                                           F                                              3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   OCH.sub.3                                                                           F                                              3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 N(CH.sub.3).sub.2                                                                   Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   N(CH.sub.3).sub.2                                                                   Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   H  7/9 SCH.sub.3                                                                           Cl                                             3-CON(CH.sub.3).sub.2,2-pyridyl                                                                H   CH.sub.3                                                                          7   SCH.sub.3                                                                           Cl                                             3-pyridyl       H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       3-pyridyl       H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       3-pyridyl       H   H  7/9 Cl   CH.sub.3                                       3-pyridyl       H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       3-pyridyl       H   H  7/9 CH.sub.3                                                                            Cl                                             3-pyridyl       H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             3-pyridyl       H   H  7/9 Cl   Cl                                             3-pyridyl       H   CH.sub.3                                                                          7   Cl   Cl                                             3-pyridyl       H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      3-pyridyl       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      3-pyridyl       H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      3-pyridyl       H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      3-pyridyl       H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       3-pyridyl       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       3-pyridyl       H   H  7/9 Cl   OCH.sub.3                                      3-pyridyl       H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      3-pyridyl       H   H  7/9 OCH.sub.3                                                                           Cl                                             3-pyridyl       H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             8-quinolyl      H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       8-quinolyl      H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       8-quinolyl      H   H  7/9 Cl   CH.sub.3                                       8-quinolyl      H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       8-quinolyl      H   H  7/9 CH.sub.3                                                                            Cl                                             8-quinolyl      H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             8-quinolyl      H   H  7/9 Cl   Cl                                             8-quinolyl      H   CH.sub.3                                                                          7   Cl   Cl                                             8-quinolyl      H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      8-quinolyl      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      8-quinolyl      H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      8-quinolyl      H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      8-quinolyl      H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       8-quinolyl      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       8-quinolyl      H   H  7/9 Cl   OCH.sub.3                                      8-quinolyl      H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      8-quinolyl      H   H  7/9 OCH.sub.3                                                                           Cl                                             8-quinolyl      H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   H  7/9 Cl   CH.sub.3                                       7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   H  7/9 CH.sub.3                                                                            Cl                                             7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   H  7/9 Cl   Cl                                             7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   CH.sub.3                                                                          7   Cl   Cl                                             7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       7-CO.sub.2 CH.sub. 3,8-quinolyl                                                                H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   H  7/9 Cl   OCH.sub.3                                      7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   H  7/9 OCH.sub.3                                                                           Cl                                             7-CO.sub.2 CH.sub.3,8-quinolyl                                                                 H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             7-Cl,8-quinolyl H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       7-Cl,8-quinolyl H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       7-Cl,8-quinolyl H   H  7/9 Cl   CH.sub.3                                       7-Cl,8-quinolyl H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       7-Cl,8-quinolyl H   H  7/9 CH.sub.3                                                                            Cl                                             7-Cl,8-quinolyl H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             7-Cl,8-quinolyl H   H  7/9 Cl   Cl                                             7-Cl,8-quinolyl H   CH.sub.3                                                                          7   Cl   Cl                                             7-Cl,8-quinolyl H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      7-Cl,8-quinolyl H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      7-Cl,8-quinolyl H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      7-Cl,8-quinolyl H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      7-Cl,8-quinolyl H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       7-Cl,8-quinolyl H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       7-Cl,8-quinolyl H   H  7/9 Cl   OCH.sub.3                                      7-Cl,8-quinolyl H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      7-Cl,8-quinolyl H   H  7/9 OCH.sub.3                                                                           Cl                                             7-Cl,8-quinolyl H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             7-Cl,8-quinolyl H   H  7/9 CH.sub.3                                                                            CH.sub.3                                       7-Cl,8-quinolyl H   CH.sub.3                                                                          7   CH.sub.3                                                                            CH.sub.3                                       7-Cl,8-quinolyl H   H  7/9 Cl   CH.sub.3                                       7-Cl,8-quinolyl H   CH.sub.3                                                                          7   Cl   CH.sub.3                                       7-Cl,8-quinolyl H   H  7/9 CH.sub.3                                                                            Cl                                             7-Cl,8-quinolyl H   CH.sub.3                                                                          7   CH.sub.3                                                                            Cl                                             7-Cl,8-quinolyl H   H  7/9 Cl   Cl                                             7-Cl,8-quinolyl H   CH.sub.3                                                                          7   Cl   Cl                                             7-Cl,8-quinolyl H   H  7/9 OCH.sub.3                                                                           OCH.sub.3                                      7-Cl,8-quinolyl H   CH.sub.3                                                                          7   OCH.sub.3                                                                           OCH.sub.3                                      7-Cl,8-quinolyl H   H  7/9 CH.sub.3                                                                            OCH.sub.3                                      7-Cl,8-quinolyl H   CH.sub.3                                                                          7   CH.sub.3                                                                            OCH.sub.3                                      7-Cl,8-quinolyl H   H  7/9 OCH.sub.3                                                                           CH.sub.3                                       7-Cl,8-quinolyl H   CH.sub.3                                                                          7   OCH.sub.3                                                                           CH.sub.3                                       7-Cl,8-quinolyl H   H  7/9 Cl   OCH.sub.3                                      7-Cl,8-quinolyl H   CH.sub.3                                                                          7   Cl   OCH.sub.3                                      7-Cl,8-quinolyl H   H  7/9 OCH.sub.3                                                                           Cl                                             7-Cl,8-quinolyl H   CH.sub.3                                                                          7   OCH.sub.3                                                                           Cl                                             __________________________________________________________________________

                  TABLE II                                                         ______________________________________                                          ##STR15##                     Ib                                              A               R.sup.1                                                                              R.sup.2                                                                               Pos. R.sup.3                                                                               R.sup.4                               ______________________________________                                         phenyl          H     H      7/9  CH.sub.3                                                                              CH.sub.3                              phenyl          H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                              phenyl          H     H      7/9  Cl     CH.sub.3                              phenyl          H     CH.sub.3                                                                              7    Cl     CH.sub.3                              phenyl          H     H      7/9  CH.sub.3                                                                              Cl                                    phenyl          H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl                                    phenyl          H     H      7/9  Cl     Cl                                    phenyl          H     CH.sub.3                                                                              7    Cl     Cl                                    phenyl          H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                             phenyl          H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                             phenyl          H     H      7/9  CH.sub.3                                                                              OCH.sub.3                             phenyl          H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                             phenyl          H     H      7/9  OCH.sub.3                                                                             CH.sub.3                              phenyl          H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                              phenyl          H     H      7/9  Cl     OCH.sub.3                             phenyl          H     CH.sub.3                                                                              7    Cl     OCH.sub.3                             phenyl          H     H      7/9  OCH.sub.3                                                                             Cl                                    phenyl          H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl                                    2-Cl-phenyl     H     H      7/9  CH.sub.3                                                                              CH.sub.3                              2-Cl-phenyl     H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                              2-Cl-phenyl     H     H      7/9  Cl     CH.sub.3                              2-Cl-phenyl     H     CH.sub.3                                                                              7    Cl     CH.sub.3                              2-Cl-phenyl     H     H      7/9  CH.sub.3                                                                              Cl                                    2-Cl-phenyl     H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl                                    2-Cl-phenyl     H     H      7/9  Cl     Cl                                    2-Cl-phenyl     H     CH.sub.3                                                                              7    Cl     Cl                                    2-Cl-phenyl     H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                             2-Cl-phenyl     H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                             2-Cl-phenyl     H     H      7/9  CH.sub.3                                                                              OCH.sub.3                             2-Cl-phenyl     H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                             2-Cl-phenyl     H     H      7/9  OCH.sub.3                                                                             CH.sub.3                              2-Cl-phenyl     H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                              2-Cl-phenyl     H     H      7/9  Cl     OCH.sub.3                             2-Cl-phenyl     H     CH.sub.3                                                                              7    Cl     OCH.sub.3                             2-Cl-phenyl     H     H      7/9  OCH.sub.3                                                                             Cl                                    2-Cl-phenyl     H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl                                    2-F-phenyl      H     H      7/9  CH.sub.3                                                                              CH.sub. 3                             2-F-phenyl      H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                              2-F-phenyl      H     H      7/9  Cl     CH.sub.3                              2-F-phenyl      H     CH.sub.3                                                                              7    Cl     CH.sub.3                              2-F-phenyl      H     H      7/9  CH.sub.3                                                                              Cl                                    2-F-phenyl      H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl                                    2-F-phenyl      H     H      7/9  Cl     Cl                                    2-F-phenyl      H     CH.sub.3                                                                              7    Cl     Cl                                    2-F-phenyl      H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                             2-F-phenyl      H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                             2-F-phenyl      H     H      7/9  CH.sub.3                                                                              OCH.sub.3                             2-F-phenyl      H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                             2-F-phenyl      H     H      7/9  OCH.sub.3                                                                             CH.sub.3                              2-F-phenyl      H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                              2-F-phenyl      H     H      7/9  Cl     OCH.sub.3                             2-F-phenyl      H     CH.sub.3                                                                              7    Cl     OCH.sub.3                             2-F-phenyl      H     H      7/9  OCH.sub.3                                                                             Cl                                    2-F-phenyl      H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl                                    2-CH.sub.3 -phenyl                                                                             H     H      7/9  CH.sub.3                                                                              CH.sub.3                              2-CH.sub.3 -phenyl                                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                              2-CH.sub.3 -phenyl                                                                             H     H      7/9  Cl     CH.sub.3                              2-CH.sub.3 -phenyl                                                                             H     CH.sub.3                                                                              7    Cl     CH.sub.3                              2-CH.sub.3 -phenyl                                                                             H     H      7/9  CH.sub.3                                                                              Cl                                    2-CH.sub.3 -phenyl                                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl                                    2-CH.sub.3 -phenyl                                                                             H     H      7/9  Cl     Cl                                    2-CH.sub.3 -phenyl                                                                             H     CH.sub.3                                                                              7    Cl     Cl                                    2-CH.sub.3 -phenyl                                                                             H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                             2-CH.sub.3 -phenyl                                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                             2-CH.sub.3 -phenyl                                                                             H     H      7/9  CH.sub.3                                                                              OCH.sub.3                             2-CH.sub.3 -phenyl                                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                             2-CH.sub.3 -phenyl                                                                             H     H      7/9  OCH.sub.3                                                                             CH.sub.3                              2-CH.sub.3 -phenyl                                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                              2-CH.sub.3 -phenyl                                                                             H     H      7/9  Cl     OCH.sub.3                             2-CH.sub.3 -phenyl                                                                             H     CH.sub.3                                                                              7    Cl     OCH.sub.3                             2-CH.sub.3 -phenyl                                                                             H     H      7/9  OCH.sub.3                                                                             Cl                                    2-CH.sub.3 -phenyl                                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl                                    2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     H      7/9  CH.sub.3                                                                              CH.sub.3                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     H      7/9  Cl     CH.sub.3                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     CH.sub.3                                                                              7    Cl     CH.sub.3                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     H      7/9  CH.sub.3                                                                              Cl                                    2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl                                    2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     H      7/9  Cl     Cl                                    2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     CH.sub.3                                                                              7    Cl     Cl                                    2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     H      7/9  CH.sub.3                                                                              OCH.sub.3                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     H      7/9  OCH.sub.3                                                                             CH.sub.3                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                              2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     H      7/9  Cl     OCH.sub.3                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     CH.sub.3                                                                              7    Cl     OCH.sub.3                             2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     H      7/9  OCH.sub.3                                                                             Cl                                    2-CO.sub.2 CH.sub.3 -phenyl                                                                    H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl                                    2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     H      7/9  CH.sub.3                                                                              CH.sub.3                              2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                              2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     H      7/9  Cl     CH.sub.3                              2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     CH.sub.3                                                                              7    Cl     CH.sub. 3                             2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     H      7/9  CH.sub.3                                                                              Cl                                    2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl                                    2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     H      7/9  Cl     Cl                                    2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     CH.sub.3                                                                              7    Cl     Cl                                    2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                             2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                             2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     H      7/9  CH.sub.3                                                                              OCH.sub.3                             2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                             2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     H      7/9  OCH.sub.3                                                                             CH.sub.3                              2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                              2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     H      7/9  Cl     OCH.sub.3                             2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     CH.sub.3                                                                              7    Cl     OCH.sub.3                             2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     H      7/9  OCH.sub.3                                                                             Cl                                    2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl                                    2-OCH.sub.3 -phenyl                                                                            H     H      7/9  CH.sub.3                                                                              CH.sub.3                              2-OCH.sub.3 -phenyl                                                                            H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                              2-OCH.sub.3 -phenyl                                                                            H     H      7/9  Cl     CH.sub.3                              2-OCH.sub.3 -phenyl                                                                            H     CH.sub.3                                                                              7    Cl     CH.sub.3                              2-OCH.sub.3 -phenyl                                                                            H     H      7/9  CH.sub.3                                                                              Cl                                    2-OCH.sub.3 -phenyl                                                                            H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl                                    2-OCH.sub.3 -phenyl                                                                            H     H      7/9  Cl     Cl                                    2-OCH.sub.3 -phenyl                                                                            H     CH.sub.3                                                                              7    Cl     Cl                                    2-OCH.sub.3 -phenyl                                                                            H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                             2-OCH.sub.3 -phenyl                                                                            H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                             2-OCH.sub.3 -phenyl                                                                            H     H      7/9  CH.sub.3                                                                              OCH.sub.3                             2-OCH.sub.3 -phenyl                                                                            H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                             2-OCH.sub.3 -phenyl                                                                            H     H      7/9  OCH.sub.3                                                                             CH.sub.3                              2-OCH.sub.3 -phenyl                                                                            H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                              2-OCH.sub.3 -phenyl                                                                            H     H      7/9  Cl     OCH.sub.3                             2-OCH.sub.3 -phenyl                                                                            H     CH.sub.3                                                                              7    Cl     OCH.sub.3                             2-OCH.sub.3 -phenyl                                                                            H     H      7/9  OCH.sub.3                                                                             Cl                                    2-OCH.sub.3 -phenyl                                                                            H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl                                    2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     H      7/9  CH.sub.3                                                                              CH.sub.3                              2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                              2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     H      7/9  Cl     CH.sub.3                              2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     CH.sub.3                                                                              7    Cl     CH.sub.3                              2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     H      7/9  CH.sub.3                                                                              Cl                                    2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl                                    2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     H      7/9  Cl     Cl                                    2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     CH.sub.3                                                                              7    Cl     Cl                                    2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                             2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                             2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     H      7/9  CH.sub.3                                                                              OCH.sub.3                             2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                             2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     H      7/9  OCH.sub.3                                                                             CH.sub.3                              2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                              2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     H      7/9  Cl     OCH.sub.3                             2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     CH.sub.3                                                                              7    Cl     OCH.sub.3                             2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     H      7/9  OCH.sub.3                                                                             Cl                                    2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                         H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl                                    2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     H      7/9  CH.sub.3                                                                              CH.sub.3                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     H      7/9  Cl     CH.sub.3                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     CH.sub.3                                                                              7    Cl     CH.sub.3                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     H      7/9  CH.sub.3                                                                              Cl                                    2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl                                    2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     H      7/9  Cl     Cl                                    2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     CH.sub.3                                                                              7    Cl     Cl                                    2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     H      7/9  CH.sub.3                                                                              OCH.sub.3                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     H      7/9  OCH.sub.3                                                                             CH.sub.3                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                              2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     H      7/9  Cl     OCH.sub.3                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     CH.sub.3                                                                              7    Cl     OCH.sub.3                             2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     H      7/9  OCH.sub.3                                                                             Cl                                    2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                 H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl                                    2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     H      7/9  CH.sub.3                                                                              CH.sub.3                              2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                              2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     H      7/9  Cl     CH.sub.3                              2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     CH.sub.3                                                                              7    Cl     CH.sub.3                              2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     H      7/9  CH.sub.3                                                                              Cl                                    2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl                                    2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     H      7/9  Cl     Cl                                    2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     CH.sub.3                                                                              7    Cl     Cl                                    2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                             2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                             2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     H      7/9  CH.sub.3                                                                              OCH.sub.3                             2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                             2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     H      7/9  OCH.sub.3                                                                             CH.sub.3                              2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                              2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     H      7/9  Cl     OCH.sub.3                             2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     CH.sub.3                                                                              7    Cl     OCH.sub.3                             2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     H      7/9  OCH.sub.3                                                                             Cl                                    2-OCH.sub.2 SO.sub.2 CH.sub.3 -phenyl                                                          H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl                                    2,6-Cl,Cl-phenyl                                                                               H     H      7/9  CH.sub.3                                                                              CH.sub.3                              2,6-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                              2,6-Cl,Cl-phenyl                                                                               H     H      7/9  Cl     CH.sub.3                              2,6-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    Cl     CH.sub.3                              2,6-Cl,Cl-phenyl                                                                               H     H      7/9  CH.sub.3                                                                              Cl                                    2,6-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl                                    2,6-Cl,Cl-phenyl                                                                               H     H      7/9  Cl     Cl                                    2,6-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    Cl     Cl                                    2,6-Cl,Cl-phenyl                                                                               H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                             2,6-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub. 3                            2,6-Cl,Cl-phenyl                                                                               H     H      7/9  CH.sub.3                                                                              OCH.sub.3                             2,6-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                             2,6-Cl,Cl-phenyl                                                                               H     H      7/9  OCH.sub.3                                                                             CH.sub.3                              2,6-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                              2,6-Cl,Cl-phenyl                                                                               H     H      7/9  Cl     OCH.sub.3                             2,6-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    Cl     OCH.sub.3                             2,6-Cl,Cl-phenyl                                                                               H     H      7/9  OCH.sub.3                                                                             Cl                                    2,6-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl                                    2-Cl,6-CH.sub.3 -phenyl                                                                        H     H      7/9  CH.sub.3                                                                              CH.sub.3                              2-Cl,6-CH.sub.3 -phenyl                                                                        H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                              2-Cl,6-CH.sub.3 -phenyl                                                                        H     H      7/9  Cl     CH.sub.3                              2-Cl,6-CH.sub.3 -phenyl                                                                        H     CH.sub.3                                                                              7    Cl     CH.sub.3                              2-Cl,6-CH.sub.3 -phenyl                                                                        H     H      7/9  CH.sub.3                                                                              Cl                                    2-Cl,6-CH.sub.3 -phenyl                                                                        H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl                                    2-Cl,6-CH.sub.3 -phenyl                                                                        H     H      7/9  Cl     Cl                                    2-Cl,6-CH.sub.3 -phenyl                                                                        H     CH.sub.3                                                                              7    Cl     Cl                                    2-Cl,6-CH.sub.3 -phenyl                                                                        H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                             2-Cl,6-CH.sub.3 -phenyl                                                                        H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                             2-Cl,6-CH.sub.3 -phenyl                                                                        H     H      7/9  CH.sub.3                                                                              OCH.sub.3                             2-Cl,6-CH.sub.3 -phenyl                                                                        H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                             2-Cl,6-CH.sub.3 -phenyl                                                                        H     H      7/9  OCH.sub.3                                                                             CH.sub.3                              2-Cl,6-CH.sub.3 -phenyl                                                                        H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                              2-Cl,6-CH.sub.3 -phenyl                                                                        H     H      7/9  Cl     OCH.sub.3                             2-Cl,6-CH.sub.3 -phenyl                                                                        H     CH.sub.3                                                                              7    Cl     OCH.sub.3                             2-Cl,6-CH.sub.3 -phenyl                                                                        H     H      7/9  OCH.sub.3                                                                             Cl                                    2-Cl,6-CH.sub.3 -phenyl                                                                        H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl                                    2,5-Cl,Cl-phenyl                                                                               H     H      7/9  CH.sub.3                                                                              CH.sub.3                              2,5-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                              2,5-Cl,Cl-phenyl                                                                               H     H      7/9  Cl     CH.sub.3                              2,5-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    Cl     CH.sub.3                              2,5-Cl,Cl-phenyl                                                                               H     H      7/9  CH.sub.3                                                                              Cl                                    2,5-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl                                    2,5-Cl,Cl-phenyl                                                                               H     H      7/9  Cl     Cl                                    2,5-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    Cl     Cl                                    2,5-Cl,Cl-phenyl                                                                               H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                             2,5-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                             2,5-Cl,Cl-phenyl                                                                               H     H      7/9  CH.sub.3                                                                              OCH.sub.3                             2,5-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                             2,5-Cl,Cl-phenyl                                                                               H     H      7/9  OCH.sub.3                                                                             CH.sub.3                              2,5-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                              2,5-Cl,Cl-phenyl                                                                               H     H      7/9  Cl     OCH.sub.3                             2,5-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    Cl     OCH.sub.3                             2,5-Cl,Cl-phenyl                                                                               H     H      7/9  OCH.sub.3                                                                             Cl                                    2,5-Cl,Cl-phenyl                                                                               H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl                                    ______________________________________                                    

                                      TABLE III                                    __________________________________________________________________________      ##STR16##                         Ic                                          A              R.sup.1                                                                           R.sup.2                                                                            Pos.                                                                              R.sup.3                                                                              R.sup.4                                                                            R.sup.5                                     __________________________________________________________________________     phenyl         H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           phenyl         H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           phenyl         H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           phenyl         H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           phenyl         H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           phenyl         H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           phenyl         H  H   7/9                                                                               Cl    Cl  H                                           phenyl         H  CH.sub.3                                                                           7  Cl    Cl  H                                           phenyl         H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           phenyl         H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           phenyl         H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           phenyl         H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           phenyl         H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           phenyl         H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           phenyl         H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           phenyl         H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           phenyl         H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           phenyl         H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-Cl-phenyl    H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-Cl-phenyl    H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-Cl-phenyl    H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-Cl-phenyl    H  H   7/9                                                                               Cl    Cl  H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-Cl-phenyl    H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-Cl-phenyl    H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-Cl-phenyl    H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-Cl-phenyl    H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-Cl-phenyl    H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-Cl-phenyl    H  H   7/9                                                                               CF.sub.3                                                                             CF.sub.3                                                                           H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  CF.sub.3                                                                             CF.sub.3                                                                           H                                           2-Cl-phenyl    H  H   7/9                                                                               Cl    CF.sub.3                                                                           H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  Cl    CF.sub.3                                                                           H                                           2-Cl-phenyl    H  H   7/9                                                                               CF.sub.3                                                                             Cl  H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  CF.sub.3                                                                             Cl  H                                           2-Cl-phenyl    H  H   7/9                                                                               F     CF.sub.3                                                                           H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  F     CF.sub.3                                                                           H                                           2-Cl-phenyl    H  H   7/9                                                                               CF.sub.3                                                                             F   H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  CF.sub.3                                                                             F   H                                           2-Cl-phenyl    H  H   7/9                                                                               CH.sub.3                                                                             CF.sub.3                                                                           H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  CH.sub.3                                                                             CF.sub.3                                                                           H                                           2-Cl-phenyl    H  H   7/9                                                                               CF.sub.3                                                                             CH.sub.3                                                                           H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  CF.sub.3                                                                             CH.sub.3                                                                           H                                           2-Cl-phenyl    H  H   7/9                                                                               OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2-Cl-phenyl    H  H   7/9                                                                               CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2-Cl-phenyl    H  H   7/9                                                                               F     F   H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  F     F   H                                           2-Cl-phenyl    H  H   7/9                                                                               F     Cl  H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  F     Cl  H                                           2-Cl-phenyl    H  H   7/9                                                                               Cl    F   H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  Cl    F   H                                           2-Cl-phenyl    H  H   7/9                                                                               F     CH.sub.3                                                                           H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  F     CH.sub.3                                                                           H                                           2-Cl-phenyl    H  H   7/9                                                                               CH.sub.3                                                                             F   H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  CH.sub.3                                                                             F   H                                           2-Cl-phenyl    H  H   7/9                                                                               F     OCH.sub.3                                                                          H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  F     OCH.sub.3                                                                          H                                           2-Cl-phenyl    H  H   7/9                                                                               OCH.sub.3                                                                            F   H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  OCH.sub.3                                                                            F   H                                           2-Cl-phenyl    H  H   7/9                                                                               N(CH.sub.3).sub.2                                                                    Cl  H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  N(CH.sub.3).sub.2                                                                    Cl  H                                           2-Cl-phenyl    H  H   7/9                                                                               SCH.sub.3                                                                            Cl  H                                           2-Cl-phenyl    H  CH.sub.3                                                                           7  SCH.sub.3                                                                            Cl  H                                           2-F-phenyl     H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-F-phenyl     H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-F-phenyl     H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-F-phenyl     H  CH.sub. 3                                                                          7  Cl    CH.sub.3                                                                           H                                           2-F-phenyl     H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-F-phenyl     H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-F-phenyl     H  H   7/9                                                                               Cl    Cl  H                                           2-F-phenyl     H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-F-phenyl     H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-F-phenyl     H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-F-phenyl     H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-F-phenyl     H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-F-phenyl     H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-F-phenyl     H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-F-phenyl     H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-F-phenyl     H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-F-phenyl     H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-F-phenyl     H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-CN-phenyl    H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CN-phenyl    H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CN-phenyl    H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-CN-phenyl    H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-CN-phenyl    H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-CN-phenyl    H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-CN-phenyl    H  H   7/9                                                                               Cl    Cl  H                                           2-CN-phenyl    H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-CN-phenyl    H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CN-phenyl    H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CN-phenyl    H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CN-phenyl    H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CN-phenyl    H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CN-phenyl    H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CN-phenyl    H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-CN-phenyl    H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-CN-phenyl    H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-CN-phenyl    H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-CF.sub.3 -phenyl                                                                            H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CF.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CF.sub.3 -phenyl                                                                            H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-CF.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-CF.sub.3 -phenyl                                                                            H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-CF.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-CF.sub.3 -phenyl                                                                            H  H   7/9                                                                               Cl    Cl  H                                           2-CF.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-CF.sub. 3 -phenyl                                                                           H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CF.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CF.sub.3 -phenyl                                                                            H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CF.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CF.sub.3 -phenyl                                                                            H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CF.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CF.sub.3 -phenyl                                                                            H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-CF.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-CF.sub.3 -phenyl                                                                            H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-CF.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-NO.sub.2 -phenyl                                                                            H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-NO.sub.2 -phenyl                                                                            H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-NO.sub.2 -phenyl                                                                            H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-NO.sub.2 -phenyl                                                                            H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-NO.sub.2 -phenyl                                                                            H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-NO.sub.2 -phenyl                                                                            H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-NO.sub.2 -phenyl                                                                            H  H   7/9                                                                               Cl    Cl  H                                           2-NO.sub.2 -phenyl                                                                            H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-NO.sub.2 -phenyl                                                                            H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-NO.sub.2 -phenyl                                                                            H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-NO.sub.2 -phenyl                                                                            H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-NO.sub.2 -phenyl                                                                            H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-NO.sub.2 -phenyl                                                                            H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-NO.sub.2 -phenyl                                                                            H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-NO.sub.2 -phenyl                                                                            H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-NO.sub.2 -phenyl                                                                            H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-NO.sub.2 -phenyl                                                                            H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-NO.sub.2 -phenyl                                                                            H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-CH.sub.3 -phenyl                                                                            H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CH.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CH.sub.3 -phenyl                                                                            H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-CH.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-CH.sub.3 -phenyl                                                                            H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-CH.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-CH.sub.3 -phenyl                                                                            H  H   7/9                                                                               Cl    Cl  H                                           2-CH.sub.3 -phenyl                                                                            H  CH.sub. 3                                                                          7  Cl    Cl  H                                           2-CH.sub.3 -phenyl                                                                            H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CH.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CH.sub.3 -phenyl                                                                            H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CH.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CH.sub.3 -phenyl                                                                            H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CH.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CH.sub.3 -phenyl                                                                            H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-CH.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-CH.sub.3 -phenyl                                                                            H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-CH.sub.3 -phenyl                                                                            H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-CO.sub. 2 CH.sub.3 -phenyl                                                                  H  H   7/9                                                                               Cl    Cl  H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               CF.sub.3                                                                             CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  CF.sub.3                                                                             CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               Cl    CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub. 3 -phenyl                                                                  H  CH.sub.3                                                                           7  Cl    CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               CF.sub.3                                                                             Cl  H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  CF.sub.3                                                                             Cl  H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               F     CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  F     CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               CF.sub.3                                                                             F   H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  CF.sub.3                                                                             F   H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               CH.sub.3                                                                             CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  CH.sub.3                                                                             CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               CF.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  CF.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               F     F   H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  F     F   H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               F     Cl  H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  F     Cl  H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               Cl    F   H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  Cl    F   H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               F     CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  F     CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               CH.sub.3                                                                             F   H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  CH.sub.3                                                                             F   H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               F     OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  F     OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               OCH.sub.3                                                                            F   H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  OCH.sub.3                                                                            F   H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               N(CH.sub.3).sub.2                                                                    Cl  H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  N(CH.sub.3).sub.2                                                                    Cl  H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               SCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  SCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  H   7/9                                                                               Cl    Cl  H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                            H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-COCH.sub.3 -phenyl                                                                          H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-COCH.sub.3 -phenyl                                                                          H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-COCH.sub.3 -phenyl                                                                          H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-COCH.sub.3 -phenyl                                                                          H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-COCH.sub.3 -phenyl                                                                          H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-COCH.sub.3 -phenyl                                                                          H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-COCH.sub.3 -phenyl                                                                          H  H   7/9                                                                               Cl    Cl  H                                           2-COCH.sub.3 -phenyl                                                                          H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-COCH.sub.3 -phenyl                                                                          H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-COCH.sub.3 -phenyl                                                                          H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-COCH.sub.3 -phenyl                                                                          H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-COCH.sub.3 -phenyl                                                                          H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-COCH.sub.3 -phenyl                                                                          H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-COCH.sub.3 -phenyl                                                                          H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-COCH.sub.3 -phenyl                                                                          H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-COCH.sub.3 -phenyl                                                                          H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-COCH.sub.3 -phenyl                                                                          H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-COCH.sub.3 -phenyl                                                                          H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-OCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-OCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-OCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-OCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-OCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-OCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-OCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               Cl    Cl  H                                           2-OCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-OCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-OCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-OCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-OCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-OCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-OCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-OCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-OCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-OCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-OCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  H   7/9                                                                               Cl    Cl  H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-OCH.sub.2 CH.sub.2 OCH.sub.3 -phenyl                                                        H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-OCH.sub.2 CO.sub. 2 CH.sub.3 -phenyl                                                        H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  H   7/9                                                                               Cl    Cl  H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                         H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               Cl    Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub. 3                                                                         H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               CF.sub.3                                                                             CF.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  CF.sub.3                                                                             CF.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               Cl    CF.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  Cl    CF.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               CF.sub.3                                                                             Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  CF.sub.3                                                                             Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               F     CF.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  F     CF.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               CF.sub.3                                                                             F   H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  CF.sub.3                                                                             F   H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               CH.sub.3                                                                             CF.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  CH.sub.3                                                                             CF.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               CF.sub.3                                                                             CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  CF.sub.3                                                                             CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               F     F   H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  F     F   H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               F     Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  F     Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               Cl    F   H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  Cl    F   H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               F     CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  F     CH.sub.3                                                                           H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               CH.sub.3                                                                             F   H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  CH.sub.3                                                                             F   H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               F     OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  F     OCH.sub.3                                                                          H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               OCH.sub.3                                                                            F   H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  OCH.sub.3                                                                            F   H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               N(CH.sub.3).sub.2                                                                    Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  N(CH.sub.3).sub.2                                                                    Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  H   7/9                                                                               SCH.sub.3                                                                            Cl  H                                           2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                                H  CH.sub.3                                                                           7  SCH.sub.3                                                                            Cl  H                                           2-SCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-SCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-SCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-SCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-SCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-SCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-SCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               Cl    Cl  H                                           2-SCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-SCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-SCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-SCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-SCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-SCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-SCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-SCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-SCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-SCH.sub.3 -phenyl                                                                           H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-SCH.sub.3 -phenyl                                                                           H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub. 3                                                                          H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               Cl    Cl  H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-SO.sub.2 CH.sub.3 -phenyl                                                                   H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-SO.sub. 2 CH.sub.3 -phenyl                                                                  H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  H   7/9                                                                               Cl    Cl  H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-SO.sub.2 N(CH.sub. 3).sub.2 -phenyl                                                         H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-SO.sub.2 N(CH.sub.3).sub.2 -phenyl                                                          H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               Cl    Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  Cl    Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CF.sub.3                                                                             CF.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CF.sub.3                                                                             CF.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               Cl    CF.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  Cl    CF.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CF.sub.3                                                                             Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CF.sub.3                                                                             Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               F     CF.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  F     CF.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CF.sub.3                                                                             F   H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CF.sub.3                                                                             F   H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CH.sub.3                                                                             CF.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CH.sub.3                                                                             CF.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CF.sub.3                                                                             CH.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CF.sub.3                                                                             CH.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               F     F   H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  F     F   H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               F     Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  F     Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               Cl    F   H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  Cl    F   H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               F     CH.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  F     CH.sub.3                                                                           H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CH.sub.3                                                                             F   H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CH.sub.3                                                                             F   H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               F     OCH.sub.3                                                                          H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  F     OCH.sub.3                                                                          H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               OCH.sub.3                                                                            F   H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  OCH.sub.3                                                                            F   H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               N(CH.sub.3).sub.2                                                                    Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  N(CH.sub.3).sub.2                                                                    Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               SCH.sub.3                                                                            Cl  H                                           2,6-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  SCH.sub.3                                                                            Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               Cl    Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               CF.sub.3                                                                             CF.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  CF.sub.3                                                                             CF.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               Cl    CF.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  Cl    CF.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               CF.sub.3                                                                             Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  CF.sub.3                                                                             Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               F     CF.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  F     CF.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               CF.sub.3                                                                             F   H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  CF.sub.3                                                                             F   H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               CH.sub.3                                                                             CF.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  CH.sub.3                                                                             CF.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               CF.sub.3                                                                             CH.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  CF.sub.3                                                                             CH.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               F     F   H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  F     F   H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               F     Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  F     Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               Cl    F   H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  Cl    F   H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               F     CH.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  F     CH.sub.3                                                                           H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               CH.sub.3                                                                             F   H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  CH.sub.3                                                                             F   H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               F     OCH.sub.3                                                                          H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  F     OCH.sub.3                                                                          H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               OCH.sub.3                                                                            F   H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  OCH.sub.3                                                                            F   H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               N(CH.sub.3).sub.2                                                                    Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  N(CH.sub.3).sub.2                                                                    Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  H   7/9                                                                               SCH.sub.3                                                                            Cl  H                                           2-Cl,6-CH.sub.3 -phenyl                                                                       H  CH.sub.3                                                                           7  SCH.sub.3                                                                            Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               Cl    Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  Cl    Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CF.sub.3                                                                             CF.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CF.sub.3                                                                             CF.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               Cl    CF.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  Cl    CF.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CF.sub.3                                                                             Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CF.sub.3                                                                             Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               F     CF.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  F     CF.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CF.sub.3                                                                             F   H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CF.sub.3                                                                             F   H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CH.sub.3                                                                             CF.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CH.sub.3                                                                             CF.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CF.sub.3                                                                             CH.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CF.sub.3                                                                             CH.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               F     F   H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  F     F   H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               F     Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  F     Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               Cl    F   H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  Cl    F   H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               F     CH.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  F     CH.sub.3                                                                           H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               CH.sub.3                                                                             F   H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  CH.sub.3                                                                             F   H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               F     OCH.sub.3                                                                          H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  F     OCH.sub.3                                                                          H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               OCH.sub.3                                                                            F   H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  OCH.sub.3                                                                            F   H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               N(CH.sub.3).sub.2                                                                    Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  N(CH.sub.3).sub.2                                                                    Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  H   7/9                                                                               SCH.sub.3                                                                            Cl  H                                           2,5-Cl,Cl-phenyl                                                                              H  CH.sub.3                                                                           7  SCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               Cl    Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               F     F   H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  F     F   H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               F     Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  F     Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               Cl    F   H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  Cl    F   H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               F     CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  F     CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               CH.sub.3                                                                             F   H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  CH.sub.3                                                                             F   H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               F     OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  F     OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               OCH.sub.3                                                                            F   H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  OCH.sub.3                                                                            F   H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               N(CH.sub.3).sub.2                                                                    Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  N(CH.sub.3).sub.2                                                                    Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               SCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  SCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               CF.sub.3                                                                             CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  CF.sub.3                                                                             CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               Cl    CF.sub.3                                                                           H                                           2-CO.sub. 2 CH.sub.3,3-F-phenyl                                                               H  CH.sub.3                                                                           7  Cl    CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               CF.sub.3                                                                             Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  CF.sub.3                                                                             Cl  H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               F     CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  F     CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               CF.sub.3                                                                             F   H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  CF.sub.3                                                                             F   H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               CH.sub.3                                                                             CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  CH.sub.3                                                                             CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               CF.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  CF.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  H   7/9                                                                               CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-F-phenyl                                                                H  CH.sub.3                                                                           7  CF.sub.3                                                                             OCH.sub.3                                                                          H                                           3-Cl-thienyl   H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           3-Cl-thienyl   H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           3-Cl-thienyl   H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           3-Cl-thienyl   H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           3-Cl-thienyl   H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           3-Cl-thienyl   H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           3-Cl-thienyl   H  H   7/9                                                                               Cl    Cl  H                                           3-Cl-thienyl   H  CH.sub.3                                                                           7  Cl    Cl  H                                           3-Cl-thienyl   H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           3-Cl-thienyl   H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           3-Cl-thienyl   H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           3-Cl-thienyl   H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           3-Cl-thienyl   H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           3-Cl-thienyl   H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           3-Cl-thienyl   H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           3-Cl-thienyl   H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           3-Cl-thienyl   H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           3-Cl-thienyl   H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               Cl    Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  Cl    Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub. 3                                                                          7  OCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               CF.sub.3                                                                             CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  CF.sub.3                                                                             CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               Cl    CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  Cl    CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               CF.sub.3                                                                             Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  CF.sub.3                                                                             Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               F     CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  F     CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               CF.sub.3                                                                             F   H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  CF.sub.3                                                                             F   H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               CH.sub.3                                                                             CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  CH.sub.3                                                                             CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               CF.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  CF.sub.3                                                                             CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CF.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  CF.sub.3                                                                             OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               F     F   H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  F     F   H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               F     Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  F     Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               Cl    F   H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  Cl    F   H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               F     CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  F     CH.sub.3                                                                           H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               CH.sub.3                                                                             F   H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  CH.sub.3                                                                             F   H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               F     OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  F     OCH.sub.3                                                                          H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               OCH.sub.3                                                                            F   H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  OCH.sub.3                                                                            F   H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               N(CH.sub.3).sub.2                                                                    Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  N(CH.sub.3).sub.2                                                                    Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  H   7/9                                                                               SCH.sub.3                                                                            Cl  H                                           2-CO.sub.2 CH.sub.3,3-thienyl                                                                 H  CH.sub.3                                                                           7  SCH.sub.3                                                                            Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               Cl    Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  Cl    Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               CF.sub.3                                                                             CF.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  CF.sub.3                                                                             CF.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               Cl    CF.sub. 3                                                                          H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  Cl    CF.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               CF.sub.3                                                                             Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  CF.sub.3                                                                             Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               F     CF.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  F     CF.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               CF.sub.3                                                                             F   H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  CF.sub.3                                                                             F   H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               CH.sub.3                                                                             CF.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  CH.sub.3                                                                             CF.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               CF.sub.3                                                                             CH.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  CF.sub.3                                                                             CH.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               OCH.sub.3                                                                            CF.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  OCH.sub. 3                                                                           CF.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               CF.sub.3                                                                             OCH.sub.3                                                                          H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  CF.sub.3                                                                             OCH.sub.3                                                                          H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               F     F   H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  F     F   H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               F     Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  F     Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               Cl    F   H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  Cl    F   H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               F     CH.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  F     CH.sub.3                                                                           H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               CH.sub.3                                                                             F   H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  CH.sub.3                                                                             F   H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               F     OCH.sub.3                                                                          H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3 ,5-pyrazolyl                                                   H  CH.sub.3                                                                           7  F     OCH.sub.3                                                                          H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               OCH.sub.3                                                                            F   H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  OCH.sub.3                                                                            F   H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               N(CH.sub.3).sub.2                                                                    Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  N(CH.sub.3).sub.2                                                                    Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  H   7/9                                                                               SCH.sub.3                                                                            Cl  H                                           1-CH.sub.3,4-CO.sub.2 CH.sub.3,5-pyrazolyl                                                    H  CH.sub.3                                                                           7  SCH.sub.3                                                                            Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               CH.sub.3                                                                             CH.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  CH.sub.3                                                                             CH.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               Cl    CH.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  Cl    CH.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               CH.sub.3                                                                             Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  CH.sub.3                                                                             Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               Cl    Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  Cl    Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  OCH.sub.3                                                                            OCH.sub.3                                                                          H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               CH.sub.3                                                                             OCH.sub.3                                                                          H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  CH.sub.3                                                                             OCH.sub.3                                                                          H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               OCH.sub.3                                                                            CH.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CH.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               Cl    OCH.sub.3                                                                          H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  Cl    OCH.sub.3                                                                          H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               OCH.sub.3                                                                            Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  OCH.sub.3                                                                            Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               CF.sub.3                                                                             CF.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  CF.sub.3                                                                             CF.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               Cl    CF.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  Cl    CF.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               CF.sub.3                                                                             Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  CF.sub.3                                                                             Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               F     CF.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  F     CF.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               CF.sub.3                                                                             F   H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  CF.sub.3                                                                             F   H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               CH.sub.3                                                                             CF.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  CH.sub.3                                                                             CF.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               CF.sub.3                                                                             CH.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  CF.sub.3                                                                             CH.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               OCH.sub.3                                                                            CF.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  OCH.sub.3                                                                            CF.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               CF.sub.3                                                                             OCH.sub.3                                                                          H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  CF.sub.3                                                                             OCH.sub.3                                                                          H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               F     F   H                                           3-CON(CH.sub.3).sub.2 ,2-pyridyl                                                              H  CH.sub.3                                                                           7  F     F   H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               F     Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  F     Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               Cl    F   H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  Cl    F   H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               F     CH.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  F     CH.sub.3                                                                           H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               CH.sub.3                                                                             F   H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  CH.sub.3                                                                             F   H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               F     OCH.sub.3                                                                          H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  F     OCH.sub.3                                                                          H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               OCH.sub.3                                                                            F   H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  OCH.sub.3                                                                            F   H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               N(CH.sub.3).sub.2                                                                    Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  N(CH.sub.3).sub.2                                                                    Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  H   7/9                                                                               SCH.sub.3                                                                            Cl  H                                           3-CON(CH.sub.3).sub.2,2-pyridyl                                                               H  CH.sub.3                                                                           7  SCH.sub.3                                                                            Cl  H                                           __________________________________________________________________________

                  TABLE IV                                                         ______________________________________                                          ##STR17##                     Id                                              A             R.sup.1                                                                              R.sup.2                                                                               Pos. R.sup.3                                                                               R.sup.4                                                                              R.sup.5                           ______________________________________                                         phenyl        H     H      7/9  CH.sub.3                                                                              CH.sub.3                                                                             H                                 phenyl        H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                                                                             H                                 phenyl        H     H      7/9  Cl     CH.sub.3                                                                             H                                 phenyl        H     CH.sub.3                                                                              7    Cl     CH.sub.3                                                                             H                                 phenyl        H     H      7/9  CH.sub.3                                                                              Cl    H                                 phenyl        H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl    H                                 phenyl        H     H      7/9  Cl     Cl    H                                 phenyl        H     CH.sub.3                                                                              7    Cl     Cl    H                                 phenyl        H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 phenyl        H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 phenyl        H     H      7/9  CH.sub.3                                                                              OCH.sub.3                                                                            H                                 phenyl        H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                                                                            H                                 phenyl        H     H      7/9  OCH.sub.3                                                                             CH.sub.3                                                                             H                                 phenyl        H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                                                                             H                                 phenyl        H     H      7/9  Cl     OCH.sub.3                                                                            H                                 phenyl        H     CH.sub.3                                                                              7    Cl     OCH.sub.3                                                                            H                                 phenyl        H     H      7/9  OCH.sub.3                                                                             Cl    H                                 phenyl        H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl    H                                 2-Cl-phenyl   H     H      7/9  CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-Cl-phenyl   H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-Cl-phenyl   H     H      7/9  Cl     CH.sub.3                                                                             H                                 2-Cl-phenyl   H     CH.sub.3                                                                              7    Cl     CH.sub.3                                                                             H                                 2-Cl-phenyl   H     H      7/9  CH.sub.3                                                                              Cl    H                                 2-Cl-phenyl   H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl    H                                 2-Cl-phenyl   H     H      7/9  Cl     Cl    H                                 2-Cl-phenyl   H     CH.sub.3                                                                              7    Cl     Cl    H                                 2-Cl-phenyl   H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-Cl-phenyl   H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-Cl-phenyl   H     H      7/9  CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-Cl-phenyl   H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-Cl-phenyl   H     H      7/9  OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-Cl-phenyl   H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-Cl-phenyl   H     H      7/9  Cl     OCH.sub.3                                                                            H                                 2-Cl-phenyl   H     CH.sub.3                                                                              7    Cl     OCH.sub.3                                                                            H                                 2-Cl-phenyl   H     H      7/9  OCH.sub.3                                                                             Cl    H                                 2-Cl-phenyl   H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl    H                                 2-F-phenyl    H     H      7/9  CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-F-phenyl    H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-F-phenyl    H     H      7/9  Cl     CH.sub.3                                                                             H                                 2-F-phenyl    H     CH.sub.3                                                                              7    Cl     CH.sub.3                                                                             H                                 2-F-phenyl    H     H      7/9  CH.sub.3                                                                              Cl    H                                 2-F-phenyl    H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl    H                                 2-F-phenyl    H     H      7/9  Cl     Cl    H                                 2-F-phenyl    H     CH.sub.3                                                                              7    Cl     Cl    H                                 2-F-phenyl    H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-F-phenyl    H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-F-phenyl    H     H      7/9  CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-F-phenyl    H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-F-phenyl    H     H      7/9  OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-F-phenyl    H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-F-phenyl    H     H      7/9  Cl     OCH.sub.3                                                                            H                                 2-F-phenyl    H     CH.sub.3                                                                              7    Cl     OCH.sub.3                                                                            H                                 2-F-phenyl    H     H      7/9  OCH.sub.3                                                                             Cl    H                                 2-F-phenyl    H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl    H                                 2-CH.sub. 3 -phenyl                                                                          H     H      7/9  CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-CH.sub.3 -phenyl                                                                           H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-CH.sub.3 -phenyl                                                                           H     H      7/9  Cl     CH.sub.3                                                                             H                                 2-CH.sub.3 -phenyl                                                                           H     CH.sub.3                                                                              7    Cl     CH.sub.3                                                                             H                                 2-CH.sub.3 -phenyl                                                                           H     H      7/9  CH.sub.3                                                                              Cl    H                                 2-CH.sub.3 -phenyl                                                                           H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl    H                                 2-CH.sub.3 -phenyl                                                                           H     H      7/9  Cl     Cl    H                                 2-CH.sub.3 -phenyl                                                                           H     CH.sub.3                                                                              7    Cl     Cl    H                                 2-CH.sub.3 -phenyl                                                                           H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-CH.sub.3 -phenyl                                                                           H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-CH.sub.3 -phenyl                                                                           H     H      7/9  CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-CH.sub.3 -phenyl                                                                           H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-CH.sub.3 -phenyl                                                                           H     H      7/9  OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-CH.sub.3 -phenyl                                                                           H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-CH.sub.3 -phenyl                                                                           H     H      7/9  Cl     OCH.sub.3                                                                            H                                 2-CH.sub.3 -phenyl                                                                           H     CH.sub.3                                                                              7    Cl     OCH.sub.3                                                                            H                                 2-CH.sub.3 -phenyl                                                                           H     H      7/9  OCH.sub.3                                                                             Cl    H                                 2-CH.sub.3 -phenyl                                                                           H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl    H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     H      7/9  CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     H      7/9  Cl     CH.sub.3                                                                             H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     CH.sub.3                                                                              7    Cl     CH.sub.3                                                                             H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     H      7/9  CH.sub.3                                                                              Cl    H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl    H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     H      7/9  Cl     Cl    H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     CH.sub.3                                                                              7    Cl     Cl    H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     H      7/9  CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     H      7/9  OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     H      7/9  Cl     OCH.sub.3                                                                            H                                 2-CO.sub.2 CH.sub. 3 -phenyl                                                                 H     CH.sub.3                                                                              7    Cl     OCH.sub.3                                                                            H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     H      7/9  OCH.sub.3                                                                             Cl    H                                 2-CO.sub.2 CH.sub.3 -phenyl                                                                  H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl    H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     H      7/9  CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     H      7/9  Cl     CH.sub.3                                                                             H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     CH.sub.3                                                                              7    Cl     CH.sub.3                                                                             H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     H      7/9  CH.sub.3                                                                              Cl    H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl    H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     H      7/9  Cl     Cl    H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     CH.sub.3                                                                              7    Cl     Cl    H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     H      7/9  CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-CO.sub.2 C.sub. 2 H.sub.5 -phenyl                                                          H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     H      7/9  OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     H      7/9  Cl     OCH.sub.3                                                                            H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     CH.sub.3                                                                              7    Cl     OCH.sub.3                                                                            H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     H      7/9  OCH.sub.3                                                                             Cl    H                                 2-CO.sub.2 C.sub.2 H.sub.5 -phenyl                                                           H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl    H                                 2-OCH.sub.3 -phenyl                                                                          H     H      7/9  CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-OCH.sub.3 -phenyl                                                                          H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-OCH.sub.3 -phenyl                                                                          H     H      7/9  Cl     CH.sub.3                                                                             H                                 2-OCH.sub.3 -phenyl                                                                          H     CH.sub.3                                                                              7    Cl     CH.sub.3                                                                             H                                 2-OCH.sub.3 -phenyl                                                                          H     H      7/9  CH.sub.3                                                                              Cl    H                                 2-OCH.sub.3 -phenyl                                                                          H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl    H                                 2-OCH.sub.3 -phenyl                                                                          H     H      7/9  Cl     Cl    H                                 2-OCH.sub.3 -phenyl                                                                          H     CH.sub.3                                                                              7    Cl     Cl    H                                 2-OCH.sub.3 -phenyl                                                                          H     H      7/9  OCH.sub. 3                                                                            OCH.sub.3                                                                            H                                 2-OCH.sub.3 -phenyl                                                                          H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-OCH.sub.3 -phenyl                                                                          H     H      7/9  CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-OCH.sub.3 -phenyl                                                                          H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-OCH.sub.3 -phenyl                                                                          H     H      7/9  OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-OCH.sub.3 -phenyl                                                                          H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-OCH.sub.3 -phenyl                                                                          H     H      7/9  Cl     OCH.sub.3                                                                            H                                 2-OCH.sub.3 -phenyl                                                                          H     CH.sub.3                                                                              7    Cl     OCH.sub.3                                                                            H                                 2-OCH.sub.3 -phenyl                                                                          H     H      7/9  OCH.sub.3                                                                             Cl    H                                 2-OCH.sub.3 -phenyl                                                                          H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl    H                                 2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     H      7/9  CH.sub.3                                                                              CH.sub.3                                                                             H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                                                                             H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     H      7/9  Cl     CH.sub.3                                                                             H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     CH.sub.3                                                                              7    Cl     CH.sub.3                                                                             H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     H      7/9  CH.sub.3                                                                              Cl    H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl    H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     H      7/9  Cl     Cl    H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     CH.sub.3                                                                              7    Cl     Cl    H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     H      7/9  CH.sub.3                                                                              OCH.sub.3                                                                            H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                                                                            H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     H      7/9  OCH.sub.3                                                                             CH.sub.3                                                                             H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                                                                             H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     H      7/9  Cl     OCH.sub.3                                                                            H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     CH.sub.3                                                                              7    Cl     OCH.sub.3                                                                            H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     H      7/9  OCH.sub.3                                                                             Cl    H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 OCH.sub.3 -                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl    H                                 phenyl                                                                         2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     H      7/9  CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     H      7/9  Cl     CH.sub.3                                                                             H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     CH.sub.3                                                                              7    Cl     CH.sub.3                                                                             H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     H      7/9  CH.sub.3                                                                              Cl    H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl    H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     H      7/9  Cl     Cl    H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     CH.sub.3                                                                              7    Cl     Cl    H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     H      7/9  CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     H      7/9  OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     H      7/9  Cl     OCH.sub.3                                                                            H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     CH.sub.3                                                                              7    Cl     OCH.sub.3                                                                            H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     H      7/9  OCH.sub.3                                                                             Cl    H                                 2-OCH.sub.2 CH.sub.2 Cl-phenyl                                                               H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl    H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     H      7/9  CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     H      7/9  Cl     CH.sub.3                                                                             H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     CH.sub.3                                                                              7    Cl     CH.sub.3                                                                             H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     H      7/9  CH.sub.3                                                                              Cl    H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl    H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     H      7/9  Cl     Cl    H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     CH.sub.3                                                                              7    Cl     Cl    H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     H      7/9  CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     H      7/9  OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     H      7/9  Cl     OCH.sub.3                                                                            H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     CH.sub.3                                                                              7    Cl     OCH.sub.3                                                                            H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     H      7/9  OCH.sub.3                                                                             Cl    H                                 2-OCH.sub.2 CO.sub.2 CH.sub.3 -phenyl                                                        H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl    H                                 2,6-Cl,Cl-phenyl                                                                             H     H      7/9  CH.sub.3                                                                              CH.sub.3                                                                             H                                 2,6-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                                                                             H                                 2,6-Cl,Cl-phenyl                                                                             H     H      7/9  Cl     CH.sub.3                                                                             H                                 2,6-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    Cl     CH.sub.3                                                                             H                                 2,6-Cl,Cl-phenyl                                                                             H     H      7/9  CH.sub.3                                                                              Cl    H                                 2,6-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl    H                                 2,6-Cl,Cl-phenyl                                                                             H     H      7/9  Cl     Cl    H                                 2,6-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    Cl     Cl    H                                 2,6-Cl,Cl-phenyl                                                                             H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2,6-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2,6-Cl,Cl-phenyl                                                                             H     H      7/9  CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2,6-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2,6-Cl,Cl-phenyl                                                                             H     H      7/9  OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2,6-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2,6-Cl,Cl-phenyl                                                                             H     H      7/9  Cl     OCH.sub.3                                                                            H                                 2,6-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    Cl     OCH.sub.3                                                                            H                                 2,6-Cl,Cl-phenyl                                                                             H     H      7/9  OCH.sub.3                                                                             Cl    H                                 2,6-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl    H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     H      7/9  CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                                                                             H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     H      7/9  Cl     CH.sub.3                                                                             H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     CH.sub.3                                                                              7    Cl     CH.sub.3                                                                             H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     H      7/9  CH.sub.3                                                                              Cl    H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl    H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     H      7/9  Cl     Cl    H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     CH.sub.3                                                                              7    Cl     Cl    H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     H      7/9  CH.sub. 3                                                                             OCH.sub.3                                                                            H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     H      7/9  OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     H      7/9  Cl     OCH.sub.3                                                                            H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     CH.sub.3                                                                              7    Cl     OCH.sub.3                                                                            H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     H      7/9  OCH.sub.3                                                                             Cl    H                                 2-Cl,6-CH.sub.3 -phenyl                                                                      H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl    H                                 2,5-Cl,Cl-phenyl                                                                             H     H      7/9  CH.sub.3                                                                              CH.sub.3                                                                             H                                 2,5-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              CH.sub.3                                                                             H                                 2,5-Cl,Cl-phenyl                                                                             H     H      7/9  Cl     CH.sub.3                                                                             H                                 2,5-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    Cl     CH.sub.3                                                                             H                                 2,5-Cl,Cl-phenyl                                                                             H     H      7/9  CH.sub.3                                                                              Cl    H                                 2,5-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              Cl    H                                 2,5-Cl,Cl-phenyl                                                                             H     H      7/9  Cl     Cl    H                                 2,5-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    Cl     Cl    H                                 2,5-Cl,Cl-phenyl                                                                             H     H      7/9  OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2,5-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             OCH.sub.3                                                                            H                                 2,5-Cl,Cl-phenyl                                                                             H     H      7/9  CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2,5-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    CH.sub.3                                                                              OCH.sub.3                                                                            H                                 2,5-Cl,Cl-phenyl                                                                             H     H      7/9  OCH.sub. 3                                                                            CH.sub.3                                                                             H                                 2,5-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             CH.sub.3                                                                             H                                 2,5-Cl,Cl-phenyl                                                                             H     H      7/9  Cl     OCH.sub.3                                                                            H                                 2,5-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    Cl     OCH.sub.3                                                                            H                                 2,5-Cl,Cl-phenyl                                                                             H     H      7/9  OCH.sub.3                                                                             Cl    H                                 2,5-Cl,Cl-phenyl                                                                             H     CH.sub.3                                                                              7    OCH.sub.3                                                                             Cl    H                                 ______________________________________                                    

The substituted sulfonamides I, and herbicidal agents containing them, may be applied for instance in the form of directly sprayable solutions, powders, suspensions (including high-percentage aqueous, oily or other suspensions); dispersions, emulsions, oil dispersions, pastes, dusts, broadcasting agents, or granules by spraying, atomizing, dusting, broadcasting or watering. The forms of application depend entirely on the purpose for which the agents are being used, but they must ensure as fine a distribution of the active ingredients according to the invention as possible.

For the preparation of solutions, emulsions, pastes and oil dispersions to be sprayed direct, mineral oil fractions of medium to high boiling point, such as kerosene or diesel oil, further coal-tar oils, and oils of vegetable or animal origin, aliphatic, cyclic and aromatic hydrocarbons such as toluene, xylene, paraffin, tetrahydronaphthalene, alkylated naphthalenes and their derivatives, methanol, ethanol, propanol, butanol, cyclohexanol, cyclohexanone, chlorobenzene, isophorone, etc., and strongly polar solvents such as N,N-dimethylformamide, dimethyl sulfoxide, N-methylpyrrolidone, water, etc. are suitable.

Aqueous formulations may be prepared from emulsion concentrates, pastes, oil dispersions, wettable powders or water-dispersible granules by adding water. To prepare emulsions, pastes and oil dispersions the ingredients as such or dissolved in an oil or solvent may be homogenized in water by means of wetting or dispersing agents, adherents or emulsifiers. Concentrates which are suitable for dilution with water may be prepared from active ingredient, wetting agent, adherent, emulsifying or dispersing agent and possibly solvent or oil.

Examples of surfactants are: alkali metal, alkaline earth metal and ammonium salts of aromatic sulfonic acids, e.g., ligninsulfonic acid, phenolsulfonic acid, naphthalenesulfonic acid and dibutylnaphthalenesulfonic acid, and of fatty acids, alkyl and alkylaryl sulfonates, and alkyl, lauryl ether and fatty alcohol sulfates, and salts of sulfated hexadecanols, heptadecanols, and octadecanols, salts of fatty alcohol glycol ethers, condensation products of sulfonated naphthalene and naphthalene derivatives with formaldehyde, condensation products of naphthalene or naphthalenesulfonic acids with phenol and formaldehyde, polyoxyethylene octylphenol ethers, ethoxylated isooctylphenol, ethoxylated octylphenol and ethoxylated nonylphenol, alkylphenol polyglycol ethers, tributylphenyl polyglycol ethers, alkylaryl polyether alcohols, isotridecyl alcohol, fatty alcohol ethylene oxide condensates, ethoxylated castor oil, polyoxyethylene alkyl ethers, ethoxylated polyoxypropylene, lauryl alcohol polyglycol ether acetal, sorbitol esters, lignin-sulfite waste liquors and methyl cellulose.

Powders, dusts and broadcasting agents may be prepared by mixing or grinding the active ingredients with a solid carrier.

Granules, e.g., coated, impregnated or homogeneous granules, may be prepared by bonding the active ingredients to solid carriers. Examples of solid carriers are mineral earths such as silicic acids, silica gels, silicates, talc, kaolin, attapulgus clay, limestone, lime, chalk, bole, loess, clay, dolomite, diatomaceous earth, calcium sulfate, magnesium sulfate, magnesium oxide, ground plastics, fertilizers such as ammonium sulfate, ammonium phosphate, ammonium nitrate, and ureas, and vegetable products such as grain meals, bark meal, wood meal, and nutshell meal, cellulosic powders, etc.

The formulations contain from 0.1 to 95, and preferably 0.5 to 90, % by weight of active ingredient.

Examples of formulations are as follows

I. 90 parts by weight of compound no. 1.005 is mixed with 10 parts by weight of N-methyl-alpha-pyrrolidone. A mixture is obtained which is suitable for application in the form of very fine drops.

II. 20 parts by weight of compound no. 1.006 is dissolved in a mixture consisting of 80 parts by weight of xylene, 10 parts by weight of the adduct of 8 to 10 moles of ethylene oxide and 1 mole of oleic acid-N-monoethanolamide, 5 parts by weight of the calcium salt of dodecylbenzenesulfonic acid, and 5 parts by weight of the adduct of 40 moles of ethylene oxide and 1 mole of castor oil. By pouring the solution into 100,000 parts by weight of water and uniformly distributing it therein, an aqueous dispersion is obtained containing 0.02% by weight of the active ingredient.

III. 20 parts by weight of compound no. 1.007 is dissolved in a mixture consisting of 40 parts by weight of cyclohexanone, 30 parts by weight of isobutanol, 20 parts by weight of the adduct of 7 moles of ethylene oxide and 1 mole of isooctylphenol, and 10 parts by weight of the adduct of 40 moles of ethylene oxide and 1 mole of castor oil. By pouring the solution into 100,000 parts by weight of water and finely distributing it therein, an aqueous dispersion is obtained containing 0.02% by weight of the active ingredient.

IV. 20 parts by weight of compound no. 1.008 is dissolved in a mixture consisting of 25 parts by weight of cyclohexanone, 65 parts by weight of a mineral oil fraction having a boiling point between 210° and 280° C., and 10 parts by weight of the adduct of 40 moles of ethylene oxide and 1 mole of castor oil. By pouring the solution into 100,000 parts by weight of water and uniformly distributing it therein, an aqueous dispersion is obtained containing 0.02% by weight of the active ingredient.

V. 20 parts by weight of compound no. 1.009 is well mixed with 3 parts by weight of the sodium salt of diisobutylnaphthalene-alpha-sulfonic acid, 17 parts by weight of the sodium salt of a lignin-sulfonic acid obtained from a sulfite waste liquor, and 60 parts by weight of powdered silica gel, and triturated in a hammer mill. By uniformly distributing the mixture in 20,000 parts by weight of water, a spray liquor is obtained containing 0.1% by weight of the active ingredient.

VI. 3 parts by weight of compound no. 1.010 is intimately mixed with 97 parts by weight of particulate kaolin. A dust is obtained containing 3% by weight of the active ingredient.

VII. 30 parts by weight of compound no. 1.011 is intimately mixed with a mixture consisting of 92 parts by weight of powdered silica gel and 8 parts by weight of paraffin oil which has been sprayed onto the surface of this silica gel. A formulation of the active ingredient is obtained having good adherence.

VIII. 20 parts by weight of compound no. 1.012 is intimately mixed with 2 parts of the calcium salt of dodecylbenzenesulfonic acid, 8 parts of a fatty alcohol polyglycol ether, 2 parts of the sodium salt of a phenolsulfonic acid-urea-formaldehyde condensate and 68 parts of a paraffinic mineral oil. A stable oily dispersion is obtained.

The active ingredients or the herbicidal agents containing them may be applied pre- or postemergence. If certain crop plants tolerate the active ingredients less well, application techniques may be used in which the herbicidal agents are sprayed from suitable equipment in such a manner that the leaves of sensitive crop plants are if possible not touched, and the agents reach the soil or the unwanted plants growing beneath the crop plants (post-directed, lay-by treatment).

The application rates depend on the objective to be achieved, the time of the year, the plants to be combated and their growth stage, and are from 0.001 to 3.0, preferably 0.01 to 1.0, kg of active ingredient per hectare.

In view of the numerous application methods possible, the compounds according to the invention, or agents containing them, may be used in a large number of crops for removing unwanted plants.

Some of the sulfonamides of the general formula I may exercise a variety of influences on practically all plant development stages, and are therefore used as growth regulators. The diversity of action of growth regulators depends especially on

a) the type and variety of plant;

b) the time applied, with reference to the development stage of the plants and the time of the year;

c) the place and method of application (seed treatment, soil treatment, or application to foliage);

d) climatic factors, e.g., average temperature, amount of precipitate, sunshine and duration;

e) soil conditions (including fertilization);

f) the formulation of the active ingredient; and

g) the concentration at which the active ingredient is applied.

A description of some of the various possibilities of using the growth regulators according to the invention in agriculture and horticulture is given below.

A. Vegetative plant growth can be inhibited to a considerable extent, a fact which is manifested particularly in a reduction in plant height. The treated plants thus have a compact habit; furthermore, the leaf color is darker.

Of advantage in practice is for example the reduction in grass growth on roadsides, hedges, canal embankments and on areas such as parks, sportsgrounds, fruit orchards, lawns and airfields, thus reducing expensive and time-consuming mowing.

A further feature of economic interest is the increase in the rigor of crops which tend to lodge, such as cereals, Indian corn, sunflowers and soybeans. The shortening and strengthening of the stem thus caused reduces or eliminates the danger of lodging under unfavorable weather conditions.

Of practical importance is the reduction in vegetative growth in fruit trees and other woody plants, thus saving pruning costs.

The use of growth regulators is also important for inhibiting plant height and changing the time of ripening in cotton. It is thus possible for this important crop to be harvested completely mechanically.

Growth regulators may also increase or inhibit lateral branching. This is of interest when, for instance in tobacco plants, it is desired to inhibit the formation of lateral shoots (suckers) in favor of leaf development.

With growth regulators, it is possible for instance in winter rape to considerably increase the resistance to freeze injury. On the one hand, upward growth and the development of a too luxuriant (and thus particularly frost-susceptible) leaf or plant mass are inhibited; on the other, the young rape plants are kept, in spite of favorable growth conditions, in the vegetative development stage before winter frosts begin. The danger of freeze injury is thus eliminated in plants which tend to lose prematurely their inhibition to bloom and pass into the generative phase. In other crops, too, e.g., winter cereals, it is advantageous if the plants are well tillered in the fall as a result of treatment with the compounds according to the invention, but enter winter with not too lush a growth. This is a preventive measure against increased susceptibility to freeze injury and--because of the relatively low leaf or plant mass--attack by various (especially fungus) diseases. The inhibition of vegetative growth also makes closer planting possible in numerous crops, which means an increase in yield, based on the area cropped.

B. Better yields both of plant parts and plant materials may be obtained with the novel agents. It is thus for instance possible to induce increased formation of buds, blossom, leaves, fruit, seed grains, roots and tubers, to increase the sugar content of sugarbeets, sugarcane and citrus fruit, to raise the protein content of cereals and soybeans, and to stimulate the increased formation of latex in rubber trees.

The sulfonamides of the formula I may raise the yield by influencing plant metabolism or by promoting or inhibiting vegetative and/or generative plant growth. C. It is also possible with growth regulators to shorten or lengthen growth stages and to accelerate or retard the ripening process in plant parts either before or after harvesting.

A factor of economic interest is for example the facilitation of harvesting made possible by a chemical, temporally concentrated loosening (abscission) of the adherence of stalks to the branches of citrus fruit, olive trees, and other kinds of pomes, drupes and indehiscent fruit. The same mechanism, i.e., promotion of the formation of separation layers between fruit or leaf and stem of the plant, is also essential for a readily controllable defoliation of crop plants, e.g., cotton.

D. Further, transpiration in crop plants may be reduced with growth regulators. This is particularly important for plants growing in agricultural areas which are expensive to irrigate, e.g., in arid or semi-arid areas. Irrigation frequency can be reduced by using the compounds according to the invention, making for lower costs. As a result of the use of growth regulators, the water available can be better utilized, because, inter alia,

the size of the stomata opening is reduced;

a thicker epidermis and cuticle are formed;

penetration of the soil by the roots is improved;

the micro-climate in the stand is favorably influenced by the more compact growth.

The active ingredients according to the invention may be applied not only to the seed (as a disinfectant), but also to the soil, i.e., via the roots, and to the foliage by spraying.

As a result of the good tolerance by crop plants, the application rate when the active ingredients are used as growth regulators may vary within wide limits.

When the active ingredients are used for treating seed, amounts of from 0.001 to 50, and preferably from 0.01 to 1, g per kg of seed are generally required. For foliage and soil treatment, amounts of from 0.01 to 10, and preferably from 0.1 to 5, kg/ha are generally considered to be sufficient.

To increase the spectrum of action and to achieve synergistic effects, the sulfonamides of the formula I may be mixed with each other, or mixed and applied together with numerous representatives of other herbicidal or growth-regulating active ingredient groups. Examples of suitable components are diazines, 4H-3,1-benzoxazine derivatives, benzothiadiazinones, 2,6-dinitroanilines, N-phenylcarbamates, thiolcarbamates, halocarboxylic acids, triazines, amides, ureas, diphenyl ethers, triazinones, uracils, benzofuran derivatives, imidazolinones, sulfonylureas, cyclohexane-1,3-dione derivatives, quinolinecarboxylic acid derivatives, phenyloxy- or (hetero)-aryloxyphenylpropionic acid derivatives (salts, esters, amides), etc.

It may also be useful to apply the novel compounds of the formula I, either alone or in combination with other herbicides, in admixture with other crop protection agents, e.g., agents for combating pests or phytopathogenic fungi or bacteria. The compounds may also be mixed with solutions of mineral salts used to remedy nutritional or trace element deficiencies. Non-phytotoxic oils and oil concentrates may also be added.

The directions given in the synthesis examples below were used, after appropriate modifications of the starting materials, to produce further compounds I. The compounds obtained are given in Tables 1 to 3 with their physical data.

EXAMPLE 1 Synthesis of N¹ -(2,6-dichloro-7-methyl-8-purinyl)-benzenesulfonamide (process A)

10.8 g (50.0 mmol) of the sodium salt of benzenesulfonamide was suspended in 100 ml of DMF; at 60° C., 11.9 g (50.0 mmol) of 7-methyl-2,6,8-trichloropurine was added. After 8 hours at 80° C. and cooling to room temperature, H₂ O/ice was added, the mixture was acidified with 10% strength hydrochloric acid and the precipitate was suction filtered and dried.

11.7 g of colorless crystals (65%) (active ingredient 1.001).

¹ H-NMR (250 MHz, d⁶ DMSO, δ in ppm): 3.60 (s, 3H, N-CH₃); 7.60 (mc, 3H, aryl-H); 7.95 (mc, 2H, aryl-H).

EXAMPLE 2 Synthesis of N¹ -(2-chloro-6-methoxy-7-methyl-8-purinyl)-benzenesulfonamide (process F)

3.00 g (8.00 mmol) of the sulfonamide prepared in Example 1 and 2.90 g (16.0 mmol) of 30% strength sodium methylate solution were stirred in 50 ml of methanol for 12 hours at room temperature, and then evaporated down in a rotary evaporator. Stirring the residue in H₂ O and acidifying with dilute HCl gave 2.30 g (81%) of the desired product in the form of colorless crystals (active ingredient 1.002).

¹ H-NMR (250 MHz, d⁶ -DMSO, δ in ppm): 3.50 (s, 3H, N-CH₃); 4.05 (s, 3H, OCH₃); 7.55 (mc, 3H, aryl-H); 7.95 (mc, 2H, aryl-H).

EXAMPLE 3 Synthesis of N¹ -(2,6-dimethoxy-7-methyl-8-purinyl)-benzenesulfonamide (process G)

3.60 g (10.0 mmol) of the sulfonamide synthesized in Example 1 and 5.40 g (30.0 mmol) of 30% strength sodium methylate solution were heated in 200 ml of methanol in an autoclave for 12 hours at 120° C.; after the mixture had been cooled to room temperature it was evaporated in a rotary evaporator. Stirring the residue in H₂ O and acidifying with 10% strength HCl gave 3.20 g of colorless crystals in a yield of 92% (active ingredient 1.003).

¹ H-NMR (250 MHz, d⁶ -DMSO, δ in ppm): 3.45 (s, 3H, N-CH₃); 3.90 (s, 3H, OCH₃); 4.05 (s, 3H, OCH₃); 7.50 (mc, 3H, aryl-H); 7.95 (mc, 2H, aryl-H).

EXAMPLE 4 Synthesis of N¹ -(2,6-dichloro-7-methyl-8-purinyl)-2-carbomethoxybenzenesulfonamide (process B)

At 70° C., 6.60 g (28 mmol) of 2-carbomethoxybenzenesulfonamide was added to a suspension of 3.00 g (14.0 mmol) of 8-amino-2,6-dichloro-7-methylpurine in 150 ml of pyridine. After 3 hours at 70°-80° C., the reaction mixture was evaporated down in a rotary evaporator, and the residue was stirred into ice/H₂ O and acidified with dilute HCl. The desired product was obtained in the form of a brown powder having the following physical data (active ingredient 1.020)

¹ H-NMR (250 MHz, d⁶ -DMSO, δ in ppm): 3.60 (s, 3H, N-CH₃); 3.80 (s, 3H, CO₂ CH₃); 7.60 (mc, 1H, aryl-H); 7.70 (mc, 2H, aryl-H); 8.10 (mc, 1H, aryl-H).

EXAMPLE 5 Synthesis of N¹ -(2,6-dimethoxy-8-purinyl)-benzenesulfonamide (process C)

While stirring and at room temperature, 3.00 g (13.0 mmol) of benzenesulfonylisocyanide dichloride was slowly dripped into 2.20 (13.0 mmol) of 4,5-diamino-2,6-dimethoxypyrimidine and 2.60 g (26.0 mmol) of triethylamine in 50 ml of dioxane. After 5 hours at 100° C., the mixture was cooled to room temperature, the solid which had formed was filtered off and the filtrate was evaporated down in a rotary evaporator. The desired product was isolated from the residue by crystallization with methylene chloride/methyl tert-butyl ether (active ingredient 1.004).

¹ H-NMR (250 MHz, d⁶ -DMSO, δ in ppm): 3.90 (s, 3H, OCH₃); 4.00 (s, 3H, OCH₃); 7.55 (mc, 3H, aryl-H); 7.95 (mc, 2H, aryl-H).

                                      TABLE 1                                      __________________________________________________________________________      ##STR18##                                            Ia                       No.                                                                               A         R.sup.1                                                                          R.sup.2                                                                           R.sup.3                                                                             R.sup.4                                                                            .sup.1 HNMR[d.sup.6 DMSO, δ(ppm)];                                       mp[°C.]                                      __________________________________________________________________________     1.001                                                                             phenyl    H CH.sub.3                                                                          Cl   Cl  3.60(s, 3H); 7.60(mc, 3H); 7.95(mc, 2H);            1.002                                                                             phenyl    H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.50(s, 3H); 4.05(s, 3H); 7.55(mc, 3H);                                        7.95(mc, 2H)                                        1.003                                                                             phenyl    H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          3.45(s, 3H); 3.90(s, 3H); 4.05(s, 3H);                                         7.50(mc, 3H);                                                                  7.95(mc, 2H);                                       1.004                                                                             phenyl    H H  OCH.sub.3                                                                           OCH.sub.3                                                                          3.90(s, 3H); 4.00(s, 3H); 7.55(mc, 3H);                                        7.95(mc, 2H);                                       1.005                                                                             2-Cl-phenyl                                                                              H CH.sub.3                                                                          Cl   Cl  3.60(s, 3H); 7.50-7.60(m, 3H); 8.15(mc, 1H);        1.006                                                                             2-Cl-phenyl                                                                              H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.55(s, 3H); 4.05(s, 3H); 7.45-7.60(m, 3H);                                    8.15(mc, 1H);                                       1.007                                                                             2-Cl-phenyl                                                                              H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          3.50(s, 3H); 3.90(s, 3H); 4.05(s, 3H);                                         7.45-7.60(m, 3H); 8.15(mc, 1H);                     1.008                                                                             2,6-Cl,Cl-phenyl                                                                         H CH.sub.3                                                                          Cl   Cl  3.60(s, 3H); 7.45-7.60(m, 3H);                      1.009                                                                             2,6-Cl,Cl-phenyl                                                                         H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.55(s, 3H); 4.10(s, 3H); 7.50-7.65(m, 3H);         1.010                                                                             2,6-Cl,Cl-phenyl                                                                         H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          3.50(s, 3H); 3.80(s, 3H); 3.95(s, 3H);                                         7.40-7.50(m, 3H);                                   1.011                                                                             2,6-Cl,Cl-phenyl                                                                         H CH.sub.3                                                                          N(CH.sub.3).sub.2                                                                   Cl  3.05(s, 6H); 3.55(s, 3H); 7.40-7.55(m, 3H);         1.012                                                                             2,5-Cl,Cl-phenyl                                                                         H CH.sub.3                                                                          Cl   Cl  3.60(s, 3H); 7.60(mc, 2H); 8.20(mc, 1H);            1.013                                                                             2,5-Cl,Cl-phenyl                                                                         H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.55(s, 3H); 4.05(s, 3H); 7.65(mc, 2H);                                        8.20(mc, 1H);                                       1.014                                                                             2,5-Cl,Cl-phenyl                                                                         H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          3.55(s, 3H); 3.90(s, 3H); 4.05(s, 3H);                                         7.65(mc, 2H);                                                                  8.20(mc, 1H);                                       1.015                                                                             3-F-phenyl                                                                               H CH.sub.3                                                                          Cl   Cl  3.65(s, 3H); 7.40(mc, 1H); 7.60(mc, 1H);                                       7.80(mc, 2H);                                       1.016                                                                             3-F-phenyl                                                                               H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.50(s, 3H); 4.10(s, 3H); 7.40(mc, 1H);                                        7.60(mc, 1H);                                                                  7.80(mc, 2H);                                       1.017                                                                             3-F-phenyl                                                                               H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          3.50(s, 3H); 3.90(s, 3H); 4.00(s, 3H);                                         7.40(mc, 1H);                                                                  7.60(mc, 1H); 7.80(mc, 2H);                         1.018                                                                             4-F-phenyl                                                                               H CH.sub.3                                                                          Cl   Cl  3.60(s, 3H); 7.40(mc, 2H); 8.05(mc, 2H);            1.019                                                                             4-F-phenyl                                                                               H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.50(s, 3H); 4.05(s, 3H); 7.30(mc, 2H);                                        8.00(mc, 2H);                                       1.020                                                                             2-CO.sub.2 CH.sub.3 -phenyl                                                              H CH.sub.3                                                                          Cl   Cl  3.60(s, 3H); 3.80(s, 3H); 7.60(mc, 1H);                                        7.70(mc, 2H);                                                                  8.10(mc, 1H);                                       1.021                                                                             2-Cl,6-CH.sub.3 -phenyl                                                                  H CH.sub.3                                                                          Cl   Cl  2.70(s, 3H); 3.55(s, 3H); 7.30-7.50(m, 3H);         1.022                                                                             2-Cl,6-CH.sub.3 -phenyl                                                                  H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  2.70(s, 3H); 3.50(s, 3H); 4.00(s, 3H);                                         7.30-7.50(m, 3H);                                   1.023                                                                             2-Cl,6-CH.sub.3 -phenyl                                                                  H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          2.70(s, 3H); 3.50(s, 3H); 3.90(s, 3H); 4.00(s,                                 3H);                                                                           7.20-7.40(m, 3H);                                   1.024                                                                             2-OCH.sub.3 -phenyl                                                                      H CH.sub.3                                                                          Cl   Cl  3.55(s, 3H); 3.70(s, 3H); 7.05(t, 1H); 7.15(d,                                 1H);7.55                                                                       (t, 1H); 7.85(d, 1H);                               1.025                                                                             2-OCH.sub.3 -phenyl                                                                      H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.45(s, 3H); 3.65(s, 3H); 4.05(s, 3H); 7.05(t,                                 1H);                                                                           7.15(d, 1H); 7.55(t, 1H); 7.85(d, 1H);              1.026                                                                             2-OCH.sub.3 -phenyl                                                                      H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          3.45(s, 3H); 3.60(s, 3H); 3.90(s, 3H); 4.05(s,                                 3H);                                                                           7.00(t, 1H); 7.10(d, 1H); 7.50(t, 1H); 7.85(d,                                 1H);                                                1.027                                                                             2-OCH.sub.3 -phenyl                                                                      H CH.sub.3                                                                          N(CH.sub.3).sub.2                                                                   Cl  3.00(s, 6H); 3.45(s, 3H); 3.60(s, 3H); 7.05(t,                                 1H);                                                                           7.15(d, 1H); 7.55(t, 1H); 7.85(d, 1H);              1.028                                                                             4-OCH.sub.3 -phenyl                                                                      H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          3.50(s, 3H); 3.80(s, 3H); 3.90(s, 3H); 4.00(s,                                 3H);                                                                           6.95(mc, 2H); 7.90(mc, 2H);                         1.029                                                                             2-naphthyl                                                                               H CH.sub.3                                                                          Cl   Cl  3.60(s, 3H); 7.70(mc, 2H); 7.90-8.15(m, 4H);                                   8.65(s, 1H);                                        1.030                                                                             2-naphthyl                                                                               H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.50(s, 3H); 4.00(s, 3H); 7.55(mc, 2H);                                        7.90-8.15                                                                      (m, 4H); 8.65(s, 1H);                               1.031                                                                             2-naphthyl                                                                               H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          3.50(s, 3H); 3.85(s, 3H); 3.95(s, 3H);                                         7.60(mc, 2H);                                                                  7.90-8.10(m, 4H); 8.60(s, 1H);                      1.032                                                                             1-naphthyl                                                                               H CH.sub.3                                                                          Cl   Cl  3.55(s, 3H); 7.60-7.75(m, 3H); 8.00(mc, 1H);                                   8.15(mc, 1H);                                                                  8.40(mc, 1H); 8.80(mc, 1H);                         1.033                                                                             1-naphthyl                                                                               H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.45(s, 3H); 3.95(s, 3H); 7.55-7.70(m, 3H);                                    7.95(mc,                                                                       1H); 7.95(mc, 1H); 8.05(mc, 1H); 8.20(mc, 1H);                                 8.35(mc, 1H);                                                                  8.85(mc, 1H);                                       1.034                                                                             1-naphthyl                                                                               H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          3.50(s, 3H); 3.80(s, 3H); 3.90(s, 3H);                                         7.45-7.60                                                                      (m, 3H); 8.15(mc, 1H);                              1.035                                                                             8-quinolyl                                                                               H CH.sub.3                                                                          Cl   Cl  3.50(s, 3H); 7.65(mc, 1H); 7.80(mc, 1H);                                       8.30(mc, 1H);                                                                  8.50(mc, 1H); 8.55(mc, 1H); 8.80(mc, 1H);           1.036                                                                             8-quinolyl                                                                               H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.40(s, 3H); 4.10(s, 3H); 7.55(mc, 1H);                                        7.70(mc, 1H);                                                                  8.20(mc, 1H); 8.50(mc, 2H); 8.70(mc, 1H);           1.037                                                                             2-thienyl H CH.sub.3                                                                          Cl   Cl  3.65(s, 3H); 7.10(mc, 1H); 7.75(mc, 1H);                                       7.85(mc, 1H);                                       1.038                                                                             2-thienyl H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.55(s, 3H); 4.05(s, 3H); 7.10(mc, 1H);                                        7.75(mc, 2H);                                       1.039                                                                             2-thienyl H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          3.50(s, 3H); 3.95(s, 3H); 4.05(s, 3H);                                         7.10(mc, 1H);                                                                  7.80(mc, 2H);                                       1.040                                                                             3-Cl,2-thienyl                                                                           H CH.sub.3                                                                          Cl   Cl  3.70(s, 3H); 7.10(d, 1H); 7.90(d, 1H);              1.041                                                                             3-Cl,2-thienyl                                                                           H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.50(s, 3H),4.10(s, 3H); 7.10(d, 1H); 7.90(d,                                  1H);                                                1.042                                                                             3-Cl,2-thienyl                                                                           H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          3.55(s, 3H); 3.90(s, 3H); 4.05(s, 3H); 7.10(d,                                 1H),                                                                           7.85(d, 1H);                                        1.043                                                                             4-CO.sub.2 CH.sub.3,3-thienyl                                                            H CH.sub.3                                                                          Cl   Cl  3.55(s, 3H); 3.70(s, 3H); 8.35(mc, 2H);             1.044                                                                             4-CO.sub.2 CH.sub.3,3-thienyl                                                            H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.50(s, 3H); 3.70(s, 3H); 4.10(s, 3H);                                         8.30(mc, 2H);                                       1.045                                                                             4-CO.sub.2 CH.sub.3,3-thienyl                                                            H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          3.45(s, 3H); 3.70(s, 3H); 3.90(s, 3H); 4.05(s,                                 3H)                                                                            8.30(mc, 2H);                                       1.046                                                                             2-chlorophenyl                                                                           H H  OCH.sub.3                                                                           CH.sub.3                                                                           2.48(s, 3H); 34.00s, 3H); 7.51(mc, 3H);                                        8.19(d, 1H);                                                                   12.50(s; 1H); 12.70(s; 1H);                         1.047                                                                             2-chlorophenyl                                                                           H H  OCH.sub.3                                                                           OCH.sub.3                                                                          3.90(s, 3H); 4.05(s, 3H); 7.51(mc, 3H);                                        8.15(d, 1H);                                                                   12.30(s, 1H); 12.60(s, 1H);                         1.048                                                                             2-chlorophenyl                                                                           H CH.sub.3                                                                          F    F   193                                                 1.049                                                                             2-chlorophenyl                                                                           H CH.sub.3                                                                          OCH.sub.3                                                                           F   3.53(s, 3H); 7.37(mc, 2H); 7.63(mc, 1H);                                       7.97(mc, 1H);                                                                  13.0(m, 1H);                                        1.050                                                                             2,6-Cl,Cl-phenyl                                                                         H CH.sub.3                                                                          F    F   3.53(s, 3H); 7.22-7.63(m, 3H);                      1.051                                                                             2,6-Cl,Cl-phenyl                                                                         H CH.sub.3                                                                          OCH.sub.3                                                                           F   3.53(s, 3H); 7.51(mc, 1H); 7.60(mc, 2H);            1.052                                                                             2,6-Cl,Cl-phenyl                                                                         H CH.sub.3                                                                          OCH.sub.2 CF.sub.3                                                                  Cl  3.53(s, 3H); 5.19(q, 2H); 7.54(mc, 3H);             1.053                                                                             2,3-Cl,Cl-phenyl                                                                         H CH.sub. 3                                                                         Cl   Cl  244                                                 1.054                                                                             2,3-Cl,Cl-phenyl                                                                         H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  215                                                 1.055                                                                             2,4,5,-Cl,Cl,Cl-                                                                         H CH.sub.3                                                                          Cl   Cl  255-227                                                phenyl                                                                      1.056                                                                             2-F-phenyl                                                                               H CH.sub.3                                                                          Cl   Cl  115-119                                             1.057                                                                             2-F-phenyl                                                                               H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  210-212                                             1.058                                                                             2-F-phenyl                                                                               H CH.sub.3                                                                          F    F   3.53(s, 33H); 7.53(mc, 1H); 7.64(mc, 2H);                                      8.19(d, 1H);                                        1.059                                                                             2,6-F,F-phenyl                                                                           H CH.sub.3                                                                          Cl   Cl  3.65(s, 3H); 7.63(mc, 1H); 8.05(mc, 1H);                                       8.91(mc, 1H);                                       1.060                                                                             2,6-F,F-phenyl                                                                           H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  *3.61(s, 3H); 4.15(s, 3H); 6.91(mc, 2H);                                       7.41(mc, 2H);                                       1.061                                                                             2.6-F,F-phenyl                                                                           H CH.sub.3                                                                          F    F   167-169                                             1.062                                                                             2.6-F,F-phenyl                                                                           H CH.sub.3                                                                          OCH.sub.3                                                                           F   3.56(s, 3H); 4.08(s, 3H); 7.23(mc, 2H);                                        7.64(mc, 2H);                                       1.063                                                                             2-CO.sub.2 CH.sub.3 -phenyl                                                              H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  203-205                                             1.064                                                                             2-CH.sub.3 -phenyl                                                                       H CH.sub.3                                                                          Cl   Cl  2.63(s, 3H); 3.61(s, 3H); 7.40(mc, 3H);                                        8.07(d, 1H);                                        1.065                                                                             2-CH.sub.3 -phenyl                                                                       H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  2.61(s, 3H); 3.49(s, 3H); 4.03(s, 3H);                                         7.39(mc, 3H);                                                                  8.05(d, 1H); 0.87(s, 1H);                           1.066                                                                             2-CH.sub.3 -phenyl                                                                       H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          2.63(s, 3H); 3.50(s, 3H); 3.89(s, 3H); 4.01(s,                                 3H);                                                                           7.38(mc, 3H); 8.09(d, 1H); 12.45(s, 1H);            1.067                                                                             2,5-CH.sub.3,CH.sub.3 -phenyl                                                            H CH.sub.3                                                                          Cl   Cl  189-190                                             1.068                                                                             2,5-CH.sub.3,CH.sub.3 -phenyl                                                            H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  206-208                                             1.069                                                                             2,5-CH.sub.3,CH.sub.3 -phenyl                                                            H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          182-184                                             1.070                                                                             2-CF.sub.3 -phenyl                                                                       H CH.sub.3                                                                          Cl   Cl  208-210                                             1.071                                                                             2-CF.sub.3 -phenyl                                                                       H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  205-206                                             1.072                                                                             2-CF.sub.3 -phenyl                                                                       H CH.sub.3                                                                          OCH.sub.3                                                                           OCH.sub.3                                                                          199-203                                             1.073                                                                             2-O(CH.sub.2).sub.2 Cl-phenyl                                                            H CH.sub.3                                                                          Cl   Cl  115-119                                             1.074                                                                             2-O(CH.sub.2).sub.2 OCH.sub.3 -                                                          H CH.sub.3                                                                          Cl   Cl  191-193                                                phenyl                                                                      1.075                                                                             2-O(CH.sub.2).sub.2 OCH.sub.3 -                                                          H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  188                                                    phenyl                                                                      1.076                                                                             2,5-OCH.sub.3,OCH.sub.3 -                                                                H CH.sub.3                                                                          Cl   Cl  3.54(s, 3H); 3.61(s, 3H):3.76(s, 3H); 7.11(s,                                  2H);                                                   phenyl                  7.44(s, 1H); 12.85(s, 1H);                          1.077                                                                             2,5-OCH.sub.3,OCH.sub.3 -                                                                H CH.sub.3                                                                          OCH.sub.3                                                                           Cl  3.46(s, 3H); 3.61(s, 3H); 3.76(s, 3H); 4.04(s,                                 3H);                                                   phenyl                  7.07(s, 2H); 7.44(s, 1, H); 12.62(s, 1H);           1.078                                                                             2-OCH.sub.3,5-Br-phenyl                                                                  H CH.sub.3                                                                          Cl   Cl  3.57(s, 3H); 3.71(s-3H); 7.13(mc, 1H);                                         7.73(mc-1H);                                                                   7.98(mc, 1H);                                       __________________________________________________________________________      *.sup.1 H NMR spectrum using CDCl.sub.3 as solvent                       

                                      TABLE 2                                      __________________________________________________________________________      ##STR19##                               Ib                                    No.                                                                               A        R.sup.1                                                                          R.sup.2                                                                           R.sup.3                                                                            R.sup.4                                                                          .sup.1 HNMR[d.sup.6 DMSO, δ(ppm)];                                       mp[°C.]                                          __________________________________________________________________________     2.001                                                                             2,6-Cl,Cl-phenyl                                                                        H CH.sub.3                                                                          Cl  Cl                                                                               3.60(s, 3H); 4.70(s, 2H); 7.40(mc, 1H);                                        7.55(mc, 2H);                                           2.002                                                                             2,6-Cl,Cl-phenyl                                                                        H CH.sub.3                                                                          OCH.sub.3                                                                          Cl                                                                               3.50(s, 3H), 4.05(s, 2H), 4.70(s, 2H),                                         7.40(mc, 1H), 7.55(mc, 2H)                              2.003                                                                             2-F-phenyl                                                                              H CH.sub.3                                                                          Cl  Cl                                                                               3.57(s, 3H); 4.49(s, 2H); 7.08-7.60(m-4H);              2.004                                                                             2-F-phenyl                                                                              H CH.sub.3                                                                          OCH.sub.3                                                                          Cl                                                                               3.48(s, 3H); 4.07(s, 3H); 4.44(s, 2H);                                         7.18(mc, 2H); 7.35(mc, 1H); 7.52(mc,                    __________________________________________________________________________                            1H);                                               

                  TABLE 3                                                          ______________________________________                                          ##STR20##                     Ic                                                                                 .sup.1 HNMR[d.sup.6 DMSO,                                                      δ(ppm)];                              No.  A       R.sup.1                                                                              R.sup.2                                                                            R.sup.3                                                                            R.sup.4                                                                            R.sup.5                                                                            mp[°C.]                              ______________________________________                                         3.001                                                                               phenyl  H     H   H   H   H   7.15(dd, 1H); 7.55(mc, 3H);                                                    7.65(dd, 1H);                                                                  7.90(mc, 2H); 8.05(dd,                      ______________________________________                                                                            1H);                                   

The herbicidal action of the sulfonamides of the formula I on the growth of plants is demonstrated by the following greenhouse experiments.

The vessels employed were plastic flowerpots having a volume of 300 cm³ and filled with a sandy loam containing about 3.0% humus. The seeds of the test plants were sown separately, according to species.

For the preemergence treatment, the formulated active ingredients were applied to the surface of the soil immediately after the seeds had been sown. The compounds were emulsified or suspended in water as vehicle, and sprayed through finely distributing nozzles.

After the agents had been applied, the vessels were lightly sprinkler-irrigated to induce germination and growth. Transparent plastic covers were then placed on the vessels until the plants had taken root. The cover ensured uniform germination of the plants, insofar as this was not impaired by the active ingredients.

For the postemergence treatment, plants were used which had been sown in the pots and grown there, or they were grown separately as seedlings and transplanted to the pots a few days before treatment. The plants were grown, depending on growth form, to a height of 3 to 15 cm before the compounds, suspended or emulsified in water, were sprayed on to them through finely distributing nozzles. The application rate for postemergence treatment was 0.5 kg/ha.

The pots wer set up in the greenhouse, heat-loving species at 20° to 35° C., and species from moderate climates at 10° to 20° C. The experiments were run for from 2 to 4 weeks. During this period the plants were tended and their reactions to the various treatments assessed. The assessment scale ws 0 to 100, 100 denoting nonemergence or complete destruction of at least the visible plant parts, and 0 denoting no damage or normal growth.

The plants employed for the experiments were Chenopodium album, Chrysanthemum corinarium, Matricaria inodora, Sinapis alba, and Zea mays.

Compounds 1.009 and 1.057, applied postemergence at a rate of 0.5 kg/ha, combated unwanted broadleaved plants very well and were tolerated by Indian corn. 

We claim:
 1. A sulfonamide of the formulae ##STR21## where R¹ is hydrogen or C₁ -C₄ -alkyl,R² isC₁ -C₆ -alkyl which can be substituted by one to five halogens and/or one of the following: C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy, C₁ -C₄ -alkylthio, C₁ -C₄ -haloalkylthio, phenyl, phenoxy or phenylthio; C₃ -C₄ -alkenyl, C₃ -C₄ -alkynyl; a saturated or singly unsaturated 5- to 7-membered heterocycle which contains one or two nitrogen, oxygen and/or sulfur atoms and which can have one to three of the following substituents: halogen, C₁ -C₄ -alkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkyl, C₁ -C₄ -haloalkoxy, C₁ -C₄ -alkylthio, C₁ -C₄ -haloalkylthio, and/or phenyl, phenoxy and/or phenylthio; R³ and R⁴ are halogen;C₁ -C₄ -alkoxy, C₁ -C₄ -alkylthio, C₂ -C₆ -alkenyl, C₂ -C₆ -alkenyloxy, C₂ -C₆ -alkenylthio, C₂ -C₆ -alkynyl, C₂ -C₆ -alkynyloxy and/or C₂ -C₆ -alkynylthio, it being possible for these radicals to be substituted by one to five halogens and/or by one of the following groups: C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy, C₂ -C₄ -alkylthio, C₁ -C₄ -haloalkylthio, phenyl, phenoxy or phenylthio; C₃ -C₆ -cycloalkyl, C₃ -C₆ -cycloalkylthio, C₅ -C₆ -cycloalkenyl, C₃ -C₆ -cycloalkoxy, C₅ -C₆ -cyclokenyloxy, C₅ -C₆ -cycloalkenylthio, phenyl, phenoxy, phenylthio, benzyl, benzyloxy or benzylthio, it being possible for these cyclic groups to be substituted by one to five halogens and/or one to three of the following: C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy, C₁ -C₄ -alkylthio, C₁ -C₄ -haloalkylthio, phenyl, phenoxy, phenylthio, benzyl, benzyloxy and/or benzylthio; the groups mentioned under R² or NR⁷ R⁸, where R⁷ and R⁸ are hydrogen, C₁ -C₆ -alkyl, C₃ -C₆ -alkenyl, C₃ -C₆ -alkynyl, C₃ -C₆ -cycloalkyl, C₅ -C₆ -cycloalkenyl, phenyl and/or benzyl, it being possible for the aromatic rings in turn to be substituted once to five times by halogen and/or once to three times by C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy and/or C₁ -C₄ -haloalkoxy, or together are a C₄ -C₆ -alkylene bridge which can be interrupted by an oxygen, sulfur or a nitrogen atom, it being possible for these bridges in turn to carry one to three C₁ -C₄ -alkyl groups; X is nitrogen or ═CR⁵ --, where R⁵ is one of the radicals R³, n is 0 or 1 and A is phenyl, naphthyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl, 1,3,5-triazinyl, 1,2,4-triazinyl, 1,2,3-triazinyl, tetrazinyl, pyrrolyl, furyl, thienyl, pyrazolyl, imidazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, 1,2,3-triazolyl, 1,2,4-triazolyl, tetrazolyl, thiadiazolyl, indolyl, isoindolyl, thionaphthyl, quinolyl, isoquinolyl, cinnolinyl, phthalazinyl, quinazolyl, quinoxalyl, indazolyl, naphthyridinyl, benzothiazolyl, benzimidazolyl, benzofuryl, benzoxazolyl and benzotriazolyl, and these aromatic rings substituted by one to five of the halogens, fluorine, chlorine and bromine, and/or one to three of the following: cyano, nitro, thiocyanato, --COR⁶ where R⁶ is hydroxyl, amino or one of the radicals R³, --SO_(m) R⁶ where m is 1 or 2, and/or the radicals mentioned for R³.
 2. A sulfonamide of the formulae ##STR22## where R¹ is hydrogen or C₁ -C₄ -alkyl,R² is hydrogen R³ and R⁴ are halogen;C₁ -C₄ -alkoxy, C₁ -C₄ -alkylthio, C₂ -C₆ -alkenyl, C₂ -C₆ -alkenyloxy, C₂ -C₆ -alkenylthio, C₂ -C₆ -alkynyl, C₂ -C₆ -alkynyloxy and/or C₂ -C₆ -alkynylthio, it being possible for these radicals to be substituted by one to five halogens and/or by one of the following groups: C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy, C₂ -C₄ -alkylthio, C₁ -C₄ -haloalkylthio, phenyl, phenoxy or phenylthio; C₃ -C₆ -cycloalkyl, C₃ -C₆ -cycloalkylthio, C₅ -C₆ -cycloalkenyl, C₃ -C₆ -cycloalkoxy, C₅ -C₆ -cyclokenyloxy, C₅ -C₆ -cycloalkenylthio, phenyl, phenoxy, phenylthio, benzyl, benzyloxy or benzylthio, it being possible for these cyclic groups to be substituted by one to five halogens and/or one to three of the following: C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy, C₁ -C₄ -alkylthio, C₁ -C₄ -haloalkylthio, phenyl, phenoxy, phenylthio, benzyl, benzyloxy and/or benzylthio; C₁ -C₆ -alkyl which can be substituted by one to five halogens and/or one of the following: C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkoxy, C₁ -C₄ -alkylthio, C₁ -C₄ -haloalkylthio, phenyl, phenoxy or phenylthio; C₃ -C₄ -alkenyl, C₃ -C₄ -alkynyl; a suturated or singly unsaturated 5- to 7-membered heterocycle which contains one or two nitrogen, oxygen and/or sulfur atoms and which can have one to three of the following substituents; halogen, C₁ -C₄ -alkyl, C₁ -C₄ -alkoxy, C₁ -C₄ -haloalkyl, C₁ -C₄ -haloalkoxy, C₁ -C₄ -alkylthio, C₁ -C₄ -haloalkylthio and/or phenyl, phenoxy and/or phenylthio; or NR⁷ R⁸, where R⁷ and R⁸ are hydrogen, C₁ -C₆ -alkyl, C₃ -C₆ -alkenyl, C₃ -C₆ -alkynyl, C₃ -C₆ -cycloalkyl, C₅ -C₆ -cycloalkenyl, phenyl and/or benzyl, it being possible for the aromatic rings in turn to be substituted once to five times by halogen and/or once to three times by C₁ -C₄ -alkyl, C₁ -C₄ -haloalkyl, C₁ -C₄ -alkoxy and/or C₁ -C₄ -haloalkoxy, or together are a C₄ -C₆ -alkylene bridge which can be interrupted by an oxygen, sulfur or a nitrogen atom, it being possible for these bridges in turn to carry one to three C₁ -C₄ -alkyl groups; X is nitrogen or ═CR⁵ --, where R⁵ is one of the radicals R³, n is 0 or 1 and A is phenyl, pyridyl, naphthyl, quinolyl, thienyl, pyrazolyl or N-methyl-pyrazolyl, and one of these aromatic radicals substituted by one to three of the following, in particular: nitro, cyano, fluorine, chlorine, bromine, ethyl, propyl, isopropyl, trifluoromethyl, methoxy, ethoxy, 1-methylethoxy, 1,1-dimethylethoxy, trifluoromethoxy, trifluoroethoxy, chloroethoxy, methoxymethyl, ethoxymethyl, methoxyethyl, ethoxyethyl, methoxyethoxy, ethoxyethoxy, methylthio, ethylthio, methyl- and ethylsulfonyl, methoxycarbonyl, ethoxycarbonyl, iso-propoxycarbonyl, methyl- and ethylcarbonyl, N,N-dimethylsulfamoyl and N,N-dimethylcarbamoyl, and agriculturally useful salts thereof.
 3. A sulfonamide of the formulae I or Ib as defined in claim 1, whereinA is phenyl, pyridyl, naphthyl, quinolyl, thienyl or pyrazolyl, and one of these aromatic radicals substituted by one to three of the following, in particular: nitro, cyano, fluorine, chlorine, ethyl, propyl, isopropyl, trifluoromethyl, methoxy, ethoxy, 1-methylethoxy, 1,1-dimethylethoxy, trifluoromethoxy, trifluoroethoxy, chloroethoxy, methoxymethyl, ethoxymethyl, methoxyethyl, ethoxyethyl, methoxyethoxy, ethoxyethoxy, methylthio, ethylthio, methyl- and ethylsulfonyl, methoxycarbonyl, ethoxycarbonyl, iso-propoxycarbonyl, methyl- and ethylcarbonyl, N,N-dimethylsulfamoyl and N,N-dimethylcarbamoyl, and agriculturally useful salts thereof.
 4. A herbicidal composition containing a sulfonamide of the formula Ia or Ib as set forth in claim 2, or in agriculturally useful salt thereof, and conventional formulation auxiliaries.
 5. A herbicidal composition containing a sulfonamide of the formula Ia or Ib as set forth in claim 1, or an agriculturally useful salt thereof, and conventional formulation auxiliaries.
 6. A process for combating the growth of unwanted plants, wherein a sulfonamide of the formula Ia or Ib as set forth in claim 1 is allowed to act on the plants and/or their habitat.
 7. A composition for influencing plant growth, containing a sulfonamide of the formula Ia or Ib as set forth in claim 1, or an agriculturally useful salt thereof, and conventional formulation auxiliaries.
 8. A process for influencing plant growth, wherein a sulfonamide of the formula Ia or Ib as set forth in claim 1 or a salt thereof, is allowed to act on the plants and/or their habitat. 